Li, Hu

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA

Warren, L., Manos, P. D., Ahfeldt, T., Loh, Y.-H., Li, H., Lau, F., Ebina, W., Mandal, P. K., Smith, Z. D., Meissner, A., et al. (2010) · Cell Stem Cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 2,662

Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

Kim, H. J., Li, H., Collins, J. J., & Ingber, D. E. (2016) · Proceedings of the National Academy of Sciences

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 922

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Kasendra, M., Tovaglieri, A., Sontheimer-Phelps, A., Jalili-Firoozinezhad, S., Bein, A., Chalkiadaki, A., Scholl, W., Zhang, C., Rickner, H., Richmond, C. A., et al. (2018) · Scientific Reports

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 754

Deconstructing transcriptional heterogeneity in pluripotent stem cells

Kumar, R. M., Cahan, P., Shalek, A. K., Satija, R., Jay DaleyKeyser, A., Li, H., Zhang, J., Pardee, K., Gennert, D., Trombetta, J. J., et al. (2014) · Nature

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 356

p21 produces a bioactive secretome that places stressed cells under immunosurveillance

Sturmlechner, I., Zhang, C., Sine, C. C., van Deursen, E.-J., Jeganathan, K. B., Hamada, N., Grasic, J., Friedman, D., Stutchman, J. T., Can, I., et al. (2021) · Science

Cancer-related Molecular PathwaysImmune cells in cancer

Cited by 295

Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo

Apicco, D. J., Ash, P. E. A., Maziuk, B., LeBlang, C., Medalla, M., Al Abdullatif, A., Ferragud, A., Botelho, E., Ballance, H. I., Dhawan, U., et al. (2018) · Nature Neuroscience

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 281

Senescent alveolar macrophages promote early-stage lung tumorigenesis

Prieto, L. I., Sturmlechner, I., Graves, S. I., Zhang, C., Goplen, N. P., Yi, E. S., Sun, J., Li, H., & Baker, D. J. (2023) · Cancer Cell

Immune cells in cancerTelomeres, Telomerase, and Senescence

Cited by 212

Senescent cells: a therapeutic target for cardiovascular disease

Childs, B. G., Li, H., & van Deursen, J. M. (2018) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 192

Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy

Jiang, L., Lin, W., Zhang, C., Ash, P. E. A., Verma, M., Kwan, J., van Vliet, E., Yang, Z., Cruz, A. L., Boudeau, S., et al. (2021) · Molecular Cell

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 177

RNA binding proteins co-localize with small tau inclusions in tauopathy

Maziuk, B. F., Apicco, D. J., Cruz, A. L., Jiang, L., Ash, P. E. A., da Rocha, E. L., Zhang, C., Yu, W. H., Leszyk, J., Abisambra, J. F., et al. (2018) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 151

Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis

Childs, B. G., Zhang, C., Shuja, F., Sturmlechner, I., Trewartha, S., Velasco, R. F., Baker, D. J., Li, H., & van Deursen, J. M. (2021) · Nature Aging

Atherosclerosis and Cardiovascular DiseasesTelomeres, Telomerase, and Senescence

Cited by 76

Strategies for Genetically Engineering Hypoimmunogenic Universal Pluripotent Stem Cells

Zhao, W., Lei, A., Tian, L., Wang, X., Correia, C., Weiskittel, T., Li, H., Trounson, A., Fu, Q., Yao, K., et al. (2020) · iScience

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 53

Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Xing, Q. R., El Farran, C. A., Gautam, P., Chuah, Y. S., Warrier, T., Toh, C. X. D., Kang, N. Y., Sugii, S., Chang, Y. T., Xu, J., et al. (2020) · Science Advances

Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics

Cited by 51

Glycogen synthase kinase 3 activity enhances liver inflammation in MASH

Khoury, M., Guo, Q., Furuta, K., Correia, C., Meroueh, C., Kim Lee, H. S., Warasnhe, K., Valenzuela-Pérez, L., Mazar, A. P., Kim, I., et al. (2024) · JHEP Reports

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

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