Dai, Ning

mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry

Dai, N., Rapley, J., Angel, M., Yanik, M. F., Blower, M. D., & Avruch, J. (2011) · Genes & Development

PI3K/AKT/mTOR signaling in cancerRNA and protein synthesis mechanisms

Cited by 208

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

Dai, N., Zhao, L., Wrighting, D., Krämer, D., Majithia, A., Wang, Y., Cracan, V., Borges-Rivera, D., Mootha, V. K., Nahrendorf, M., et al. (2015) · Cell Metabolism

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 188

The Diverse Functions of IMP2/IGF2BP2 in Metabolism

Dai, N. (2020) · Trends in Endocrinology & Metabolism

RNA Research and SplicingPancreatic function and diabetes

Cited by 114

IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1

Dai, N., Ji, F., Wright, J., Minichiello, L., Sadreyev, R., & Avruch, J. (2017) · eLife

Growth Hormone and Insulin-like Growth FactorsRNA Research and Splicing

Cited by 103

The m 6 A reader IMP2 directs autoimmune inflammation through an IL-17– and TNFα-dependent C/EBP transcription factor axis

Bechara, R., Amatya, N., Bailey, R. D., Li, Y., Aggor, F. E. Y., Li, D.-D., Jawale, C. V., Coleman, B. M., Dai, N., Gokhale, N. S., et al. (2021) · Science Immunology

RNA modifications and cancerSystemic Lupus Erythematosus Research

Cited by 89

RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression

Regué, L., Zhao, L., Ji, F., Wang, H., Avruch, J., & Dai, N. (2021) · Molecular Metabolism

Pancreatic function and diabetesRNA modifications and cancer

Cited by 60