Watkins, Simon C.

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Kagan, V. E., Mao, G., Qu, F., Angeli, J. P. F., Doll, S., Croix, C. S., Dar, H. H., Liu, B., Tyurin, V. A., Ritov, V. B., et al. (2017) · Nature Chemical Biology

Ferroptosis and cancer prognosisAntioxidant Activity and Oxidative Stress

Cited by 3,029

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.

Montecalvo, A., Larregina, A. T., Shufesky, W. J., Beer Stolz, D., Sullivan, M. L. G., Karlsson, J. M., Baty, C. J., Gibson, G. A., Erdos, G., Wang, Z., et al. (2012) · Blood

Extracellular vesicles in diseaseMicroRNA in disease regulation

Cited by 1,429

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

Chu, C. T., Ji, J., Dagda, R. K., Jiang, J. F., Tyurina, Y. Y., Kapralov, A. A., Tyurin, V. A., Yanamala, N., Shrivastava, I. H., Mohammadyani, D., et al. (2013) · Nature Cell Biology

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 1,083

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

Phinney, D. G., Di Giuseppe, M., Njah, J., Sala, E., Shiva, S., St Croix, C. M., Stolz, D. B., Watkins, S. C., Di, Y. P., Leikauf, G. D., et al. (2015) · Nature Communications

Extracellular vesicles in diseaseMesenchymal stem cell research

Cited by 1,007

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

Scharping, N. E., Menk, A. V., Moreci, R. S., Whetstone, R. D., Dadey, R. E., Watkins, S. C., Ferris, R. L., & Delgoffe, G. M. (2016) · Immunity

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 848

Persistent Activation of ERK Contributes to Glutamate-induced Oxidative Toxicity in a Neuronal Cell Line and Primary Cortical Neuron Cultures

Stanciu, M., Wang, Y., Kentor, R., Burke, N., Watkins, S., Kress, G., Reynolds, I., Klann, E., Angiolieri, M. R., Johnson, J. W., et al. (2000) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingRedox biology and oxidative stress

Cited by 539

Intramuscular lipid content is increased in obesity and decreased by weight loss

Goodpaster, B. H., Theriault, R., Watkins, S. C., & Kelley, D. E. (2000) · Metabolism

Diabetes, Cardiovascular Risks, and LipoproteinsAdipose Tissue and Metabolism

Cited by 526

Skeletal Muscle Lipid Content and Oxidative Enzyme Activity in Relation to Muscle Fiber Type in Type 2 Diabetes and Obesity

He, J., Watkins, S., & Kelley, D. E. (2001) · Diabetes

Muscle Physiology and DisordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 518

NF-κB inhibition delays DNA damage–induced senescence and aging in mice

Tilstra, J. S., Robinson, A. R., Wang, J., Gregg, S. Q., Clauson, C. L., Reay, D. P., Nasto, L. A., St Croix, C. M., Usas, A., Vo, N., et al. (2012) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsNF-κB Signaling Pathways

Cited by 462

CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity

Mo, F.-E., Muntean, A. G., Chen, C.-C., Stolz, D. B., Watkins, S. C., & Lau, L. F. (2002) · Molecular and Cellular Biology

Connective Tissue Growth Factor ResearchPregnancy and preeclampsia studies

Cited by 416

Impaired wound healing and angiogenesis in eNOS-deficient mice

Lee, P. C., Salyapongse, A. N., Bragdon, G. A., Shears, L. L., Watkins, S. C., Edington, H. D. J., & Billiar, T. R. (1999) · American Journal of Physiology-Heart and Circulatory Physiology

Wound Healing and TreatmentsNitric Oxide and Endothelin Effects

Cited by 369

Donor dendritic cell–derived exosomes promote allograft-targeting immune response

Liu, Q., Rojas-Canales, D. M., Divito, S. J., Shufesky, W. J., Stolz, D. B., Erdos, G., Sullivan, M. L. G., Gibson, G. A., Watkins, S. C., Larregina, A. T., et al. (2016) · Journal of Clinical Investigation

