Kiser, Philip D.

Chemistry of the Retinoid (Visual) Cycle

Kiser, P. D., Golczak, M., & Palczewski, K. (2014) · Chemical Reviews

Retinoids in leukemia and cellular processesPhotoreceptor and optogenetics research

Cited by 353

Key enzymes of the retinoid (visual) cycle in vertebrate retina

Kiser, P. D., Golczak, M., Maeda, A., & Palczewski, K. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 177

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

Kiser, P. D., Golczak, M., Lodowski, D. T., Chance, M. R., & Palczewski, K. (2009) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 158

Structural basis of carotenoid cleavage: From bacteria to mammals

Sui, X., Kiser, P. D., Lintig, J. V., & Palczewski, K. (2013) · Archives of Biochemistry and Biophysics

Metal-Catalyzed Oxygenation MechanismsEnzyme Structure and Function

Cited by 139

The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision

von Lintig, J., Kiser, P. D., Golczak, M., & Palczewski, K. (2010) · Trends in Biochemical Sciences

Retinoids in leukemia and cellular processesPhotoreceptor and optogenetics research

Cited by 119

Retinoids and Retinal Diseases

Kiser, P. D., & Palczewski, K. (2016) · Annual Review of Vision Science

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 108

Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina

Golczak, M., Maeda, A., Bereta, G., Maeda, T., Kiser, P. D., Hunzelmann, S., von Lintig, J., Blaner, W. S., & Palczewski, K. (2008) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 93

Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins

Golczak, M., Kiser, P. D., Sears, A. E., Lodowski, D. T., Blaner, W. S., & Palczewski, K. (2012) · Journal of Biological Chemistry

Enzyme Structure and FunctionLipid metabolism and biosynthesis

Cited by 77

Molecular pharmacodynamics of emixustat in protection against retinal degeneration

Zhang, J., Kiser, P. D., Badiee, M., Palczewska, G., Dong, Z., Golczak, M., Tochtrop, G. P., & Palczewski, K. (2015) · Journal of Clinical Investigation

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 75

The Biochemical Basis of Vitamin A Production from the Asymmetric Carotenoid β-Cryptoxanthin

Kelly, M. E., Ramkumar, S., Sun, W., Colon Ortiz, C., Kiser, P. D., Golczak, M., & von Lintig, J. (2018) · ACS Chemical Biology

Retinoids in leukemia and cellular processesAntioxidant Activity and Oxidative Stress

Cited by 74

Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis

Kiser, P. D., Farquhar, E. R., Shi, W., Sui, X., Chance, M. R., & Palczewski, K. (2012) · Proceedings of the National Academy of Sciences

Enzyme Structure and FunctionPhotoreceptor and optogenetics research

Cited by 63

Membrane-binding and enzymatic properties of RPE65

Kiser, P. D., & Palczewski, K. (2010) · Progress in Retinal and Eye Research

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 62

Lrat-specific domain facilitates Vitamin A metabolism by domain swapping in HRASLS3

Golczak, M., Sears, A. E., Kiser, P. D., & Palczewski, K. (2015) · Nature Chemical Biology

Enzyme Structure and FunctionRetinoids in leukemia and cellular processes

Cited by 58

Stereospecificity of Retinol Saturase: Absolute Configuration, Synthesis, and Biological Evaluation of Dihydroretinoids

Moise, A. R., Domínguez, M., Alvarez, S., Alvarez, R., Schupp, M., Cristancho, A. G., Kiser, P. D., de Lera, A. R., Lazar, M. A., & Palczewski, K. (2008) · Journal of the American Chemical Society

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 40

Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition

Sander, C. L., Sears, A. E., Pinto, A. F. M., Choi, E. H., Kahremany, S., Gao, F., Salom, D., Jin, H., Pardon, E., Suh, S., et al. (2021) · Journal of Cell Biology

Lipid Membrane Structure and BehaviorLipid metabolism and biosynthesis

Cited by 36

Impact of Retinal Disease-Associated RPE65 Mutations on Retinoid Isomerization

Bereta, G., Kiser, P. D., Golczak, M., Sun, W., Heon, E., Saperstein, D. A., & Palczewski, K. (2008) · Biochemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 36

Structural biology of 11- cis- retinaldehyde production in the classical visual cycle

Daruwalla, A., Choi, E. H., Palczewski, K., & Kiser, P. D. (2018) · Biochemical Journal

Photoreceptor and optogenetics researchRetinoids in leukemia and cellular processes

Cited by 28

Identification and Characterization of Novel Inhibitors of Mammalian Aspartyl Aminopeptidase

Chen, Y., Tang, H., Seibel, W., Papoian, R., Oh, K., Li, X., Zhang, J., Golczak, M., Palczewski, K., & Kiser, P. D. (2014) · Molecular Pharmacology

Renin-Angiotensin System StudiesPeptidase Inhibition and Analysis

Cited by 14