Kang, Rui

Ferroptosis: process and function

Xie, Y., Hou, W., Song, X., Yu, Y., Huang, J., Sun, X., Kang, R., & Tang, D. (2016) · Cell Death & Differentiation

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 3,727

Autophagy promotes ferroptosis by degradation of ferritin

Hou, W., Xie, Y., Song, X., Sun, X., Lotze, M. T., Zeh, H. J., Kang, R., & Tang, D. (2016) · Autophagy

Ferroptosis and cancer prognosisAutophagy in Disease and Therapy

Cited by 2,332

Ferroptosis: machinery and regulation

Chen, X., Li, J., Kang, R., Klionsky, D. J., & Tang, D. (2021) · Autophagy

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 2,099

Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Sun, X., Ou, Z., Chen, R., Niu, X., Chen, D., Kang, R., & Tang, D. (2016) · Hepatology

Ferroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stress

Cited by 2,012

HMGB1 in health and disease

Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.-G., Yan, Z., et al. (2014) · Molecular Aspects of Medicine

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 956

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

Xie, Y., Zhu, S., Song, X., Sun, X., Fan, Y., Liu, J., Zhong, M., Yuan, H., Zhang, L., Billiar, T. R., et al. (2017) · Cell Reports

Ferroptosis and cancer prognosisCancer-related Molecular Pathways

Cited by 952

HSPB1 as a novel regulator of ferroptotic cancer cell death

Sun, X., Ou, Z., Xie, M., Kang, R., Fan, Y., Niu, X., Wang, H., Cao, L., & Tang, D. (2015) · Oncogene

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 666

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

Dai, E., Han, L., Liu, J., Xie, Y., Kroemer, G., Klionsky, D. J., Zeh, H. J., Kang, R., Wang, J., & Tang, D. (2020) · Autophagy

Immune cells in cancerFerroptosis and cancer prognosis

Cited by 613

HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

Zhu, S., Zhang, Q., Sun, X., Zeh, H. J., Lotze, M. T., Kang, R., & Tang, D. (2017) · Cancer Research

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 576

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

Tang, D., Kang, R., Cheh, C.-W., Livesey, K. M., Liang, X., Schapiro, N. E., Benschop, R., Sparvero, L. J., Amoscato, A. A., Tracey, K. J., et al. (2010) · Oncogene

Advanced Glycation End Products researchCell death mechanisms and regulation

Cited by 461

Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1

Tang, D., Shi, Y., Kang, R., Li, T., Xiao, W., Wang, H., & Xiao, X. (2007) · Journal of Leukocyte Biology

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 312

The BET family in immunity and disease

Wang, N., Wu, R., Tang, D., & Kang, R. (2021) · Signal Transduction and Targeted Therapy

Protein Degradation and InhibitorsGenomics and Chromatin Dynamics

Cited by 295

NUPR1 is a critical repressor of ferroptosis

Liu, J., Song, X., Kuang, F., Zhang, Q., Xie, Y., Kang, R., Kroemer, G., & Tang, D. (2021) · Nature Communications

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 290

MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells

Kuang, F., Liu, J., Xie, Y., Tang, D., & Kang, R. (2021) · Cell Chemical Biology

Ferroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stress

Cited by 199

Dual-AAV delivering split prime editor system for in vivo genome editing

Zhi, S., Chen, Y., Wu, G., Wen, J., Wu, J., Liu, Q., Li, Y., Kang, R., Hu, S., Wang, J., et al. (2022) · Molecular Therapy

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 174

The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

Kang, R., Loux, T., Tang, D., Schapiro, N. E., Vernon, P., Livesey, K. M., Krasinskas, A., Lotze, M. T., & Zeh, H. J. (2012) · Proceedings of the National Academy of Sciences

Advanced Glycation End Products researchPancreatic and Hepatic Oncology Research

Cited by 163

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’

Huang, J., Xie, Y., Sun, X., Zeh, H. J., Kang, R., Lotze, M. T., & Tang, D. (2015) · Ageing Research Reviews

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 144

Oncogenic KRAS blockade therapy: renewed enthusiasm and persistent challenges

Tang, D., Kroemer, G., & Kang, R. (2021) · Molecular Cancer

Protein Kinase Regulation and GTPase SignalingLung Cancer Treatments and Mutations

Cited by 80

SRC kinase drives multidrug resistance induced by KRAS-G12C inhibition

Song, X., Zhou, Z., Elmezayen, A., Wu, R., Yu, C., Gao, B., Minna, J. D., Westover, K. D., Zeh, H. J., Kroemer, G., et al. (2024) · Science Advances

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

Cited by 26

SRC at the Crossroads of KRAS Inhibitor Resistance: Mechanisms and Therapeutic Opportunities

Tian, H., Zhao, D., Zhou, Z., Kim, A., Huang, H., Lee, Y. J., Qu, Z., Kang, R., Zeh, H. J., Westover, K. D., et al. (2026) · Cancer Letters

Protein Kinase Regulation and GTPase SignalingLung Cancer Treatments and Mutations

Cited by 7