Schuppan, Detlef

The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Kazankov, K., Jørgensen, S. M. D., Thomsen, K. L., Møller, H. J., Vilstrup, H., George, J., Schuppan, D., & Grønbæk, H. (2019) · Nature Reviews Gastroenterology & Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 941

Hepatic fibrosis: concept to treatment

Trautwein, C., Friedman, S. L., Schuppan, D., & Pinzani, M. (2015) · Journal of Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 677

Chemical, pharmacological and clinical profile of the East Asian medical plant Centella aslatica

Brinkhaus, B., Lindner, M., Schuppan, D., & Hahn, E. G. (2000) · Phytomedicine

Medicinal Plants and NeuroprotectionPhytochemicals and Medicinal Plants

Cited by 525

Determinants of Fibrosis Progression and Regression in NASH

Schuppan, D., Surabattula, R., & Wang, X. Y. (2018) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 479

A Simple Validated Gluten-Free Diet Adherence Survey for Adults With Celiac Disease

Leffler, D. A., Dennis, M., Edwards George, J. B., Jamma, S., Magge, S., Cook, E. F., Schuppan, D., & Kelly, C. P. (2009) · Clinical Gastroenterology and Hepatology

Celiac Disease Research and ManagementNutritional Studies and Diet

Cited by 327

Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis

Farrell, G., Schattenberg, J. M., Leclercq, I., Yeh, M. M., Goldin, R., Teoh, N., & Schuppan, D. (2019) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 313

Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension

Helmstädter, J., Frenis, K., Filippou, K., Grill, A., Dib, M., Kalinovic, S., Pawelke, F., Kus, K., Kröller-Schön, S., Oelze, M., et al. (2020) · Arteriosclerosis, Thrombosis, and Vascular Biology

Diabetes Treatment and ManagementNitric Oxide and Endothelin Effects

Cited by 283

A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis

Harrison, S. A., Goodman, Z., Jabbar, A., Vemulapalli, R., Younes, Z. H., Freilich, B., Sheikh, M. Y., Schattenberg, J. M., Kayali, Z., Zivony, A., et al. (2020) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 260

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients

Teufel, A., Itzel, T., Erhart, W., Brosch, M., Wang, X. Y., Kim, Y. O., von Schönfels, W., Herrmann, A., Brückner, S., Stickel, F., et al. (2016) · Gastroenterology

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 229

Collagen biology and non‐invasive biomarkers of liver fibrosis

Karsdal, M. A., Daniels, S. J., Holm Nielsen, S., Bager, C., Rasmussen, D. G. K., Loomba, R., Surabattula, R., Villesen, I. F., Luo, Y., Shevell, D., et al. (2020) · Liver International

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 197

Clinical guide and update on porphyrias

Stölzel, U., Doss, M. O., & Schuppan, D. (2019) · Gastroenterology

Porphyrin Metabolism and DisordersNeonatal Health and Biochemistry

Cited by 175

Transglutaminases in inflammation and fibrosis of the gastrointestinal tract and the liver

Elli, L., Bergamini, C. M., Bardella, M. T., & Schuppan, D. (2009) · Digestive and Liver Disease

Celiac Disease Research and ManagementBlood properties and coagulation

Cited by 145

Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis

Yang, A.-T., Kim, Y.-O., Yan, X.-Z., Abe, H., Aslam, M., Park, K.-S., Zhao, X.-Y., Jia, J.-D., Klein, T., You, H., et al. (2023) · Cellular and Molecular Gastroenterology and Hepatology

Liver physiology and pathologyPeptidase Inhibition and Analysis

Cited by 144

Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins

Caminero, A., McCarville, J. L., Zevallos, V. F., Pigrau, M., Yu, X. B., Jury, J., Galipeau, H. J., Clarizio, A. V., Casqueiro, J., Murray, J. A., et al. (2019) · Gastroenterology

Celiac Disease Research and ManagementGut microbiota and health

Cited by 136

Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis

Popov, Y., Sverdlov, D. Y., Bhaskar, K. R., Sharma, A. K., Millonig, G., Patsenker, E., Krahenbuhl, S., Krahenbuhl, L., & Schuppan, D. (2010) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 136

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal

Weng, S.-Y., Wang, X., Vijayan, S., Tang, Y., Kim, Y. O., Padberg, K., Regen, T., Molokanova, O., Chen, T., Bopp, T., et al. (2018) · EBioMedicine

Liver physiology and pathologyCardiac Fibrosis and Remodeling

Cited by 128

Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids

Hellemans, K., Verbuyst, P., Quartier, E., Schuit, F., Rombouts, K., Chandraratna, R. A. S., Schuppan, D., & Geerts, A. (2004) · Hepatology

Liver physiology and pathologyRetinoids in leukemia and cellular processes

Cited by 102

Outcome measures in coeliac disease trials: the Tampere recommendations

Ludvigsson, J. F., Ciacci, C., Green, P. H., Kaukinen, K., Korponay-Szabo, I. R., Kurppa, K., Murray, J. A., Lundin, K. E. A., Maki, M. J., Popp, A., et al. (2018) · Gut

Celiac Disease Research and ManagementGastrointestinal motility and disorders

Cited by 100

Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer

Wei, G., An, P., Vaid, K. A., Nasser, I., Huang, P., Tan, L., Zhao, S., Schuppan, D., & Popov, Y. V. (2020) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 84

Gluten-Free Diet Reduces Symptoms, Particularly Diarrhea, in Patients With Irritable Bowel Syndrome and Antigliadin IgG

Pinto-Sanchez, M. I., Nardelli, A., Borojevic, R., De Palma, G., Calo, N. C., McCarville, J., Caminero, A., Basra, D., Mordhorst, A., Ignatova, E., et al. (2021) · Clinical Gastroenterology and Hepatology

Gastrointestinal motility and disordersCeliac Disease Research and Management

Cited by 57

Dual roles of B lymphocytes in mouse models of diet-induced nonalcoholic fatty liver disease

Karl, M., Hasselwander, S., Zhou, Y., Reifenberg, G., Kim, Y. O., Park, K., Ridder, D. A., Wang, X., Seidel, E., Hövelmeyer, N., et al. (2022) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 44

A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH

Fraser, D. A., Wang, X., Lund, J., Nikolić, N., Iruarrizaga-Lejarreta, M., Skjaeret, T., Alonso, C., Kastelein, J. J. P., Rustan, A. C., Kim, Y. O., et al. (2022) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentFatty Acid Research and Health

Cited by 41

NAFLD and NASH biomarker qualification in the LITMUS consortium – Lessons learned

Rasmussen, D. G. K., Anstee, Q. M., Torstenson, R., Golding, B., Patterson, S. D., Brass, C., Thakker, P., Harrison, S., Billin, A. N., Schuppan, D., et al. (2023) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentStatistical Methods in Clinical Trials

Cited by 41