Chen, Jun

Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury

Wang, G., Zhang, J., Hu, X., Zhang, L., Mao, L., Jiang, X., Liou, A. K.-F., Leak, R. K., Gao, Y., & Chen, J. (2013) · Journal of Cerebral Blood Flow & Metabolism

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 473

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

Shi, Y., Zhang, L., Pu, H., Mao, L., Hu, X., Jiang, X., Xu, N., Stetler, R. A., Zhang, F., Liu, X., et al. (2016) · Nature Communications

Barrier Structure and Function StudiesAcute Ischemic Stroke Management

Cited by 431

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis

Wang, G., Shi, Y., Jiang, X., Leak, R. K., Hu, X., Wu, Y., Pu, H., Li, W.-W., Tang, B., Wang, Y., et al. (2015) · Proceedings of the National Academy of Sciences

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 376

STAT6/Arg1 promotes microglia/macrophage efferocytosis and inflammation resolution in stroke mice

Cai, W., Dai, X., Chen, J., Zhao, J., Xu, M., Zhang, L., Yang, B., Zhang, W., Rocha, M., Nakao, T., et al. (2019) · JCI Insight

Neuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation

Cited by 317

Protective effects and mechanisms of sirtuins in the nervous system

Zhang, F., Wang, S., Gan, L., Vosler, P. S., Gao, Y., Zigmond, M. J., & Chen, J. (2011) · Progress in Neurobiology

Sirtuins and Resveratrol in MedicineNuclear Receptors and Signaling

Cited by 211

IL-4/STAT6 signaling facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice

Xu, J., Chen, Z., Yu, F., Liu, H., Ma, C., Xie, D., Hu, X., Leak, R. K., Chou, S. H. Y., Stetler, R. A., et al. (2020) · Proceedings of the National Academy of Sciences

Intracerebral and Subarachnoid Hemorrhage ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 180

Leptin Protects against 6-Hydroxydopamine-induced Dopaminergic Cell Death via Mitogen-activated Protein Kinase Signaling

Weng, Z., Signore, A. P., Gao, Y., Wang, S., Zhang, F., Hastings, T., Yin, X.-M., & Chen, J. (2007) · Journal of Biological Chemistry

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 163

Integrating spatial and single-cell transcriptomics to characterize the molecular and cellular architecture of the ischemic mouse brain

Han, B., Zhou, S., Zhang, Y., Chen, S., Xi, W., Liu, C., Zhou, X., Yuan, M., Yu, X., Li, L., et al. (2024) · Science Translational Medicine

Single-cell and spatial transcriptomicsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 143

Genome-wide transcriptomic analysis of microglia reveals impaired responses in aged mice after cerebral ischemia

Shi, L., Rocha, M., Zhang, W., Jiang, M., Li, S., Ye, Q., Hassan, S. H., Liu, L., Adair, M. N., Xu, J., et al. (2020) · Journal of Cerebral Blood Flow & Metabolism

Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments

Cited by 71

Microglia-specific deletion of histone deacetylase 3 promotes inflammation resolution, white matter integrity, and functional recovery in a mouse model of traumatic brain injury

Zhao, Y., Mu, H., Huang, Y., Li, S., Wang, Y., Stetler, R. A., Bennett, M. V. L., Dixon, C. E., Chen, J., & Shi, Y. (2022) · Journal of Neuroinflammation

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 47