Somervaille, Tim C.P.

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia

Somervaille, T. C. P., & Cleary, M. L. (2006) · Cancer Cell

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 582

The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells

Harris, W. J., Huang, X., Lynch, J. T., Spencer, G. J., Hitchin, J. R., Li, Y., Ciceri, F., Blaser, J. G., Greystoke, B. F., Jordan, A. M., et al. (2012) · Cancer Cell

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 566

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy

Wang, Z., Smith, K. S., Murphy, M., Piloto, O., Somervaille, T. C. P., & Cleary, M. L. (2008) · Nature

Acute Lymphoblastic Leukemia researchWnt/β-catenin signaling in development and cancer

Cited by 265

Hematopoietic Stem Cell Quiescence Is Maintained by Compound Contributions of the Retinoblastoma Gene Family

Viatour, P., Somervaille, T. C., Venkatasubrahmanyam, S., Kogan, S., McLaughlin, M. E., Weissman, I. L., Butte, A. J., Passegué, E., & Sage, J. (2008) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 178

MicroRNA programs in normal and aberrant stem and progenitor cells

Arnold, C. P., Tan, R., Zhou, B., Yue, S.-B., Schaffert, S., Biggs, J. R., Doyonnas, R., Lo, M.-C., Perry, J. M., Renault, V. M., et al. (2011) · Genome Research

MicroRNA in disease regulationHematopoietic Stem Cell Transplantation

Cited by 65

Safety, Phamacokinetics (PK), Pharmacodynamics (PD) and Preliminary Activity in Acute Leukemia of Ory-1001, a First-in-Class Inhibitor of Lysine-Specific Histone Demethylase 1A (LSD1/KDM1A): Initial Results from a First-in-Human Phase 1 Study

Somervaille, T., Salamero, O., Montesinos, P., Willekens, C., Perez Simon, J. A., Pigneux, A., Recher, C., Popat, R., Molinero, C., Mascaro, C., et al. (2016) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 46

Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML

Nicosia, L., Boffo, F. L., Ceccacci, E., Conforti, F., Pallavicini, I., Bedin, F., Ravasio, R., Massignani, E., Somervaille, T. C. P., Minucci, S., et al. (2022) · Oncogene

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 31

PU.1 and Junb: suppressing the formation of acute myeloid leukemia stem cells.

Somervaille, T. C. P., & Cleary, M. L. (2006) · Cancer Cell

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 25