Apolipoproteins C-III and A-V as predictors of very-low-density lipoprotein triglyceride and apolipoprotein B-100 kinetics.
Abstract
OBJECTIVE: We investigated the associations between plasma very-low-density lipoprotein (VLDL)-apolipoprotein (apo)C-III and apoA-V concentrations and the kinetics of VLDL-apoB-100 and VLDL triglycerides in 15 men. We also explored the relationship between these parameters of VLDL metabolism and VLDL-apoC-III kinetics. METHODS AND RESULTS: ApoC-III, apoB, and triglyceride kinetics in VLDL were determined using stable isotopes and multicompartmental modeling to estimate production rate (PR) and fractional catabolic rate (FCR). Plasma VLDL-apoC-III concentration was significantly and inversely associated with the FCRs of VLDL triglycerides (r=-0.610) and VLDL-apoB (r=-0.791), and positively correlated with the PR of VLDL-apoC-III (r=0.842). However, apoA-V concentration was not significantly associated with any of the kinetic variables. There was a significant association (P<0.01) between the PRs of VLDL triglycerides and VLDL-apoB (r=0.641), and between the FCRs of VLDL triglycerides and VLDL-apoB (r=0.737). In multiple regression analysis, plasma VLDL-apoC-III concentration was a significant predictor of VLDL triglyceride FCR (beta-coefficient=-0.575) and VLDL-apoB FCR (beta-coefficient=-0.839). CONCLUSIONS: Our findings suggest that increased VLDL-apoC-III concentrations resulting from an overproduction of VLDL-apoC-III are strongly associated with the delayed catabolism of triglycerides and apoB in VLDL. We also demonstrated that the kinetics of VLDL triglycerides and apoB are closely coupled. Our data do not support a role for plasma apoA-V in regulating VLDL kinetics.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Clearance of VLDL from the circulation is reduced in many patients with hypertriglyceridemia, in part due to saturation of triglyceride clearance.
“Clearance of VLDL from the circulation is reduced in many patients with hypertriglyceridemia (64, 65, 73), in part due to saturation of triglyceride clearance (74).”
From Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline (2012) · cites this paper as [73]
The Discussion (page unavailable) reports that higher VLDL-apoC-III predicted delayed catabolism of VLDL triglycerides and apoB in men with mild dyslipidemia. It does not establish reduced VLDL clearance in many patients with hypertriglyceridemia; the authors say they did not study severe hypertriglyceridemia. The separate saturation explanation is attached to citation 74, not this source. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502 · see citing works
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Lemieux, I., Pascot, A., Couillard, C., Lamarche, B., Tchernof, A., Alméras, N., Bergeron, J., Gaudet, D., Tremblay, G., Prud’homme, D., et al. (2000) · Circulation · doi:10.1161/01.cir.102.2.179 · Cited by 937 · see citing works
Hypertriglyceridemia as a Result of Human apo <i>CII</i> Gene Expression in Transgenic Mice
Ito, Y., Azrolan, N., O'Connell, A., Walsh, A., & Breslow, J. L. (1990) · Science · doi:10.1126/science.2167514 · Cited by 539 · see citing works
Sacks, F. M., Alaupovic, P., Moye, L. A., Cole, T. G., Sussex, B., Stampfer, M. J., Pfeffer, M. A., & Braunwald, E. (2000) · Circulation · doi:10.1161/01.cir.102.16.1886 · Cited by 490 · see citing works
Schaap, F. G., Rensen, P. C. N., Voshol, P. J., Vrins, C. L. J., van der Vliet, H. N., Chamuleau, R. A. F. M., Havekes, L. M., Groen, A. K., & van Dijk, K. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403240200 · Cited by 300 · see citing works
Merkel, M., Loeffler, B., Kluger, M. A., Fabig, N., Geppert, G., Pennacchio, L. A., Laatsch, A., & Heeren, J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m411412200 · Cited by 292 · see citing works
