Bedja, Djahida

Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome

Habashi, J. P., Judge, D. P., Holm, T. M., Cohn, R. D., Loeys, B. L., Cooper, T. K., Myers, L., Klein, E. C., Liu, G., Calvi, C., et al. (2006) · Science

Connective tissue disorders researchAortic aneurysm repair treatments

Cited by 1,794

Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

Kageyama, Y., Hoshijima, M., Seo, K., Bedja, D., Sysa‐Shah, P., Andrabi, S. A., Chen, W., Höke, A., Dawson, V. L., Dawson, T. M., et al. (2014) · The EMBO Journal

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 420

Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

Lee, D. I., Zhu, G., Sasaki, T., Cho, G.-S., Hamdani, N., Holewinski, R., Jo, S.-H., Danner, T., Zhang, M., Rainer, P. P., et al. (2015) · Nature

Phosphodiesterase function and regulationCardiovascular Function and Risk Factors

Cited by 353

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

Sussan, T. E., Rangasamy, T., Blake, D. J., Malhotra, D., El-Haddad, H., Bedja, D., Yates, M. S., Kombairaju, P., Yamamoto, M., Liby, K. T., et al. (2009) · Proceedings of the National Academy of Sciences

Chronic Obstructive Pulmonary Disease (COPD) ResearchGenomics, phytochemicals, and oxidative stress

Cited by 346

Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy

Baldeviano, G. C., Barin, J. G., Talor, M. V., Srinivasan, S., Bedja, D., Zheng, D., Gabrielson, K., Iwakura, Y., Rose, N. R., & Cihakova, D. (2010) · Circulation Research

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 334

Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy

Chelko, S. P., Asimaki, A., Lowenthal, J., Bueno-Beti, C., Bedja, D., Scalco, A., Amat-Alarcon, N., Andersen, P., Judge, D. P., Tung, L., et al. (2019) · Circulation

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 192

Cardiac fibroblasts mediate IL-17A–driven inflammatory dilated cardiomyopathy

Wu, L., Ong, S., Talor, M. V., Barin, J. G., Baldeviano, G. C., Kass, D. A., Bedja, D., Zhang, H., Sheikh, A., Margolick, J. B., et al. (2014) · Journal of Experimental Medicine

Cardiac Fibrosis and RemodelingViral Infections and Immunology Research

Cited by 181

Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy

Chelko, S. P., Asimaki, A., Andersen, P., Bedja, D., Amat-Alarcon, N., DeMazumder, D., Jasti, R., MacRae, C. A., Leber, R., Kleber, A. G., et al. (2016) · JCI Insight

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 180

PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress

Ranek, M. J., Kokkonen-Simon, K. M., Chen, A., Dunkerly-Eyring, B. L., Vera, M. P., Oeing, C. U., Patel, C. H., Nakamura, T., Zhu, G., Bedja, D., et al. (2019) · Nature

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 130

Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n

Coronado, M. J., Brandt, J. E., Kim, E., Bucek, A., Bedja, D., Abston, E. D., Shin, J., Gabrielson, K. L., Mitzner, W., & Fairweather, D. (2012) · American Journal of Physiology-Heart and Circulatory Physiology

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 116

Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy

Diny, N. L., Baldeviano, G. C., Talor, M. V., Barin, J. G., Ong, S., Bedja, D., Hays, A. G., Gilotra, N. A., Coppens, I., Rose, N. R., et al. (2017) · Journal of Experimental Medicine

Viral Infections and Immunology ResearchEosinophilic Disorders and Syndromes

Cited by 99

Th2 Regulation of Viral Myocarditis in Mice: Different Roles for TLR3 versus TRIF in Progression to Chronic Disease

Abston, E. D., Coronado, M. J., Bucek, A., Bedja, D., Shin, J., Kim, J. B., Kim, E., Gabrielson, K. L., Georgakopoulos, D., Mitzner, W., et al. (2012) · Clinical and Developmental Immunology

Viral Infections and Immunology ResearchImmune Response and Inflammation

Cited by 94

Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy

Chelko, S. P., Keceli, G., Carpi, A., Doti, N., Agrimi, J., Asimaki, A., Beti, C. B., Miyamoto, M., Amat-Codina, N., Bedja, D., et al. (2021) · Science Translational Medicine

Cardiac electrophysiology and arrhythmiasCardiovascular Effects of Exercise

Cited by 92

Impaired up-regulation of CD25 on CD4 + T cells in IFN-γ knockout mice is associated with progression of myocarditis to heart failure

Afanasyeva, M., Georgakopoulos, D., Belardi, D. F., Bedja, D., Fairweather, D., Wang, Y., Kaya, Z., Gabrielson, K. L., Rodriguez, E. R., Caturegli, P., et al. (2005) · Proceedings of the National Academy of Sciences

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 89

IL-33 Independently Induces Eosinophilic Pericarditis and Cardiac Dilation: ST2 Improves Cardiac Function

Abston, E. D., Barin, J. G., Cihakova, D., Bucek, A., Coronado, M. J., Brandt, J. E., Bedja, D., Kim, J. B., Georgakopoulos, D., Gabrielson, K. L., et al. (2012) · Circulation: Heart Failure

IL-33, ST2, and ILC PathwaysViral Infections and Immunology Research

Cited by 69

Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy

Chung, H. S., Kim, G. E., Holewinski, R. J., Venkatraman, V., Zhu, G., Bedja, D., Kass, D. A., & Van Eyk, J. E. (2017) · Proceedings of the National Academy of Sciences

Muscle Physiology and DisordersRedox biology and oxidative stress

Cited by 33

Hypereosinophilia causes progressive cardiac pathologies in mice

Diny, N. L., Wood, M. K., Won, T., Talor, M. V., Lukban, C., Bedja, D., Wang, N., Kalinoski, H., Daoud, A., Talbot, C. C., et al. (2023) · iScience

Eosinophilic Disorders and SyndromesCardiac Fibrosis and Remodeling

Cited by 7