Chen, Jianjun

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huang, H., Weng, H., Sun, W., Qin, X., Shi, H., Wu, H., Zhao, B. S., Mesquita, A., Liu, C., Yuan, C. L., et al. (2018) · Nature Cell Biology

RNA modifications and cancerRNA Research and Splicing

Cited by 2,997

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Su, R., Dong, L., Li, C., Nachtergaele, S., Wunderlich, M., Qing, Y., Deng, X., Wang, Y., Weng, X., Hu, C., et al. (2018) · Cell

RNA modifications and cancerAcute Myeloid Leukemia Research

Cited by 1,137

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Huang, H., Weng, H., Zhou, K., Wu, T., Zhao, B. S., Sun, M., Chen, Z., Deng, X., Xiao, G., Auer, F., et al. (2019) · Nature

RNA modifications and cancerEpigenetics and DNA Methylation

Cited by 677

miR-21 plays a pivotal role in gastric cancer pathogenesis and progression

Zhang, Z., Li, Z., Gao, C., Chen, P., Chen, J., Liu, W., Xiao, S., & Lu, H. (2008) · Laboratory Investigation

MicroRNA in disease regulationHelicobacter pylori-related gastroenterology studies

Cited by 477

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

Weng, H., Huang, F., Yu, Z., Chen, Z., Prince, E., Kang, Y., Zhou, K., Li, W., Hu, J., Fu, C., et al. (2022) · Cancer Cell

RNA modifications and cancerAcute Myeloid Leukemia Research

Cited by 336

Crosstalk between epitranscriptomic and epigenetic mechanisms in gene regulation

Kan, R. L., Chen, J., & Sallam, T. (2022) · Trends in Genetics

RNA modifications and cancerEpigenetics and DNA Methylation

Cited by 308

YBX1 is required for maintaining myeloid leukemia cell survival by regulating BCL2 stability in an m6A-dependent manner

Feng, M., Xie, X., Han, G., Zhang, T., Li, Y., Li, Y., Yin, R., Wang, Q., Zhang, T., Wang, P., et al. (2021) · Blood

RNA modifications and cancerAcute Myeloid Leukemia Research

Cited by 213

RNA m6A regulates transcription via DNA demethylation and chromatin accessibility

Deng, S., Zhang, J., Su, J., Zuo, Z., Zeng, L., Liu, K., Zheng, Y., Huang, X., Bai, R., Zhuang, L., et al. (2022) · Nature Genetics

RNA modifications and cancerEpigenetics and DNA Methylation

Cited by 187

Identification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteins

Shi, Y., Chen, J., Weng, C., Chen, R., Zheng, Y., Chen, Q., & Tang, H. (2003) · Biochemical and Biophysical Research Communications

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 158

Mutations in FYCO1 Cause Autosomal-Recessive Congenital Cataracts

Chen, J., Ma, Z., Jiao, X., Fariss, R., Kantorow, W. L., Kantorow, M., Pras, E., Frydman, M., Pras, E., Riazuddin, S., et al. (2011) · The American Journal of Human Genetics

Connexins and lens biologyOcular Disorders and Treatments

Cited by 153

High-resolution characterization of gene function using single-cell CRISPR tiling screen

Yang, L., Chan, A. K. N., Miyashita, K., Delaney, C. D., Wang, X., Li, H., Pokharel, S. P., Li, S., Li, M., Xu, X., et al. (2021) · Nature Communications

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 45

AIM2 Inhibits BRAF-Mutant Colorectal Cancer Growth in a Caspase-1-Dependent Manner

Shah, S., Qin, S., Luo, Y., Huang, Y., Jing, R., Shah, J. N., Chen, J., Chen, H., & Zhong, M. (2021) · Frontiers in Cell and Developmental Biology

Cell death mechanisms and regulationColorectal Cancer Treatments and Studies

Cited by 19