Apolipoproteins C-I and C-III as important modulators of lipoprotein metabolism
Shachter, N. S. (2001) · Current Opinion in Lipidology · doi:10.1097/00041433-200106000-00009 · Cited by 288 · see citing works
Overproduction of VLDL 1 Driven by Hyperglycemia Is a Dominant Feature of Diabetic Dyslipidemia
Adiels, M., Borén, J., CASLAKE, M. J., Stewart, P., Soro, A., Westerbacka, J., Wennberg, B., Olofsson, S., Packard, C. J., & Taskinen, M. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000172689.53992.25 · Cited by 269 · see citing works
O'Brien, P. J., Alborn, W. E., Sloan, J. H., Ulmer, M., Boodhoo, A., Knierman, M. D., Schultze, A. E., & Konrad, R. J. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2004.040824 · Cited by 215 · see citing works
Vu‐Dac, N., Gervois, P. P., Jäkel, H., Nowak, M., Baugé, E., Dehondt, H., Staels, B., Pennacchio, L. A., Rubin, E. M., Fruchart‐Najib, J., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212191200 · Cited by 206 · see citing works
Cohn, J. S., Patterson, B. W., Uffelman, K. D., Davignon, J., & Steiner, G. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032056 · Cited by 170 · see citing works
Pennacchio, L. A., & Rubin, E. M. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000054194.78240.45 · Cited by 168 · see citing works
Willems van Dijk, K., Rensen, P. C., Voshol, P. J., & Havekes, L. M. (2004) · Current Opinion in Lipidology · doi:10.1097/00041433-200406000-00002 · Cited by 154 · see citing works
The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk
Lai, C., Parnell, L. D., & Ordovás, J. M. (2005) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000162320.54795.68 · Cited by 137 · see citing works
Jong, M. C., Rensen, P. C. N., Dahlmans, V. E. H., van der Boom, H., van Berkel, T. J. C., & Havekes, L. M. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32211-2 · Cited by 136 · see citing works
Raspé, E., Duez, H., Gervois, P., Fiévet, C., Fruchart, J., Besnard, S., Mariani, J., Tedgui, A., & Staels, B. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m004982200 · Cited by 134 · see citing works
Chan, D. C., Watts, G. F., Redgrave, T. G., Mori, T. A., & Barrett, P. H. R. (2002) · Metabolism · doi:10.1053/meta.2002.33339 · Cited by 133 · see citing works
Self-citationGrosskopf, I., Baroukh, N., Lee, S., Kamari, Y., Harats, D., Rubin, E. M., Pennacchio, L. A., & Cooper, A. D. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000186189.26141.12 · Cited by 128 · see citing works
Riches, F. M., Watts, G. F., Naoumova, R. P., Kelly, J., Croft, K. D., & Thompson, G. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800602 · Cited by 126 · see citing works
Self-citationTriglyceride-rich lipoproteins and the progression of coronary artery disease
Hodis, H. N., & Mack, W. J. (1995) · Current Opinion in Lipidology · doi:10.1097/00041433-199508000-00004 · Cited by 118 · see citing works
Adiels, M., Packard, C. J., CASLAKE, M. J., Stewart, P., Soro, A., Westerbacka, J., Wennberg, B., Olofsson, S., Taskinen, M., & Borén, J. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m400108-jlr200 · Cited by 117 · see citing works
Markers of triglyceride-rich lipoprotein remnant metabolism in visceral obesity
Chan, D. C., Watts, G. F., Barrett, P. H., Mamo, J. C., & Redgrave, T. G. (2002) · Clinical Chemistry · doi:10.1093/clinchem/48.2.278 · Cited by 117 · see citing works
Self-citationA sandwich enzyme-linked immunosorbent assay for human plasma apolipoprotein A-V concentration
Ishihara, M., Kujiraoka, T., Iwasaki, T., Nagano, M., Takano, M., Ishii, J., Tsuji, M., Ide, H., Miller, I. P., Miller, N. E., et al. (2005) · Journal of Lipid Research · doi:10.1194/jlr.d500018-jlr200 · Cited by 97 · see citing works
