Grammas, Paula

Strategies to advance translational research into brain barriers

Neuwelt, E., Abbott, N. J., Abrey, L., Banks, W. A., Blakley, B., Davis, T., Engelhardt, B., Grammas, P., Nedergaard, M., Nutt, J., et al. (2008) · The Lancet Neurology

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 474

Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease

Grammas, P. (2011) · Journal of Neuroinflammation

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 432

Nitric Oxide Synthase Activity Is Elevated in Brain Microvessels in Alzheimer′s Disease

Dorheim, M. A., Tracey, W. R., Pollock, J. S., & Grammas, P. (1994) · Biochemical and Biophysical Research Communications

Nitric Oxide and Endothelin EffectsAlzheimer's disease research and treatments

Cited by 216

Thrombin, a mediator of neurotoxicity and memory impairment

Mhatre, M., Nguyen, A., Kashani, S., Pham, T., Adesina, A., & Grammas, P. (2004) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

Cited by 105

Brain Endothelial Cells Synthesize Neurotoxic Thrombin in Alzheimer’s Disease

Yin, X., Wright, J., Wall, T., & Grammas, P. (2010) · The American Journal of Pathology

Alzheimer's disease research and treatmentsBarrier Structure and Function Studies

Cited by 104

Blood-Cerebrospinal Fluid Barrier Gradients in Mild Cognitive Impairment and Alzheimer's Disease: Relationship to Inflammatory Cytokines and Chemokines

Ott, B. R., Jones, R. N., Daiello, L. A., de la Monte, S. M., Stopa, E. G., Johanson, C. E., Denby, C., & Grammas, P. (2018) · Frontiers in Aging Neuroscience

Barrier Structure and Function StudiesCerebrospinal fluid and hydrocephalus

Cited by 91

Expression of Macrophage Inflammatory Protein 1-α is Elevated in Alzheimer's Vessels and is Regulated by Oxidative Stress

Tripathy, D., Thirumangalakudi, L., & Grammas, P. (2007) · Journal of Alzheimer's Disease

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 51

Endothelin-1 is Elevated in Alzheimer's Disease Brain Microvessels and is Neuroprotective

Luo, J., & Grammas, P. (2010) · Journal of Alzheimer's Disease

Nitric Oxide and Endothelin EffectsAlzheimer's disease research and treatments

Cited by 39