Zhang, Bo

Integrative analysis of 111 reference human epigenomes

Roadmap Epigenomics Consortium, Kundaje, A., Meuleman, W., Ernst, J., Bilenky, M., Yen, A., Heravi-Moussavi, A., Kheradpour, P., Zhang, Z., Wang, J., et al. (2015) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

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DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

Brocks, D., Schmidt, C. R., Daskalakis, M., Jang, H. S., Shah, N. M., Li, D., Li, J., Zhang, B., Hou, Y., Laudato, S., et al. (2017) · Nature Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

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Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

Petralia, F., Tignor, N., Reva, B., Koptyra, M., Chowdhury, S., Rykunov, D., Krek, A., Ma, W., Zhu, Y., Ji, J., et al. (2020) · Cell

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

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Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes

Victor, M. B., Richner, M., Olsen, H. E., Lee, S. W., Monteys, A. M., Ma, C., Huh, C. J., Zhang, B., Davidson, B. L., Yang, X. W., et al. (2018) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

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Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts

Huh, C. J., Zhang, B., Victor, M. B., Dahiya, S., Batista, L. F., Horvath, S., & Yoo, A. S. (2016) · eLife

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

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Evidence of CNIH3 involvement in opioid dependence

Nelson, E. C., Agrawal, A., Heath, A. C., Bogdan, R., Sherva, R., Zhang, B., Al-Hasani, R., Bruchas, M. R., Chou, Y.-L., Demers, C. H., et al. (2016) · Molecular Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

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Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy

Oh, Y. M., Lee, S. W., Kim, W. K., Chen, S., Church, V. A., Cates, K., Li, T., Zhang, B., Dolle, R. E., Dahiya, S., et al. (2022) · Nature Neuroscience

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

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Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs

Cates, K., McCoy, M. J., Kwon, J.-S., Liu, Y., Abernathy, D. G., Zhang, B., Liu, S., Gontarz, P., Kim, W. K., Chen, S., et al. (2021) · Cell Stem Cell

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

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Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis

Mallaney, C., Ostrander, E. L., Celik, H., Kramer, A. C., Martens, A., Kothari, A., Koh, W. K., Haussler, E., Iwamori, N., Gontarz, P., et al. (2019) · Leukemia

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

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Dnmt3a regulates T-cell development and suppresses T-ALL transformation

Kramer, A. C., Kothari, A., Wilson, W. C., Celik, H., Nikitas, J., Mallaney, C., Ostrander, E. L., Eultgen, E., Martens, A., Valentine, M. C., et al. (2017) · Leukemia

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

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