Huff, M. W., Fidge, N., Nestel, P. J., Billington, T., & Watson, B. (1981) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37316-8 · Cited by 90 · see citing works
Increased apoC-III production is a characteristic feature of patients with hypertriglyceridemia
Cohn, J. S., Tremblay, M., Batal, R., Jacques, H., Rodriguez, C., Steiner, G. A., Mamer, O., & Davignon, J. (2004) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2004.06.011 · Cited by 62 · see citing works
Transcriptional Regulation of Apolipoprotein A5 Gene Expression by the Nuclear Receptor RORα
Genoux, A., Dehondt, H., Helleboid‐Chapman, A., Duhem, C., Hum, D. W., Martin, G., Pennacchio, L. A., Staels, B., Fruchart‐Najib, J., & Fruchart, J. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000163841.85333.83 · Cited by 54 · see citing works
Chan, D. C., Barrett, P. H. R., & Watts, G. F. (2004) · Clinical Science · doi:10.1042/cs20040109 · Cited by 44 · see citing works
Self-citationHuff, M. W., & Nestel, P. J. (1982) · Metabolism · doi:10.1016/0026-0495(82)90240-2 · Cited by 43 · see citing works
Dwyer, K. P., Barrett, P. H. R., Chan, D. C., Foo, J. I., Watts, G. F., & Croft, K. D. (2002) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30177-2 · Cited by 39 · see citing works
Self-citationTobin, G. J., Nagashima, K., & Gonda, M. A. (1996) · Methods · doi:10.1006/meth.1996.0096 · Cited by 36 · see citing works
Postprandial increase of plasma apoAV concentrations in Type 2 diabetic patients
Pruneta‐Deloche, V., Ponsin, G., Groisne, L., Fruchart‐Najib, J., Lagarde, M., & Moulin, P. (2005) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2005.01.034 · Cited by 35 · see citing works
Olofsson, S. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000167518.27125.b1 · Cited by 22 · see citing works
Barrett, P. H. R., Baker, N., & Nestel, P. J. (1991) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42027-9 · Cited by 22 · see citing works
Self-citation[12] Immunochemical methods for quantification of human apolipoprotein C-III
Kashyap, M. L. (1996) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(96)63014-6 · Cited by 3 · see citing works
Flagged first, then by citations
Research works printed but not linked: 5
- Chan DC, Watts GF, Redgrave TG, Mori TA, Barrett PHR. Apoli- poprotein B100 kinetics in visceral obesity: associations with plasma apolipoprotein CIII concentrations. Metabolism. 2002;51:1041-1046.
- Olofsson SO. ApoA-V: The regulation of a regulator of plasma triglyc- erides. Arterioscler Thromb Vasc Biol. 2005;25:1097-1099.
- Dwyer K, Barrett PHR, Chan D, Foo JI, Watts GF, Croft KD. Oxazo- linone derivatives of amino acids and gas chromatography-mass spec- trometry: femtogram sensitivity applied to stable isotope kinetic studies of lipoproteins. J Lipid Res. 2002;43:344 -349.
- Adiels M, Boren J, Caslake MJ, Stewart P, Soro A, Westerbacka J, Wennberg B, Olofsson SO, Packard C, Taskinen MR. Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dys- lipidemia. Arterioscler Thromb Vasc Biol. 2005;25:1697-1703.
- Ito Y, Azrolan N, O'Connell A, Walsh A, Breslow JL. Hypertriglyceri- demia as a result of human apo CIII gene expression in transgenic mice. Science. 1990;249:790 -793.
Cited by
Sorted by citations
Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline
Berglund, L., Brunzell, J. D., Goldberg, A. C., Goldberg, I. J., Sacks, F., Murad, M. H., & Stalenhoef, A. F. H. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3213 · Cited by 887 · see citing works
“Clearance of VLDL from the circulation is reduced in many patients with hypertriglyceridemia (64, 65, 73), in part due to saturation of triglyceride clearance (74).”
