Yang, Hsin-Sheng

The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation

Yang, H.-S., Jansen, A. P., Komar, A. A., Zheng, X., Merrick, W. C., Costes, S., Lockett, S. J., Sonenberg, N., & Colburn, N. H. (2003) · Molecular and Cellular Biology

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 494

Tumorigenesis Suppressor Pdcd4 Down-Regulates Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 Expression to Suppress Colon Carcinoma Cell Invasion

Yang, H.-S., Matthews, C. P., Clair, T., Wang, Q., Baker, A. R., Li, C.-C. H., Tan, T.-H., & Colburn, N. H. (2006) · Molecular and Cellular Biology

Mechanisms of cancer metastasisProtein Kinase Regulation and GTPase Signaling

Cited by 202

A Novel Function of the MA-3 Domains in Transformation and Translation Suppressor Pdcd4 Is Essential for Its Binding to Eukaryotic Translation Initiation Factor 4A

Yang, H.-S., Cho, M.-H., Zakowicz, H., Hegamyer, G., Sonenberg, N., & Colburn, N. H. (2004) · Molecular and Cellular Biology

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 199

A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation

Yang, H.-S., Jansen, A. P., Nair, R., Shibahara, K., Verma, A. K., Cmarik, J. L., & Colburn, N. H. (2001) · Oncogene

Mechanisms of cancer metastasisCancer-related Molecular Pathways

Cited by 185

Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors

Leupold, J. H., Yang, H.-S., Colburn, N. H., Asangani, I., Post, S., & Allgayer, H. (2007) · Oncogene

Protease and Inhibitor MechanismsMechanisms of cancer metastasis

Cited by 163

Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation

Yang, H.-S., Knies, J. L., Stark, C., & Colburn, N. H. (2003) · Oncogene

Cancer-related Molecular PathwaysMechanisms of cancer metastasis

Cited by 160

The role of Pdcd4 in tumour suppression and protein translation

Wang, Q., & Yang, H. (2018) · Biology of the Cell

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 113

Downregulation of E-cadherin is an essential event in activating β-catenin/Tcf-dependent transcription and expression of its target genes in Pdcd4 knockdown cells

Wang, Q., Sun, Z. X., Allgayer, H., & Yang, H. S. (2010) · Oncogene

Wnt/β-catenin signaling in development and cancerMechanisms of cancer metastasis

Cited by 89

Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma

Wang, Q., Zhu, J., Wang, Y.-W., Dai, Y., Wang, Y.-L., Wang, C., Liu, J., Baker, A., Colburn, N. H., & Yang, H.-S. (2017) · Oncogene

PI3K/AKT/mTOR signaling in cancerMechanisms of cancer metastasis

Cited by 67

Aerosol-delivered programmed cell death 4 enhanced apoptosis, controlled cell cycle and suppressed AP-1 activity in the lungs of AP-1 luciferase reporter mice

Hwang, S.-K., Jin, H., Kwon, J. T., Chang, S.-H., Kim, T. H., Cho, C.-S., Lee, K. H., Young, M. R., Colburn, N. H., Beck, G. R., et al. (2007) · Gene Therapy

RNA Interference and Gene DeliveryInhalation and Respiratory Drug Delivery

Cited by 44

AKT Activation by Pdcd4 Knockdown Up-Regulates Cyclin D1 Expression and Promotes Cell Proliferation

Guo, X., Li, W., Wang, Q., & Yang, H.-S. (2011) · Genes & Cancer

NF-κB Signaling PathwaysSignaling Pathways in Disease

Cited by 40