Hashimoto, Yuichi

Protein Knockdown Using Methyl Bestatin−Ligand Hybrid Molecules: Design and Synthesis of Inducers of Ubiquitination-Mediated Degradation of Cellular Retinoic Acid-Binding Proteins

Itoh, Y., Ishikawa, M., Naito, M., & Hashimoto, Y. (2010) · Journal of the American Chemical Society

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 404

Discovery of Small Molecules that Induce the Degradation of Huntingtin

Tomoshige, S., Nomura, S., Ohgane, K., Hashimoto, Y., & Ishikawa, M. (2017) · Angewandte Chemie International Edition

Genetic Neurodegenerative DiseasesProtein Degradation and Inhibitors

Cited by 144

Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein

Okuhira, K., Ohoka, N., Sai, K., Nishimaki-Mogami, T., Itoh, Y., Ishikawa, M., Hashimoto, Y., & Naito, M. (2011) · FEBS Letters

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 118

A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease‐relevant insults

Niikura, T., Hashimoto, Y., Tajima, H., Ishizaka, M., Yamagishi, Y., Kawasumi, M., Nawa, M., Terashita, K., Aiso, S., & Nishimoto, I. (2003) · European Journal of Neuroscience

Alzheimer's disease research and treatmentsUbiquitin and proteasome pathways

Cited by 115

An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling

Hashimoto, Y., Toyama, Y., Kusakari, S., Nawa, M., & Matsuoka, M. (2016) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsCell death mechanisms and regulation

Cited by 26

MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins

Tachi, N., Hashimoto, Y., & Matsuoka, M. (2012) · Biochemical Journal

Alzheimer's disease research and treatmentsCell death mechanisms and regulation

Cited by 20

Structural Identification of a Major Cytokinin in Coconut Milk as 14-O-{3-O-(.BETA.-D-Galactopyranosyl-(1.RAR.2)-.ALPHA.-D-galactopyranosyl-(1.RAR.3)-.ALPHA.-L-arabinofuranosyl)-4-O-(.ALPHA.-L-arabinofuranosyl)-.BETA.-D-galactopyranosyl}-trans-zeatin Riboside.

KOBAYASHI, H., MORISAKI, N., TAGO, Y., HASHIMOTO, Y., IWASAKI, S., KAWACHI, E., NAGATA, R., & SHUDO, K. (1997) · Chemical and Pharmaceutical Bulletin

Plant Molecular Biology ResearchCoconut Research and Applications

Cited by 18