Prendergast, George C.

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy

Muller, A. J., DuHadaway, J. B., Donover, P. S., Sutanto-Ward, E., & Prendergast, G. C. (2005) · Nature Medicine

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 1,064

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

Prendergast, G. C., Lawe, D., & Ziff, E. B. (1991) · Cell

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

Cited by 558

Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

Takahashi, N., Duprez, L., Grootjans, S., Cauwels, A., Nerinckx, W., DuHadaway, J. B., Goossens, V, Roelandt, R., Van Hauwermeiren, F., Libert, C., et al. (2012) · Cell Death & Disease

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 465

BIN1 is a novel MYC–interacting protein with features of a tumour suppressor

Sakamuro, D., Elliott, K. J., Wechsler-Reya, R., & Prendergast, G. C. (1996) · Nature Genetics

Cancer-related Molecular PathwaysMechanisms of cancer metastasis

Cited by 387

Modulation of Statin-Activated Shedding of Alzheimer APP Ectodomain by ROCK

Pedrini, S., Carter, T. L., Prendergast, G., Petanceska, S., Ehrlich, M. E., & Gandy, S. (2005) · PLoS Medicine

Alzheimer's disease research and treatmentsProtein Kinase Regulation and GTPase Signaling

Cited by 154

Structural Analysis of the Human BIN1 Gene

Wechsler-Reya, R., Sakamuro, D., Zhang, J., Duhadaway, J., & Prendergast, G. C. (1997) · Journal of Biological Chemistry

RNA Research and SplicingGenomics and Chromatin Dynamics

Cited by 142

Targeted Disruption of the Murine Bin1/Amphiphysin II Gene Does Not Disable Endocytosis but Results in Embryonic Cardiomyopathy with Aberrant Myofibril Formation

Muller, A. J., Baker, J. F., DuHadaway, J. B., Ge, K., Farmer, G., Donover, P. S., Meade, R., Reid, C., Grzanna, R., Roach, A. H., et al. (2003) · Molecular and Cellular Biology

Congenital heart defects researchCardiomyopathy and Myosin Studies

Cited by 139

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program

Elliott, K., Ge, K., Du, W., & Prendergast, G. C. (2000) · Oncogene

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 106

BIN1 regulates BACE1 intracellular trafficking and amyloid-β production

Miyagawa, T., Ebinuma, I., Morohashi, Y., Hori, Y., Young Chang, M., Hattori, H., Maehara, T., Yokoshima, S., Fukuyama, T., Tsuji, S., et al. (2016) · Human Molecular Genetics

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 95

The Crystal Structure of the BAR Domain from Human Bin1/Amphiphysin II and Its Implications for Molecular Recognition

Casal, E., Federici, L., Zhang, W., Fernandez-Recio, J., Priego, E.-M., Miguel, R. N., DuHadaway, J. B., Prendergast, G. C., Luisi, B. F., & Laue, E. D. (2006) · Biochemistry

Cellular transport and secretionProtein Structure and Dynamics

Cited by 77

BAR the door: Cancer suppression by amphiphysin-like genes

Prendergast, G. C., Muller, A. J., Ramalingam, A., & Chang, M. Y. (2009) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Cancer-related Molecular PathwaysCellular transport and secretion

Cited by 68

Immunohistochemical analysis of Bin1/Amphiphysin II in human tissues: Diverse sites of nuclear expression and losses in prostate cancer

DuHadaway, J. B., Lynch, F. J., Brisbay, S., Bueso‐Ramos, C., Troncoso, P., McDonnell, T., & Prendergast, G. C. (2003) · Journal of Cellular Biochemistry

Prostate Cancer Treatment and ResearchCancer-related Molecular Pathways

Cited by 49

The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria

Schultz, C. W., McCarthy, G. A., Nerwal, T., Nevler, A., DuHadaway, J. B., McCoy, M. D., Jiang, W., Brown, S. Z., Goetz, A., Jain, A., et al. (2021) · Molecular Cancer Therapeutics

Pancreatic and Hepatic Oncology ResearchCancer, Hypoxia, and Metabolism

Cited by 34

Bin1 Interacts with and Restrains the DNA End-Binding Protein Complex Ku

Ramalingam, A., Farmer, G. E., Stamato, T., & Prendergast, G. C. (2007) · Cell Cycle

DNA Repair MechanismsTelomeres, Telomerase, and Senescence

Cited by 18