Zhang, Feng
Broad Institute · McGovern Institute for Brain Research · Massachusetts Institute of Technology
65 papers on CoChatORCID 0000-0003-0178-7995
Most cited papers
- Verified
The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases
Altae-Tran, H., Kannan, S., Demircioglu, F. E., Oshiro, R., Nety, S. P., McKay, L. J., Dlakić, M., Inskeep, W. P., Makarova, K. S., Macrae, R. K., et al. (2021) · Science
CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology
Cited by 407
- Verified
A cellular and spatial map of the choroid plexus across brain ventricles and ages
Dani, N., Herbst, R. H., McCabe, C., Green, G. S., Kaiser, K., Head, J. P., Cui, J., Shipley, F. B., Jang, A., Dionne, D., et al. (2021) · Cell
Single-cell and spatial transcriptomicsCerebrospinal fluid and hydrocephalus
Cited by 388
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BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks
Yan, W. X., Mirzazadeh, R., Garnerone, S., Scott, D., Schneider, M. W., Kallas, T., Custodio, J., Wernersson, E., Li, Y., Gao, L., et al. (2017) · Nature Communications
CRISPR and Genetic EngineeringDNA Repair Mechanisms
Cited by 369
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Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects
Zhou, Y., Kaiser, T., Monteiro, P., Zhang, X., Van der Goes, M. S., Wang, D., Barak, B., Zeng, M., Li, C., Lu, C., et al. (2016) · Neuron
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 325
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Optical Pooled Screens in Human Cells
Feldman, D., Singh, A., Schmid-Burgk, J. L., Carlson, R. J., Mezger, A., Garrity, A. J., Zhang, F., & Blainey, P. C. (2019) · Cell
CRISPR and Genetic EngineeringNF-κB Signaling Pathways
Cited by 321
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In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes
Jin, X., Simmons, S. K., Guo, A., Shetty, A. S., Ko, M., Nguyen, L., Jokhi, V., Robinson, E., Oyler, P., Curry, N., et al. (2020) · Science
Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders
Cited by 317
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Point-of-care testing for COVID-19 using SHERLOCK diagnostics
Joung, J., Ladha, A., Saito, M., Segel, M., Bruneau, R., Huang, M.-L. W., Kim, N.-G., Yu, X., Li, J., Walker, B. D., et al. (2020) · medRxiv
SARS-CoV-2 detection and testingBiosensors and Analytical Detection
Cited by 317
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Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits
Platt, R. J., Zhou, Y., Slaymaker, I. M., Shetty, A. S., Weisbach, N. R., Kim, J.-A., Sharma, J., Desai, M., Sood, S., Kempton, H. R., et al. (2017) · Cell Reports
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 240
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Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors
Heller, E. A., Cates, H. M., Peña, C. J., Sun, H., Shao, N., Feng, J., Golden, S. A., Herman, J. P., Walsh, J. J., Mazei-Robison, M., et al. (2014) · Nature Neuroscience
Neurotransmitter Receptor Influence on BehaviorEpigenetics and DNA Methylation
Cited by 227
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Highly Parallel Profiling of Cas9 Variant Specificity
Schmid-Burgk, J. L., Gao, L., Li, D., Gardner, Z., Strecker, J., Lash, B., & Zhang, F. (2020) · Molecular Cell
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 197
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Compact RNA editors with small Cas13 proteins
Kannan, S., Altae-Tran, H., Jin, X., Madigan, V. J., Oshiro, R., Makarova, K. S., Koonin, E. V., & Zhang, F. (2022) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 176
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Multi-cellular communities are perturbed in the aging human brain and Alzheimer’s disease
Cain, A., Taga, M., McCabe, C., Green, G., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2020) · Nature Neuroscience
Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments
Cited by 143
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Genome Editing Abrogates Angiogenesis in Vivo
Huang, X., Zhou, G., Wu, W., Duan, Y., Ma, G., Song, J., Xiao, R., Vandenberghe, L., Zhang, F., D’Amore, P. A., et al. (2017) · Nature Communications
CRISPR and Genetic EngineeringAngiogenesis and VEGF in Cancer
Cited by 142
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Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease
Cain, A., Taga, M., McCabe, C., Green, G. S., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2023) · Nature Neuroscience
Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments
Cited by 142
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Structural basis for the altered PAM recognition by engineered CRISPR-Cpf1
Nishimasu, H., Yamano, T., Gao, L., Zhang, F., Ishitani, R., & Nureki, O. (2017) · Molecular Cell
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 102
- Verified
The transposon-encoded protein TnpB processes its own mRNA into ωRNA for guided nuclease activity
Nety, S. P., Altae-Tran, H., Kannan, S., Demircioglu, F. E., Faure, G., Hirano, S., Mears, K., Zhang, Y., Macrae, R. K., & Zhang, F. (2023) · The CRISPR Journal
CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology
Cited by 35
- Verified
Multiplex gene editing by CRISPR-Cpf1 through autonomous processing of a single crRNA array
Zetsche, B., Heidenreich, M., Mohanraju, P., Fedorova, I., Kneppers, J., DeGennaro, E. M., Winblad, N., Choudhury, S. R., Abudayyeh, O. O., Gootenberg, J. S., et al. (2016) · bioRxiv (Cold Spring Harbor Laboratory)
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 9
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