Adiels, M., Olofsson, S.-O., Taskinen, M.-R., & Borén, J. (2008) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.107.160192 · Cited by 820 · see citing works
Fruchart, J.-C., Sacks, F., Hermans, M. P., Assmann, G., Brown, W. V., Ceska, R., Chapman, M. J., Dodson, P. M., Fioretto, P., Ginsberg, H. N., et al. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.10.002 · Cited by 463 · see citing works
Zheng, C., Khoo, C., Furtado, J., & Sacks, F. M. (2010) · Circulation · doi:10.1161/circulationaha.109.875807 · Cited by 223 · see citing works
Apolipoprotein C-III: from pathophysiology to pharmacology
Norata, G. D., Tsimikas, S., Pirillo, A., & Catapano, A. L. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.07.001 · Cited by 182 · see citing works
Adiels, M., Olofsson, S., Taskinen, M., & Borén, J. (2006) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000226115.97436.c0 · Cited by 171 · see citing works
Sundaram, M., Zhong, S., Khalil, M. B., Links, P. H., Zhao, Y., Iqbal, J., Hussain, M. M., Parks, R. J., Wang, Y., & Yao, Z. (2009) · Journal of Lipid Research · doi:10.1194/m900346-jlr200 · Cited by 170 · see citing works
Sacks, F. M. (2015) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000146 · Cited by 168 · see citing works
Morita, S. (2015) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b15-00716 · Cited by 156 · see citing works
Hypertriglyceridemia in the genomic era: a new paradigm
Lewis, G. F., Xiao, C., & Hegele, R. A. (2015) · Endocrine Reviews · doi:10.1210/er.2014-1062 · Cited by 152 · see citing works
Apolipoprotein A-V; a potent triglyceride reducer
Nilsson, S. K., Heeren, J., Olivecrona, G., & Merkel, M. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.07.019 · Cited by 115 · see citing works
Khetarpal, S. A., Zeng, X., Millar, J. S., Vitali, C., Somasundara, A. V. H., Zanoni, P., Landro, J. A., Barucci, N., Zavadoski, W. J., Sun, Z., et al. (2017) · Nature Medicine · doi:10.1038/nm.4390 · Cited by 109 · see citing works
Chunyu, Z., Christina, K., Katsunori, I., & Sacks, F. M. (2007) · Journal of Lipid Research · doi:10.1194/jlr.p600011-jlr200 · Cited by 95 · see citing works
An ABC of apolipoprotein C-III: a clinically useful new cardiovascular risk factor?
Chan, D. C., Chen, M. M., Ooi, E. M. M., & Watts, G. F. (2008) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2007.01678.x · Cited by 85 · see citing works
Self-citationPlasma apolipoprotein A5 and triglycerides in type 2 diabetes
on behalf of the DALI study group, Dallinga‐Thie, G. M., van Tol, A., Hattori, H., der Zee, L. C. V. V., Jansen, H., & Sijbrands, E. J. G. (2006) · Diabetologia · doi:10.1007/s00125-006-0261-0 · Cited by 87 · see citing works
The role of hypertriglyceridemia in atherosclerosis
Le, N., & Walter, M. F. (2007) · Current Atherosclerosis Reports · doi:10.1007/s11883-007-0006-7 · Cited by 79 · see citing works
Borén, J., Watts, G. F., Adiels, M., Söderlund, S., Chan, D. C., Hakkarainen, A., Lundbom, J., Lundbom, N., Matikainen, N., Kahri, J., et al. (2015) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.115.305614 · Cited by 72 · see citing works
Self-citationHiukka, A., Leinonen, E., Jauhiainen, M., Sundvall, J., Ehnholm, C., Keech, A. C., & Taskinen, M. R. (2007) · Diabetologia · doi:10.1007/s00125-007-0751-8 · Cited by 68 · see citing works
Chan, D. C., Barrett, P. H. R., Ooi, E. M. M., Ji, J., Chan, D. T., & Watts, G. F. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1457 · Cited by 66 · see citing works
Self-citationExploring apolipoprotein C-III: pathophysiological and pharmacological relevance
Packard, C. J., Pirillo, A., Tsimikas, S., Ference, B. A., & Catapano, A. L. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvad177 · Cited by 65 · see citing works
