Zou, Weiping

Understanding the tumor immune microenvironment (TIME) for effective therapy

Binnewies, M., Roberts, E. W., Kersten, K., Chan, V., Fearon, D. F., Merad, M., Coussens, L. M., Gabrilovich, D. I., Ostrand-Rosenberg, S., Hedrick, C. C., et al. (2018) · Nature Medicine

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 6,145

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Curiel, T. J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M., Conejo-Garcia, J. R., Zhang, L., Burow, M., et al. (2004) · Nature Medicine

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 5,151

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Wang, W., Green, M., Choi, J. E., Gijón, M., Kennedy, P. D., Johnson, J. K., Liao, P., Lang, X., Kryczek, I., Sell, A., et al. (2019) · Nature

Ferroptosis and cancer prognosisCancer Immunotherapy and Biomarkers

Cited by 2,880

Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy

Yu, T., Guo, F., Yu, Y., Sun, T., Ma, D., Han, J., Qian, Y., Kryczek, I., Sun, D., Nagarsheth, N., et al. (2017) · Cell

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 2,198

Immunosuppressive networks in the tumour environment and their therapeutic relevance

Zou, W. (2005) · Nature Reviews Cancer

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 2,057

Inhibitory B7-family molecules in the tumour microenvironment

Zou, W., & Chen, L. (2008) · Nature Reviews Immunology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 1,608

Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity

Curiel, T. J., Wei, S., Dong, H., Alvarez, X., Cheng, P., Mottram, P., Krzysiek, R., Knutson, K. L., Daniel, B., Zimmermann, M. C., et al. (2003) · Nature Medicine

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 1,314

Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy

Peng, D., Kryczek, I., Nagarsheth, N., Zhao, L., Wei, S., Wang, W., Sun, Y., Zhao, E., Vatan, L., Szeliga, W., et al. (2015) · Nature

Cancer Immunotherapy and BiomarkersEpigenetics and DNA Methylation

Cited by 1,201

T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment

Crespo, J., Sun, H., Welling, T. H., Tian, Z., & Zou, W. (2013) · Current Opinion in Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 752

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

Kryczek, I., Zou, L., Rodriguez, P., Zhu, G., Wei, S., Mottram, P., Brumlik, M., Cheng, P., Curiel, T., Myers, L., et al. (2006) · The Journal of Experimental Medicine

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 748

Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor

Maj, T., Wang, W., Crespo, J., Zhang, H., Wang, W., Wei, S., Zhao, L., Vatan, L., Shao, I., Szeliga, W., et al. (2017) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 733

Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

Li, H., Wu, K., Tao, K., Chen, L., Zheng, Q., Lu, X., Liu, J., Shi, L., Liu, C., Wang, G., et al. (2012) · Hepatology

Galectins and Cancer BiologyCancer Immunotherapy and Biomarkers

Cited by 496

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction

Zhao, E., Maj, T., Kryczek, I., Li, W., Wu, K., Zhao, L., Wei, S., Crespo, J., Wan, S., Vatan, L., et al. (2016) · Nature Immunology

Cancer Immunotherapy and BiomarkersCancer, Hypoxia, and Metabolism

Cited by 405

Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions

Wu, K., Kryczek, I., Chen, L., Zou, W., & Welling, T. H. (2009) · Cancer Research

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 380

Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma

Chen, H.-M., Yu, Y.-N., Wang, J.-L., Lin, Y.-W., Kong, X., Yang, C.-Q., Yang, L., Liu, Z.-J., Yuan, Y.-Z., Liu, F., et al. (2013) · The American Journal of Clinical Nutrition

Gut microbiota and healthNutritional Studies and Diet

Cited by 321

Human T H 17 Cells Are Long-Lived Effector Memory Cells

Kryczek, I., Zhao, E., Liu, Y., Wang, Y., Vatan, L., Szeliga, W., Moyer, J., Klimczak, A., Lange, A., & Zou, W. (2011) · Science Translational Medicine

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 278

The Role of Tumor Microenvironment in Cancer Immunotherapy

Frankel, T., Lanfranca, M. P., & Zou, W. (2017) · Advances in Experimental Medicine and Biology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 173

Dual biological effects of the cytokines interleukin-10 and interferon-γ

Wilke, C. M., Wei, S., Wang, L., Kryczek, I., Kao, J., & Zou, W. (2011) · Cancer Immunology Immunotherapy

Cancer Immunotherapy and BiomarkersCytokine Signaling Pathways and Interactions

Cited by 138

Induction of antigen-specific regulatory T lymphocytes by human dendritic cells expressing the glucocorticoid-induced leucine zipper

Hamdi, H., Godot, V., Maillot, M.-C., Prejean, M. V., Cohen, N., Krzysiek, R., Lemoine, F. M., Zou, W., & Emilie, D. (2007) · Blood

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 126

Interleukin 22 signaling regulates acinar cell plasticity to promote pancreatic tumor development in mice

Perusina Lanfranca, M., Zhang, Y., Girgis, A., Kasselman, S., Lazarus, J., Kryczek, I., Delrosario, L., Rhim, A., Koneva, L., Sartor, M., et al. (2020) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchCytokine Signaling Pathways and Interactions

Cited by 81