Zhang, Siyuan

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

Zhang, L., Zhang, S., Yao, J., Lowery, F. J., Zhang, Q., Huang, W.-C., Li, P., Li, M., Wang, X., Zhang, C., et al. (2015) · Nature

Extracellular vesicles in diseaseMicroRNA in disease regulation

Cited by 1,175

Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways

Zhang, S., Huang, W.-C., Li, P., Guo, H., Poh, S.-B., Brady, S. W., Xiong, Y., Tseng, L.-M., Li, S.-H., Ding, Z., et al. (2011) · Nature Medicine

HER2/EGFR in Cancer ResearchLung Cancer Treatments and Mutations

Cited by 515

PTEN, PIK3CA, p-AKT, and p-p70S6K Status

Esteva, F. J., Guo, H., Zhang, S., Santa-Maria, C., Stone, S., Lanchbury, J. S., Sahin, A. A., Hortobagyi, G. N., & Yu, D. (2010) · The American Journal of Pathology

HER2/EGFR in Cancer ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 285

Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy

Morrow, P. K., Wulf, G. M., Ensor, J., Booser, D. J., Moore, J. A., Flores, P. R., Xiong, Y., Zhang, S., Krop, I. E., Winer, E. P., et al. (2011) · Journal of Clinical Oncology

HER2/EGFR in Cancer ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 209

Stromal cell-laden 3D hydrogel microwell arrays as tumor microenvironment model for studying stiffness dependent stromal cell-cancer interactions

Yue, X., Nguyen, T. D., Zellmer, V., Zhang, S., & Zorlutuna, P. (2018) · Biomaterials

Cellular Mechanics and Interactions3D Printing in Biomedical Research

Cited by 97

3D hydrogel-based microwell arrays as a tumor microenvironment model to study breast cancer growth

Casey, J., Yue, X., Nguyen, T. D., Acun, A., Zellmer, V. R., Zhang, S., & Zorlutuna, P. (2017) · Biomedical Materials

Cellular Mechanics and Interactions3D Printing in Biomedical Research

Cited by 74

The Role of Multicellular Aggregation in the Survival of ErbB2-positive Breast Cancer Cells during Extracellular Matrix Detachment

Rayavarapu, R. R., Heiden, B., Pagani, N., Shaw, M. M., Shuff, S., Zhang, S., & Schafer, Z. T. (2015) · Journal of Biological Chemistry

HER2/EGFR in Cancer ResearchCell Adhesion Molecules Research

Cited by 42