Zhang, Zhentao

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

Zhang, Z., Song, M., Liu, X., Kang, S. S., Kwon, I.-S., Duong, D. M., Seyfried, N. T., Hu, W. T., Liu, Z., Wang, J.-Z., et al. (2014) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 494

7,8-Dihydroxyflavone Prevents Synaptic Loss and Memory Deficits in a Mouse Model of Alzheimer’s Disease

Zhang, Z., Liu, X., Schroeder, J. P., Chan, C.-B., Song, M., Yu, S. P., Weinshenker, D., & Ye, K. (2014) · Neuropsychopharmacology

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 242

Tau accelerates α-synuclein aggregation and spreading in Parkinson’s disease

Pan, L., Li, C., Meng, L., Tian, Y., He, M., Yuan, X., Zhang, G., Zhang, Z., Xiong, J., Chen, G., et al. (2022) · Brain

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 154

Exosome-mediated delivery of antisense oligonucleotides targeting α-synuclein ameliorates the pathology in a mouse model of Parkinson's disease

Yang, J., Luo, S., Zhang, J., Yu, T., Fu, Z., Zheng, Y., Xu, X., Liu, C., Fan, M., & Zhang, Z. (2021) · Neurobiology of Disease

Parkinson's Disease Mechanisms and TreatmentsExtracellular vesicles in disease

Cited by 152

Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer’s disease

Zhang, Z., Obianyo, O., Dall, E., Du, Y., Fu, H., Liu, X., Kang, S. S., Song, M., Yu, S.-P., Cabrele, C., et al. (2017) · Nature Communications

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 146

Reactive microglia enhance the transmission of exosomal α-synuclein via toll-like receptor 2

Xia, Y., Zhang, G., Kou, L., Yin, S., Han, C., Hu, J., Wan, F., Sun, Y., Wu, J., Li, Y., et al. (2021) · Brain

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 123

TREM2 ectodomain and its soluble form in Alzheimer’s disease

Yang, J., Fu, Z., Zhang, X., Xiong, M., Meng, L., & Zhang, Z. (2020) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 113

Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology

Blennow, K., Chen, C., Cicognola, C., Wildsmith, K. R., Manser, P. T., Bohorquez, S. M. S., Zhang, Z., Xie, B., Peng, J., Hansson, O., et al. (2020) · Brain

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 105

Dysfunction of Synaptic Vesicle Endocytosis in Parkinson’s Disease

Zou, L., Tian, Y., & Zhang, Z. (2021) · Frontiers in Integrative Neuroscience

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 44

Suppression of abnormal α-synuclein expression by activation of BDNF transcription ameliorates Parkinson’s disease-like pathology

Cao, Q., Luo, S., Yao, W., Qu, Y., Wang, N., Hong, J., Murayama, S., Zhang, Z., Chen, J., Hashimoto, K., et al. (2022) · Molecular Therapy - Nucleic Acids

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 41

C/EBPβ/AEP Signaling Drives Alzheimer’s Disease Pathogenesis

Xiong, J., Zhang, Z., & Ye, K. (2023) · Neuroscience Bulletin

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 37

ApoE3 R136S binds to Tau and blocks its propagation, suppressing neurodegeneration in mice with Alzheimer’s disease

Chen, G., Wang, M., Zhang, Z., Hong, D. K., Ahn, E. H., Liu, X., Kang, S. S., & Ye, K. (2025) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 21

Chronic stress induces depression-like behaviors and Parkinsonism via upregulating α-synuclein

Xia, D., Xiong, M., Yang, Y., Wang, X., Chen, Q., Li, S., Meng, L., & Zhang, Z. (2025) · npj Parkinson's Disease

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 15