Linton, MacRae F.

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice

Cyrus, T., Witztum, J. L., Rader, D. J., Tangirala, R., Fazio, S., Linton, M. F., & Funk, C. D. (1999) · Journal of Clinical Investigation

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 523

Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation

Linton, M. F., Atkinson, J. B., & Fazio, S. (1995) · Science

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 478

Residual Cardiovascular Risk Despite Optimal LDL Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges

Sampson, U. K., Fazio, S., & Linton, M. F. (2012) · Current Atherosclerosis Reports

Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 439

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.

Linton, M. F., Gish, R., Hubl, S. T., Bütler, E., Esquivel, C., Bry, W. I., Boyles, J. K., Wardell, M. R., & Young, S. G. (1991) · Journal of Clinical Investigation

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 367

Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages

Fazio, S., Babaev, V. R., Murray, A. B., Hasty, A. H., Carter, K. J., Gleaves, L. A., Atkinson, J. B., & Linton, M. F. (1997) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 295

Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation

Yancey, P. G., Blakemore, J., Ding, L., Fan, D., Overton, C. D., Zhang, Y., Linton, M. F., & Fazio, S. (2010) · Arteriosclerosis, Thrombosis, and Vascular Biology

Phagocytosis and Immune RegulationAtherosclerosis and Cardiovascular Diseases

Cited by 168

Deletion of Macrophage LDL Receptor–Related Protein Increases Atherogenesis in the Mouse

Overton, C. D., Yancey, P. G., Major, A. S., Linton, M. F., & Fazio, S. (2007) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 159

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis

Tao, H., Yancey, P. G., Babaev, V. R., Blakemore, J. L., Zhang, Y., Ding, L., Fazio, S., & Linton, M. F. (2015) · Journal of Lipid Research

Phagocytosis and Immune RegulationAtherosclerosis and Cardiovascular Diseases

Cited by 143

The role of fibrates in managing hyperlipidemia: Mechanisms of action and clinical efficacy

Fazio, S., & Linton, M. F. (2004) · Current Atherosclerosis Reports

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 118

Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation

Hasty, A. H., Linton, M. F., Brandt, S. J., Babaev, V. R., Gleaves, L. A., & Fazio, S. (1999) · Circulation

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 105

Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor

Linton, M. F., Hasty, A. H., Babaev, V. R., & Fazio, S. (1998) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 100

Low-Density Lipoprotein Receptor–Related Protein 1 Prevents Early Atherosclerosis by Limiting Lesional Apoptosis and Inflammatory Ly-6C high Monocytosis: Evidence That the Effects Are Not Apolipoprotein E Dependent

Yancey, P. G., Ding, Y., Fan, D., Blakemore, J. L., Zhang, Y., Ding, L., Zhang, J., Linton, M. F., & Fazio, S. (2011) · Circulation

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 83

Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice

Yamamoto, S., Zuo, Y., Ma, J., Yancey, P. G., Hunley, T. E., Motojima, M., Fogo, A. B., Linton, M. F., Fazio, S., Ichikawa, I., et al. (2011) · Nephrology Dialysis Transplantation

Atherosclerosis and Cardiovascular DiseasesDialysis and Renal Disease Management

Cited by 74

Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding

Zhu, L., Shi, J., Luu, T. N., Neuman, J. C., Trefts, E., Yu, S., Palmisano, B. T., Wasserman, D. H., Linton, M. F., & Stafford, J. M. (2018) · Molecular Metabolism

Cholesterol and Lipid MetabolismEstrogen and related hormone effects

Cited by 66

Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice

Fazio, S., Babaev, V. R., Burleigh, M. E., Major, A. S., Hasty, A. H., & Linton, M. F. (2002) · Journal of Lipid Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 58

Macrophages, lipoprotein metabolism, and atherosclerosis: insights from murine bone marrow transplantation studies

Linton, M. F., & Fazio, S. (1999) · Current Opinion in Lipidology

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 51

Loss of Macrophage Low-Density Lipoprotein Receptor–Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-α Inhibition

Zhu, L., Giunzioni, I., Tavori, H., Covarrubias, R., Ding, L., Zhang, Y., Ormseth, M., Major, A. S., Stafford, J. M., Linton, M. F., et al. (2016) · Arteriosclerosis, Thrombosis, and Vascular Biology

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 46

Impaired secretion of apolipoprotein E2 from macrophages

Fan, D., Qiu, S., Overton, C. D., Yancey, P. G., Swift, L. L., Jerome, W. G., Linton, M. F., & Fazio, S. (2007) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismAlzheimer's disease research and treatments

Cited by 27

Isoform-specific effects of apolipoprotein E on atherogenesis: gene transduction studies in mice

Yoshida, H., Hasty, A. H., Major, A. S., Ishiguro, H., Su, Y. R., Gleaves, L. A., Babaev, V. R., Linton, M. F., & Fazio, S. (2001) · Circulation

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 24

Macrophage-derived apoESendai suppresses atherosclerosis while causing lipoprotein glomerulopathy in hyperlipidemic mice

Tavori, H., Fan, D., Giunzioni, I., Zhu, L., Linton, M. F., Fogo, A. B., & Fazio, S. (2014) · Journal of Lipid Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 10