Chan, D. C., Nguyen, M. N., Watts, G. F., & Barrett, P. H. R. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2676 · Cited by 62 · see citing works
Self-citationChan, D. C., Watts, G. F., Gan, S. K., Wong, A. T. Y., Ooi, E. M. M., & Barrett, P. H. R. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.202275 · Cited by 57 · see citing works
Self-citationPavlic, M., Valéro, R., Duez, H., Xiao, C., Szeto, L., Patterson, B. W., & Lewis, G. F. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.108.169383 · Cited by 52 · see citing works
Harvey, S. B., Zhang, Y., Wilson‐Grady, J., Monkkonen, T., Nelsestuen, G. L., Kasthuri, R. S., Verneris, M. R., Lund, T. C., Ely, E. W., Bernard, G. R., et al. (2008) · Journal of Proteome Research · doi:10.1021/pr800751x · Cited by 43 · see citing works
Rare APOA5 mutations—Clinical consequences, metabolic and functional effects
Talmud, P. J. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.12.010 · Cited by 42 · see citing works
Shin, M., & Krauss, R. M. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.02.025 · Cited by 40 · see citing works
Clinical significance of apolipoprotein A5
Tai, E. S., & Ordovás, J. M. (2008) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328304b681 · Cited by 40 · see citing works
The metabolic and pharmacologic bases for treating atherogenic dyslipidaemia
Chan, D. C., Barrett, P. H. R., & Watts, G. F. (2013) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2013.10.001 · Cited by 40 · see citing works
Self-citationHigh-density lipoprotein and transport of cholesterol and triglyceride in blood
Brown, W. V. (2007) · Journal of clinical lipidology · doi:10.1016/j.jacl.2007.02.001 · Cited by 39 · see citing works
The ins (cell) and outs (plasma) of apolipoprotein A-V
Forte, T. M., Shu, X., & Ryan, R. O. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800050-jlr200 · Cited by 38 · see citing works
Wong, A. T. Y., Chan, D. C., Pang, J., Watts, G. F., & Barrett, P. H. R. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2477 · Cited by 38 · see citing works
Self-citationLoganin inhibits the inflammatory response in mouse 3T3L1 adipocytes and mouse model
Li, Y., Li, Z., Shi, L., Zhao, C., Shen, B., Tian, Y., & Feng, H. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.04.026 · Cited by 38 · see citing works
Apolipoprotein profiling as a personalized approach to the diagnosis and treatment of dyslipidaemia
Renee Ruhaak, L., van der Laarse, A., & Cobbaert, C. M. (2019) · Annals of Clinical Biochemistry: International Journal of Laboratory Medicine · doi:10.1177/0004563219827620 · Cited by 38 · see citing works
Ouatou, S., Ajjemami, M., Charoute, H., Sefri, H., Ghalim, N., Rhaissi, H., Benrahma, H., Barakat, A., & Rouba, H. (2014) · Lipids in Health and Disease · doi:10.1186/1476-511x-13-60 · Cited by 34 · see citing works
Charrière, S., Bernard, S., Aqallal, M., Merlin, M., Billon, S., Perrot, L., Coquil, É. L., Sassolas, A., Moulin, P., & Marçais, C. (2008) · Clinica Chimica Acta · doi:10.1016/j.cca.2008.04.013 · Cited by 31 · see citing works
Hopkins, P. N., Nanjee, M. N., Wu, L. L., McGinty, M. G., Brinton, E. A., Hunt, S. C., & Anderson, J. L. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.05.016 · Cited by 29 · see citing works
Li, D., Rodia, C. N., Johnson, Z. K., Bae, M., Muter, A., Heussinger, A. E., Tambini, N. S., Longo, A. M., Dong, H., Lee, J., et al. (2019) · Journal of Lipid Research · doi:10.1194/jlr.m092460 · Cited by 29 · see citing works
Abe, Y., Kawakami, A., Osaka, M., Uematsu, S., Akira, S., Shimokado, K., Sacks, F. M., & Yoshida, M. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.210427 · Cited by 26 · see citing works
RetractedThe Pathogenic Role of Very Low Density Lipoprotein on Atrial Remodeling in the Metabolic Syndrome
