Sauna, Zuben E.

A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity

Kimchi-Sarfaty, C., Oh, J. M., Kim, I.-W., Sauna, Z. E., Calcagno, A. M., Ambudkar, S. V., & Gottesman, M. M. (2007) · Science

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 2,416

Understanding the contribution of synonymous mutations to human disease

Sauna, Z. E., & Kimchi-Sarfaty, C. (2011) · Nature Reviews Genetics

Genomics and Rare DiseasesRNA Research and Splicing

Cited by 1,022

Recent advances in (therapeutic protein) drug development

Lagassé, H. A. D., Alexaki, A., Simhadri, V. L., Katagiri, N. H., Jankowski, W., Sauna, Z. E., & Kimchi-Sarfaty, C. (2017) · F1000Research

Monoclonal and Polyclonal Antibodies ResearchBiosimilars and Bioanalytical Methods

Cited by 481

Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population

Simhadri, V. L., McGill, J., McMahon, S., Wang, J., Jiang, H., & Sauna, Z. E. (2018) · Molecular Therapy - Methods & Clinical Development

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 241

Immunogenicity assessment during the development of protein therapeutics

Rosenberg, A. S., & Sauna, Z. E. (2018) · Journal of Pharmacy and Pharmacology

Biosimilars and Bioanalytical Methodsvaccines and immunoinformatics approaches

Cited by 131

Evaluating and mitigating the immunogenicity of therapeutic proteins

Sauna, Z. E., Lagassé, D., Pedras-Vasconcelos, J., Golding, B., & Rosenberg, A. S. (2018) · Trends in biotechnology

Biosimilars and Bioanalytical MethodsMonoclonal and Polyclonal Antibodies Research

Cited by 118

Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

Alexaki, A., Hettiarachchi, G. K., Athey, J. C., Katneni, U. K., Simhadri, V., Hamasaki-Katagiri, N., Nanavaty, P., Lin, B., Takeda, K., Freedberg, D., et al. (2019) · Scientific Reports

RNA and protein synthesis mechanismsHemophilia Treatment and Research

Cited by 78