Kunz, Wolfram S.

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., et al. (2018) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,924

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

The International League Against Epilepsy Consortium on Complex Epilepsies, Abou-Khalil, B., Auce, P., Avbersek, A., Bahlo, M., Balding, D. J., Bast, T., Baum, L., Becker, A. J., Becker, F., et al. (2018) · Nature Communications

Epilepsy research and treatmentGenetic Associations and Epidemiology

Cited by 482

Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis

Wiedemann, F. R., Winkler, K., Kuznetsov, A. V., Bartels, C., Vielhaber, S., Feistner, H., & Kunz, W. S. (1998) · Journal of the Neurological Sciences

Amyotrophic Lateral Sclerosis ResearchMitochondrial Function and Pathology

Cited by 262

Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

Kornblum, C., Nicholls, T. J., Haack, T. B., Schöler, S., Peeva, V., Danhauser, K., Hallmann, K., Zsurka, G., Rorbach, J., Iuso, A., et al. (2013) · Nature Genetics

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 232

Microglial CD33-related Siglec-E inhibits neurotoxicity by preventing the phagocytosis-associated oxidative burst

Claude, J., Linnartz-Gerlach, B., Kudin, A. P., Kunz, W. S., & Neumann, H. (2013) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsGlycosylation and Glycoproteins Research

Cited by 98

N-acetyl Cysteine Treatment Rescues Cognitive Deficits Induced by Mitochondrial Dysfunction in G72/G30 Transgenic Mice

Otte, D.-M., Sommersberg, B., Kudin, A., Guerrero, C., Albayram, Ö., Filiou, M. D., Frisch, P., Yilmaz, Ö., Drews, E., Turck, C. W., et al. (2011) · Neuropsychopharmacology

Mitochondrial Function and PathologyParkinson's Disease Mechanisms and Treatments

Cited by 97

Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging

Baris, O. R., Ederer, S., Neuhaus, J. F. G., von Kleist-Retzow, J.-C., Wunderlich, C. M., Pal, M., Wunderlich, F. T., Peeva, V., Zsurka, G., Kunz, W. S., et al. (2015) · Cell Metabolism

Mitochondrial Function and PathologyCardiac electrophysiology and arrhythmias

Cited by 87

Sites of generation of reactive oxygen species in homogenates of brain tissue determined with the use of respiratory substrates and inhibitors

Kudin, A. P., Malinska, D., & Kunz, W. S. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 84

Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease

Nicholls, T. J., Zsurka, G., Peeva, V., Schöler, S., Szczesny, R. J., Cysewski, D., Reyes, A., Kornblum, C., Sciacco, M., Moggio, M., et al. (2014) · Human Molecular Genetics

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 78

Re-evaluation of the dysfunction of mitochondrial respiratory chain in skeletal muscle of patients with Parkinson?s disease

Winkler-Stuck, K., Kirches, E., Mawrin, C., Dietzmann, K., Lins, H., Wallesch, C.-W., Kunz, W. S., & Wiedemann, F. R. (2005) · Journal of Neural Transmission

Mitochondrial Function and PathologyParkinson's Disease Mechanisms and Treatments

Cited by 63

Extending the phenotypic spectrum of RBFOX 1 deletions: Sporadic focal epilepsy

Lal, D., Pernhorst, K., Klein, K. M., Reif, P., Tozzi, R., Toliat, M. R., Winterer, G., Neubauer, B., Nürnberg, P., Rosenow, F., et al. (2015) · Epilepsia

Epilepsy research and treatmentGenetics and Neurodevelopmental Disorders

Cited by 40

Complete failure of insulin-transmitted signaling, but not obesity-induced insulin resistance, impairs respiratory chain function in muscle

Franko, A., von Kleist-Retzow, J. C., Böse, M., Sanchez-Lasheras, C., Brodesser, S., Krut, O., Kunz, W. S., Wiedermann, D., Hoehn, M., Stöhr, O., et al. (2012) · Journal of Molecular Medicine

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 39