Sharma, Kumar

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

Kang, H. M., Ahn, S. H., Choi, P., Ko, Y.-A., Han, S. H., Chinga, F., Park, A. S. D., Tao, J., Sharma, K., Pullman, J., et al. (2015) · Nature Medicine

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 1,555

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

Pearson, K. J., Baur, J. A., Lewis, K. N., Peshkin, L., Price, N. L., Labinskyy, N., Swindell, W. R., Kamara, D., Minor, R. K., Perez, E., et al. (2008) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 1,162

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

Garrett-Bakelman, F. E., Darshi, M., Green, S. J., Gur, R. C., Lin, L., Macias, B. R., McKenna, M. J., Meydan, C., Mishra, T., Nasrini, J., et al. (2019) · Science

Spaceflight effects on biologySpace exploration and regulation

Cited by 1,128

Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease

Sharma, K., Karl, B., Mathew, A. V., Gangoiti, J. A., Wassel, C. L., Saito, R., Pu, M., Sharma, S., You, Y.-H., Wang, L., et al. (2013) · Journal of the American Society of Nephrology

Chronic Kidney Disease and DiabetesMetabolomics and Mass Spectrometry Studies

Cited by 571

Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus

Vallon, V., Rose, M., Gerasimova, M., Satriano, J., Platt, K. A., Koepsell, H., Cunard, R., Sharma, K., Thomson, S. C., & Rieg, T. (2013) · American Journal of Physiology-Renal Physiology

Diabetes Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 370

Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications

Sas, K. M., Kayampilly, P., Byun, J., Nair, V., Hinder, L. M., Hur, J., Zhang, H., Lin, C., Qi, N. R., Michailidis, G., et al. (2016) · JCI Insight

Chronic Kidney Disease and DiabetesMetabolomics and Mass Spectrometry Studies

Cited by 268

Multiple Metabolic Hits Converge on CD36 as Novel Mediator of Tubular Epithelial Apoptosis in Diabetic Nephropathy

Susztak, K., Ciccone, E., McCue, P., Sharma, K., & Böttinger, E. P. (2005) · PLoS Medicine

Chronic Kidney Disease and DiabetesAdvanced Glycation End Products research

Cited by 214

A role for tubular Na+/H+exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin

Onishi, A., Fu, Y., Patel, R., Darshi, M., Crespo-Masip, M., Huang, W., Song, P., Freeman, B., Kim, Y. C., Soleimani, M., et al. (2020) · American Journal of Physiology-Renal Physiology

Ion Transport and Channel RegulationDiabetes Treatment and Management

Cited by 206

Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney

Sato, Y., Mii, A., Hamazaki, Y., Fujita, H., Nakata, H., Masuda, K., Nishiyama, S., Shibuya, S., Haga, H., Ogawa, O., et al. (2016) · JCI Insight

Acute Kidney Injury ResearchChronic Kidney Disease and Diabetes

Cited by 148

Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice

Ghosh, S., Khazaei, M., Moien-Afshari, F., Ang, L. S., Granville, D. J., Verchere, C. B., Dunn, S. R., McCue, P., Mizisin, A., Sharma, K., et al. (2009) · American Journal of Physiology-Renal Physiology

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 113

Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes

Satriano, J., Mansoury, H., Deng, A., Sharma, K., Vallon, V., Blantz, R. C., & Thomson, S. C. (2010) · American Journal of Physiology-Cell Physiology

Chronic Kidney Disease and DiabetesTelomeres, Telomerase, and Senescence

Cited by 93

The Role of Aldosteronism in Causing Obesity-Related Cardiovascular Risk

Calhoun, D. A., & Sharma, K. (2010) · Cardiology Clinics

Hormonal Regulation and HypertensionCardiovascular Disease and Adiposity

Cited by 74

Effect of renal tubule-specific knockdown of the Na+/H+exchanger NHE3 in Akita diabetic mice

Onishi, A., Fu, Y., Darshi, M., Crespo-Masip, M., Huang, W., Song, P., Patel, R., Kim, Y. C., Nespoux, J., Freeman, B., et al. (2019) · American Journal of Physiology-Renal Physiology

Ion Transport and Channel RegulationChronic Kidney Disease and Diabetes

Cited by 71

Effects of dapagliflozin on urinary metabolites in people with type 2 diabetes

Mulder, S., Heerspink, H. J. L., Darshi, M., Kim, J. J., Laverman, G. D., Sharma, K., & Pena, M. J. (2019) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementChronic Kidney Disease and Diabetes

Cited by 65