Orlando, David A.

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Whyte, W. A., Orlando, D. A., Hnisz, D., Abraham, B. J., Lin, C. Y., Kagey, M. H., Rahl, P. B., Lee, T. I., & Young, R. A. (2013) · Cell

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 4,143

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

Lovén, J., Hoke, H. A., Lin, C. Y., Lau, A., Orlando, D. A., Vakoc, C. R., Bradner, J. E., Lee, T. I., & Young, R. A. (2013) · Cell

Protein Degradation and InhibitorsChromatin Remodeling and Cancer

Cited by 2,961

Mediator and cohesin connect gene expression and chromatin architecture

Kagey, M. H., Newman, J. J., Bilodeau, S., Zhan, Y., Orlando, D. A., van Berkum, N. L., Ebmeier, C. C., Goossens, J., Rahl, P. B., Levine, S. S., et al. (2010) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,939

Revisiting Global Gene Expression Analysis

Lovén, J., Orlando, D. A., Sigova, A. A., Lin, C. Y., Rahl, P. B., Burge, C. B., Levens, D. L., Lee, T. I., & Young, R. A. (2012) · Cell

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 616

Enhancer decommissioning by LSD1 during embryonic stem cell differentiation

Whyte, W. A., Bilodeau, S., Orlando, D. A., Hoke, H. A., Frampton, G. M., Foster, C. T., Cowley, S. M., & Young, R. A. (2012) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 602

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

Ceol, C. J., Houvras, Y., Jane-Valbuena, J., Bilodeau, S., Orlando, D. A., Battisti, V., Fritsch, L., Lin, W. M., Hollmann, T. J., Ferré, F., et al. (2011) · Nature

Melanoma and MAPK PathwaysZebrafish Biomedical Research Applications

Cited by 542

Quantitative ChIP-Seq normalization reveals global modulation of the epigenome

Orlando, D. A., Chen, M. W., Brown, V. E., Solanki, S., Choi, Y. J., Olson, E. R., Fritz, C. C., Bradner, J. E., & Guenther, M. G. (2014) · Cell Reports

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 503