Nguyen, Minh N.

In vivo evidence for a novel pathway of vitamin D 3 metabolism initiated by P450scc and modified by CYP27B1

Slominski, A. T., Kim, T., Shehabi, H. Z., Semak, I., Tang, E. K. Y., Nguyen, M. N., Benson, H. A. E., Korik, E., Janjetovic, Z., Chen, J., et al. (2012) · The FASEB Journal

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 266

Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity

Slominski, A. T., Janjetovic, Z., Fuller, B. E., Zmijewski, M. A., Tuckey, R. C., Nguyen, M. N., Sweatman, T., Li, W., Zjawiony, J., Miller, D., et al. (2010) · PLoS ONE

Vitamin D Research StudiesRetinoids in leukemia and cellular processes

Cited by 149

20-Hydroxycholecalciferol, Product of Vitamin D3 Hydroxylation by P450scc, Decreases NF-κB Activity by Increasing IκBα Levels in Human Keratinocytes

Janjetovic, Z., Zmijewski, M. A., Tuckey, R. C., DeLeon, D. A., Nguyen, M. N., Pfeffer, L. M., & Slominski, A. T. (2009) · PLoS ONE

NF-κB Signaling PathwaysVitamin D Research Studies

Cited by 130

20-Hydroxyvitamin D3, a product of vitamin D3 hydroxylation by cytochrome P450scc, stimulates keratinocyte differentiation

Zbytek, B., Janjetovic, Z., Tuckey, R. C., Zmijewski, M. A., Sweatman, T. W., Jones, E., Nguyen, M. N., & Slominski, A. T. (2008) · Journal of Investigative Dermatology

Vitamin D Research StudiesSkin and Cellular Biology Research

Cited by 118

Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc

Tuckey, R. C., Li, W., Zjawiony, J. K., Zmijewski, M. A., Nguyen, M. N., Sweatman, T., Miller, D., & Slominski, A. (2008) · The FEBS Journal

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 118

20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells

Slominski, A. T., Kim, T.-K., Janjetovic, Z., Tuckey, R. C., Bieniek, R., Yue, J., Li, W., Chen, J., Nguyen, M. N., Tang, E. K. Y., et al. (2011) · American Journal of Physiology-Cell Physiology

Vitamin D Research StudiesSkin Protection and Aging

Cited by 113

20,23‐dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF‐κB activity in human keratinocytes

Janjetovic, Z., Tuckey, R. C., Nguyen, M. N., Thorpe, E. M., & Slominski, A. T. (2010) · Journal of Cellular Physiology

Vitamin D Research StudiesPsoriasis: Treatment and Pathogenesis

Cited by 103

High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives

Janjetovic, Z., Brozyna, A. A., Tuckey, R. C., Kim, T.-K., Nguyen, M. N., Jozwicki, W., Pfeffer, S. R., Pfeffer, L. M., & Slominski, A. T. (2011) · British Journal of Cancer

NF-κB Signaling PathwaysVitamin D Research Studies

Cited by 91

20 S-Hydroxyvitamin D3, Noncalcemic Product of CYP11A1 Action on Vitamin D3, Exhibits Potent Antifibrogenic Activity in Vivo

Slominski, A., Janjetovic, Z., Tuckey, R. C., Nguyen, M. N., Bhattacharya, K. G., Wang, J., Li, W., Jiao, Y., Gu, W., Brown, M., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism

Systemic Sclerosis and Related DiseasesVitamin D Research Studies

Cited by 89

Production of 22-hydroxy metabolites of vitamin D3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cells

Tuckey, R. C., Li, W., Shehabi, H. Z., Janjetovic, Z., Nguyen, M. N., Kim, T.-K., Chen, J., Howell, D. E., Benson, H. A. E., Sweatman, T., et al. (2011) · Drug Metabolism and Disposition

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 88

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes

Slominski, A. T., Kim, T.-K., Chen, J., Nguyen, M. N., Li, W., Yates, C. R., Sweatman, T., Janjetovic, Z., & Tuckey, R. C. (2012) · The International Journal of Biochemistry & Cell Biology

Steroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

Cited by 81

Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics.

Chan, D. C., Watts, G. F., Nguyen, M. N., & Barrett, P. H. R. (2006) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 70

Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength

Kim, T.-K., Wang, J., Janjetovic, Z., Chen, J., Tuckey, R. C., Nguyen, M. N., Tang, E. K. Y., Miller, D., Li, W., & Slominski, A. T. (2012) · Molecular and Cellular Endocrinology

Vitamin D Research StudiesRetinoids in leukemia and cellular processes

Cited by 67

Metabolism of vitamin D2 to 17, 20,24-trihydroxyvitamin D2 by cytochrome p450scc (CYP11A1)

Nguyen, M. N., Slominski, A., Li, W., Ng, Y. R., & Tuckey, R. C. (2009) · Drug Metabolism and Disposition

Vitamin D Research StudiesSteroid Chemistry and Biochemistry

Cited by 48

Metabolism of 1α-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1α,20-dihydroxyvitamin D3

Tuckey, R. C., Janjetovic, Z., Li, W., Nguyen, M. N., Zmijewski, M. A., Zjawiony, J., & Slominski, A. (2008) · The Journal of Steroid Biochemistry and Molecular Biology

Vitamin D Research StudiesPharmacogenetics and Drug Metabolism

Cited by 48

Rat CYP24A1 acts on 20-hydroxyvitamin D3 producing hydroxylated products with increased biological activity

Tieu, E. W., Tang, E. K. Y., Chen, J., Li, W., Nguyen, M. N., Janjetovic, Z., Slominski, A., & Tuckey, R. C. (2012) · Biochemical Pharmacology

Vitamin D Research StudiesPharmacogenetics and Drug Metabolism

Cited by 44

Purified Mouse CYP27B1 Can Hydroxylate 20,23-Dihydroxyvitamin D3, Producing 1α,20,23-Trihydroxyvitamin D3, Which Has Altered Biological Activity

Tang, E. K. Y., Li, W., Janjetovic, Z., Nguyen, M. N., Wang, Z., Slominski, A., & Tuckey, R. C. (2010) · Drug Metabolism and Disposition

Vitamin D Research StudiesPharmacogenetics and Drug Metabolism

Cited by 40

Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol

Tuckey, R. C., Nguyen, M. N., Chen, J., Slominski, A. T., Baldisseri, D. M., Tieu, E. W., Zjawiony, J. K., & Li, W. (2012) · Drug Metabolism and Disposition

Steroid Chemistry and BiochemistryMetal-Catalyzed Oxygenation Mechanisms

Cited by 32