Lee, H., & Lin, Y. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030891 · Cited by 25 · see citing works
Nguyen, M. N., Chan, D. C., Dwyer, K. P., Bolitho, P., Watts, G. F., & Barrett, P. H. R. (2006) · Journal of Lipid Research · doi:10.1194/jlr.m600018-jlr200 · Cited by 23 · see citing works
Self-citationLamon‐Fava, S., Herrington, D. M., Horvath, K. V., Schaefer, E. J., & Asztalos, B. F. (2010) · Metabolism · doi:10.1016/j.metabol.2010.05.012 · Cited by 22 · see citing works
van Schalkwijk, D. B., de Graaf, A. A., van Ommen, B., van Bochove, K., Rensen, P. C. N., Havekes, L. M., van de Pas, N. C. A., Hoefsloot, H. C. J., van der Greef, J., & Freidig, A. P. (2009) · Journal of Lipid Research · doi:10.1194/jlr.m800354-jlr200 · Cited by 21 · see citing works
Wong, A. T. Y., Chan, D. C., Ooi, E. M. M., Ng, T. W., Watts, G. F., & Barrett, P. H. R. (2013) · Clinical Science · doi:10.1042/cs20120587 · Cited by 20 · see citing works
Self-citationAPOC3 Protein Is Not a Predisposing Factor for Fat-induced Nonalcoholic Fatty Liver Disease in Mice
Cheng, X., Yamauchi, J., Lee, S., Zhang, T., Gong, Z., Muzumdar, R. H., Qu, S., & Dong, H. H. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.765917 · Cited by 20 · see citing works
Kahri, J., Fruchart‐Najib, J., Matikainen, N., Fruchart, J., Vakkilainen, J., & Taskinen, M. (2007) · Diabetes Care · doi:10.2337/dc07-0100 · Cited by 18 · see citing works
Sips, F. L. P., Tiemann, C. A., Oosterveer, M. H., Groen, A. K., Hilbers, P. A. J., & van Riel, N. A. W. (2014) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003579 · Cited by 16 · see citing works
Ng, T., Ooi, E. M. M., Watts, G. F., Chan, D. C., & Barrett, P. H. R. (2013) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12243 · Cited by 15 · see citing works
Self-citationvan den Berg, S. A. A., Heemskerk, M. M., Geerling, J. J., van Klinken, J. B., Schaap, F. G., Bijland, S., Berbée, J. F. P., van Harmelen, V., Pronk, A. C. M., Schreurs, M., et al. (2013) · The FASEB Journal · doi:10.1096/fj.12-225367 · Cited by 15 · see citing works
Mutation Screening of the APOA5 Gene in Subjects with Coronary Artery Disease
Soufi, M., Sattler, A., Kurt, B., & Schaefer, J. R. (2012) · Journal of Investigative Medicine · doi:10.2310/jim.0b013e3182686918 · Cited by 15 · see citing works
Morita, S., Sakurai, A., Nakano, M., Kitagawa, S., & Handa, T. (2010) · Lipids · doi:10.1007/s11745-010-3498-9 · Cited by 15 · see citing works
Watts, G. F., Chan, D. C., Ooi, E., Nestel, P., Beilin, L. J., & Barrett, P. H. R. (2006) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2006.04458.x · Cited by 14 · see citing works
Self-citationFilippatos, T. D., Tsimihodimos, V., Kostapanos, M. S., Kostara, C. E., Bairaktari, E. T., Kiortsis, D. N., Tselepis, A. D., & Elisaf, M. (2008) · Cited by 14 · see citing works
Effect of Hypertriglyceridemia on Beta Cell Mass and Function in ApoC3 Transgenic Mice
Liu, Y., Cheng, X., Zhang, T., Lee, S., Yamauchi, J., Xiao, X., Gittes, G. K., Qu, S., Jiang, C., & Dong, H. H. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.707885 · Cited by 14 · see citing works
Hypertriglyceridemia Associated With Abdominal Obesity
Carpentier, A. C. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.306412 · Cited by 12 · see citing works
Desroches, S., Ruel, I. L., Deshaies, Y., Paradis, M.-E., Archer, W. R., Couture, P., Bergeron, N., & Lamarche, B. (2007) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602673 · Cited by 9 · see citing works
Chan, D. C., Pang, J., & Watts, G. F. (2016) · Springer eBooks · doi:10.1007/978-3-319-11251-0_30 · Cited by 8 · see citing works
Self-citationLipid Metabolism in Metabolic Syndrome
Borén, J., & Adiels, M. (2013) · Springer eBooks · doi:10.1007/978-3-319-01008-3_8 · Cited by 6 · see citing works
