Merkle, Florian T.
Wellcome/MRC Cambridge Stem Cell Institute · University of Cambridge · Wellcome/MRC Institute of Metabolic Science · Wellcome Trust · Medical Research Council
8 papers on CoChatORCID 0000-0002-8513-2998
Most cited papers
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Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain
Mirzadeh, Z., Merkle, F. T., Soriano-Navarro, M., Garcia-Verdugo, J. M., & Alvarez-Buylla, A. (2008) · Cell stem cell
Neurogenesis and neuroplasticity mechanismsCerebrospinal fluid and hydrocephalus
Cited by 1,015
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Adult Ependymal Cells Are Postmitotic and Are Derived from Radial Glial Cells during Embryogenesis
Spassky, N., Merkle, F. T., Flames, N., Tramontin, A. D., García-Verdugo, J. M., & Alvarez-Buylla, A. (2005) · The Journal of Neuroscience
Neurogenesis and neuroplasticity mechanismsCerebrospinal fluid and hydrocephalus
Cited by 717
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Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells
Maroof, A. M., Keros, S., Tyson, J. A., Ying, S.-W., Ganat, Y. M., Merkle, F. T., Liu, B., Goulburn, A., Stanley, E. G., Elefanty, A. G., et al. (2013) · Cell Stem Cell
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 596
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Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
Merkle, F. T., Ghosh, S., Kamitaki, N., Mitchell, J., Avior, Y., Mello, C., Kashin, S., Mekhoubad, S., Ilic, D., Charlton, M., et al. (2017) · Nature
Pluripotent Stem Cells ResearchCancer Genomics and Diagnostics
Cited by 506
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Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1
Kiskinis, E., Sandoe, J., Williams, L. A., Boulting, G. L., Moccia, R., Wainger, B. J., Han, S., Peng, T., Thams, S., Mikkilineni, S., et al. (2014) · Cell stem cell
Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders
Cited by 441
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A reference human induced pluripotent stem cell line for large-scale collaborative studies
Pantazis, C. B., Yang, A., Lara, E., McDonough, J. A., Blauwendraat, C., Peng, L., Oguro, H., Kanaujiya, J., Zou, J., Sebesta, D., et al. (2022) · Cell Stem Cell
Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering
Cited by 310
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Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease
Burberry, A., Suzuki, N., Wang, J.-Y., Moccia, R., Mordes, D. A., Stewart, M. H., Suzuki-Uematsu, S., Ghosh, S., Singh, A., Merkle, F. T., et al. (2016) · Science Translational Medicine
Amyotrophic Lateral Sclerosis ResearchT-cell and B-cell Immunology
Cited by 269
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Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus
Merkle, F. T., Neuhausser, W. M., Santos, D., Valen, E., Gagnon, J. A., Maas, K., Sandoe, J., Schier, A. F., & Eggan, K. (2015) · Cell Reports
CRISPR and Genetic EngineeringPluripotent Stem Cells Research
Cited by 152
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