Lamb, David C.

Functional profiling of the Saccharomyces cerevisiae genome

Giaever, G., Chu, A. M., Ni, L., Connelly, C., Riles, L., Véronneau, S., Dow, S., Lucau-Danila, A., Anderson, K., André, B., et al. (2002) · Nature

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 4,316

Resistance to fluconazole and cross‐resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ5,6‐desaturation

Kelly, S. L., Lamb, D. C., Kelly, D. E., Manning, N. J., Loeffler, J., Hebart, H., Schumacher, U., & Einsele, H. (1997) · FEBS Letters

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 351

Multiple Molecular Mechanisms Contribute to a Stepwise Development of Fluconazole Resistance in Clinical Candida albicans Strains

Franz, R., Kelly, S. L., Lamb, D. C., Kelly, D. E., Ruhnke, M., & Morschhäuser, J. (1998) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 339

Mode of Action and Resistance to Azole Antifungals Associated with the Formation of 14α-Methylergosta-8,24(28)-dien-3β,6α-diol

Kelly, S. L., Lamb, D. C., Corran, A. J., Baldwin, B. C., & Kelly, D. E. (1995) · Biochemical and Biophysical Research Communications

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 296

Resistance to amphotericin B associated with defective sterol Δ8→7isomerase in a Cryptococcus neoformans strain from an AIDS patient

Kelly, S. L., Lamb, D. C., Taylor, M., Corran, A. J., Baldwin, B. C., & Powderly, W. G. (1994) · FEMS Microbiology Letters

Fungal Infections and StudiesAntifungal resistance and susceptibility

Cited by 133

The G464S amino acid substitution in Candida albicans sterol 14α-demethylase causes fluconazole resistance in the clinic through reduced affinity

Kelly, S. L., Lamb, D. C., Loeffler, J., Einsele, H., & Kelly, D. E. (1999) · Biochemical and Biophysical Research Communications

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 116

Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51)

Warrilow, A. G. S., Martel, C. M., Parker, J. E., Melo, N., Lamb, D. C., Nes, W. D., Kelly, D. E., & Kelly, S. L. (2010) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityPharmacogenetics and Drug Metabolism

Cited by 112

A second FMN binding site in yeast NADPH-cytochrome P450 reductase suggests a mechanism of electron transfer by diflavin reductases

Lamb, D. C., Kim, Y., Yermalitskaya, L. V., Yermalitsky, V. N., Lepesheva, G. I., Kelly, S. L., Waterman, M. R., & Podust, L. M. (2006) · Structure

Enzyme Structure and FunctionMetal-Catalyzed Oxygenation Mechanisms

Cited by 60

Structural Analysis of Cytochrome P450 105N1 Involved in the Biosynthesis of the Zincophore, Coelibactin

Zhao, B., Moody, S. C., Hider, R. C., Lei, L., Kelly, S. L., Waterman, M. R., & Lamb, D. C. (2012) · International Journal of Molecular Sciences

Microbial Natural Products and BiosynthesisMetal-Catalyzed Oxygenation Mechanisms

Cited by 42