Kim, D. H., Lee, S., Noh, S. G., Lee, J., & Chung, H. Y. (2024) · Aging · doi:10.18632/aging.205610 · Cited by 6 · see citing works
Yan, Y., Deng, H., Jian, L., Su, Y., Li, Y., & Mi, G.-P. (2012) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-012-0102-2 · Cited by 4 · see citing works
Chan, D. C., Pang, J., & Watts, G. F. (2015) · Springer eBooks · doi:10.1007/978-3-319-12125-3_30-1 · Cited by 5 · see citing works
Self-citationRole of growth hormone in hepatic and intestinal triglyceride-rich lipoprotein metabolism
Maraninchi, M., Calabrese, A., Nogueira, J. P., Castinetti, F., Mancini, J., Mourre, F., Pietri, L., Benamo, E., Albarel, F., Morange, I., et al. (2021) · Journal of clinical lipidology · doi:10.1016/j.jacl.2021.08.003 · Cited by 4 · see citing works
The forkhead box O family in insulin action and lipid metabolism
Lee, S., Zhu, C., Yamauchi, J., Zhu, P., Feng, X., Qu, S., & Dong, H. H. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819404-1.00013-0 · Cited by 3 · see citing works
Yamauchi, J., Kim, D. H., & Dong, H. H. (2017) · Springer eBooks · doi:10.1007/978-3-319-67199-4_634 · Cited by 3 · see citing works
Ersonified diagnostic and correction dyslipidemia approach by profiling of apolipoproteins
Kachkovsky, M. A., Vvedenskaya, I. P., Vvedensky, V. Y., Supilnikov, A. A., Ponomareva, J. V., & Milyakova, M. N. (2020) · Bulletin of the Medical Institute REAVIZ (REHABILITATION DOCTOR AND HEALTH) · doi:10.20340/vmi-rvz.2020.4.11 · Cited by 1 · see citing works
Apolipoprotein Gene Structure and Function
Martín-Campos, J. M., Chang, B. H.-J., Blanco‐Vaca, F., Chan, L., & Julve, J. (2017) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0005909.pub3 · Cited by 1 · see citing works
Cugat, K. U. (2007) · TDX (Tesis Doctorals en Xarxa)
Novel factors affecting clearance of triacylglycerol-rich lipoproteins from blood
Nilsson, S. K. (2010)
Running title: Postprandial apoA-V in type 2 diabetes
Kahri, J., Fruchart-Najib, J., Matikainen, N., Fruchart, J., Vakkilainen, J., & Taskinen, M. (2007)
Apolipoprotein Gene Structure and Function
Huey, P. U., Chang, B. H.-J., & Chan, L. (2007) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0005909.pub2
Yamauchi, J., Kim, D. H., & Dong, H. H. (2016) · Springer eBooks · doi:10.1007/978-1-4614-6438-9_634-1
- Authors
- Chan, D. C., Watts, G. F., Nguyen, M. N., & Barrett, P. H. R.
- Affiliations
- The University of Western Australia (AU)
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2006-03
- Volume
- 26
- Issue
- 3
- Pages
- 590-596
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2027083746
- Cited by
- 70
- References
- 36
- Citations by year
- 2024: 1 · 2023: 1 · 2021: 1 · 2020: 3 · 2019: 2 · 2017: 4 · 2016: 4 · 2015: 6 · 2014: 3 · 2013: 6 · 2012: 3
- FWCI
- 6.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Arteriosclerosis Thrombosis and Vascular Biology (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Funders
- Pfizer
- Royal Perth Hospital Medical Research Foundation
- Raine Medical Research Foundation
- Medical Research Council
- National Health and Medical Research Council
- National Institute of Biomedical Imaging and Bioengineering (P41EB001975)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
- Keywords
- apolipoprotein C-III, apolipoprotein A-V, VLDL, VLDL triglycerides, apolipoprotein B-100, lipoprotein kinetics, fractional catabolic rate, production rate, triglyceride catabolism, stable isotope tracers
- MeSH terms
- Apolipoprotein A-V, Aged, Apolipoproteins, Apolipoproteins A, Apolipoproteins B, Apolipoproteins C, Homeostasis, Humans, Leucine, Male, Middle Aged, Predictive Value of Tests, Regression Analysis, Triglycerides, Hypertriglyceridemia, Cholesterol, VLDL, Apolipoprotein B-100, Apolipoprotein C-III
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review