Transplantation: Methods and OutcomesExtracellular vesicles in disease

Cited by 302

Disabled‐2 exhibits the properties of a cargo‐selective endocytic clathrin adaptor

Mishra, S. K., Keyel, P. A., Hawryluk, M. J., Agostinelli, N. R., Watkins, S. C., & Traub, L. M. (2002) · The EMBO Journal

Cellular transport and secretionCaveolin-1 and cellular processes

Cited by 302

Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis

Fouquerel, E., Barnes, R. P., Uttam, S., Watkins, S. C., Bruchez, M. P., & Opresko, P. L. (2019) · Molecular Cell

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 275

Oral-resident natural Th17 cells and γδ T cells control opportunistic Candida albicans infections

Conti, H. R., Peterson, A. C., Brane, L., Huppler, A. R., Hernández-Santos, N., Whibley, N., Garg, A. V., Simpson-Abelson, M. R., Gibson, G. A., Mamo, A. J., et al. (2014) · Journal of Experimental Medicine

T-cell and B-cell ImmunologyAntifungal resistance and susceptibility

Cited by 254

Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium

Dar, H. H., Tyurina, Y. Y., Mikulska-Ruminska, K., Shrivastava, I., Ting, H.-C., Tyurin, V. A., Krieger, J., St. Croix, C. M., Watkins, S., Bayir, E., et al. (2018) · Journal of Clinical Investigation

Ferroptosis and cancer prognosisBacterial biofilms and quorum sensing

Cited by 251

The effect of non-insulin-dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle.

Kelley, D. E., Mintun, M. A., Watkins, S. C., Simoneau, J. A., Jadali, F., Fredrickson, A., Beattie, J., & Thériault, R. (1996) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 228

Starving Neurons Show Sex Difference in Autophagy

Du, L., Hickey, R. W., Bayir, H., Watkins, S. C., Tyurin, V. A., Guo, F., Kochanek, P. M., Jenkins, L. W., Ren, J., Gibson, G., et al. (2009) · Journal of Biological Chemistry

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 204

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging

Robinson, A. R., Yousefzadeh, M. J., Rozgaja, T. A., Wang, J., Li, X., Tilstra, J. S., Feldman, C. H., Gregg, S. Q., Johnson, C. H., Skoda, E. M., et al. (2018) · Redox Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 155

Conjugated linoleic acid is a preferential substrate for fatty acid nitration

Bonacci, G., Baker, P. R. S., Salvatore, S. R., Shores, D., Khoo, N. K. H., Koenitzer, J. R., Vitturi, D. A., Woodcock, S. R., Golin-Bisello, F., Cole, M. P., et al. (2012) · Journal of Biological Chemistry

Fatty Acid Research and HealthAntioxidant Activity and Oxidative Stress

Cited by 147

Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/Bid Pathway

Wang, X., Ryter, S. W., Dai, C., Tang, Z.-L., Watkins, S. C., Yin, X.-M., Song, R., & Choi, A. M. K. (2003) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 136

A Single Common Portal for Clathrin-mediated Endocytosis of Distinct Cargo Governed by Cargo-selective Adaptors

Keyel, P. A., Mishra, S. K., Roth, R., Heuser, J. E., Watkins, S. C., & Traub, L. M. (2006) · Molecular Biology of the Cell

Cellular transport and secretionCholesterol and Lipid Metabolism

Cited by 134

Changes Induced by Physical Activity and Weight Loss in the Morphology of Intermyofibrillar Mitochondria in Obese Men and Women

Toledo, F. G. S., Watkins, S., & Kelley, D. E. (2006) · The Journal of Clinical Endocrinology & Metabolism

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 126

Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding

Ma, L., Umasankar, P. K., Wrobel, A. G., Lymar, A., McCoy, A. J., Holkar, S. S., Jha, A., Pradhan-Sundd, T., Watkins, S. C., Owen, D. J., et al. (2016) · Developmental Cell

Cellular transport and secretionBiotin and Related Studies

Cited by 115