Yamada, Yuichiro

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

Miyawaki, K., Yamada, Y., Ban, N., Ihara, Y., Tsukiyama, K., Zhou, H., Fujimoto, S., Oku, A., Tsuda, K., Toyokuni, S., et al. (2002) · Nature Medicine

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 963

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

Yasuda, K., Miyake, K., Horikawa, Y., Hara, K., Osawa, H., Furuta, H., Hirota, Y., Mori, H., Jonsson, A., Sato, Y., et al. (2008) · Nature Genetics

Genetic Associations and EpidemiologyPancreatic function and diabetes

Cited by 776

Over-expression of facilitative glucose transporter genes in human cancer

Yamamoto, T., Seino, Y., Fukumoto, H., Koh, G., Yano, H., Inagaki, N., Yamada, Y., Inoue, K., Manabe, T., & Imura, H. (1990) · Biochemical and Biophysical Research Communications

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 465

Glucose intolerance caused by a defect in the entero-insular axis: A study in gastric inhibitory polypeptide receptor knockout mice

Miyawaki, K., Yamada, Y., Yano, H., Niwa, H., Ban, N., Ihara, Y., Kubota, A., Fujimoto, S., Kajikawa, M., Kuroe, A., et al. (1999) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 454

The protective roles of GLP-1R signaling in diabetic nephropathy: possible mechanism and therapeutic potential

Fujita, H., Morii, T., Fujishima, H., Sato, T., Shimizu, T., Hosoba, M., Tsukiyama, K., Narita, T., Takahashi, T., Drucker, D. J., et al. (2014) · Kidney International

Chronic Kidney Disease and DiabetesDiabetes Treatment and Management

Cited by 336

The Murine Glucagon-Like Peptide-1 Receptor Is Essential for Control of Bone Resorption

Yamada, C., Yamada, Y., Tsukiyama, K., Yamada, K., Udagawa, N., Takahashi, N., Tanaka, K., Drucker, D. J., Seino, Y., & Inagaki, N. (2008) · Endocrinology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 318

Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, J. J., Schuit, F., & Drucker, D. J. (2004) · Diabetes

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 309

Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure

Hansotia, T., Maida, A., Flock, G., Yamada, Y., Tsukiyama, K., Seino, Y., & Drucker, D. J. (2007) · Journal of Clinical Investigation

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 290

GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose

Iwasaki, Y., Sendo, M., Dezaki, K., Hira, T., Sato, T., Nakata, M., Goswami, C., Aoki, R., Arai, T., Kumari, P., et al. (2018) · Nature Communications

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 200

Cdk5-dependent regulation of glucose-stimulated insulin secretion

Wei, F.-Y., Nagashima, K., Ohshima, T., Saheki, Y., Lu, Y.-F., Matsushita, M., Yamada, Y., Mikoshiba, K., Seino, Y., Matsui, H., et al. (2005) · Nature Medicine

Pancreatic function and diabetesIon channel regulation and function

Cited by 199

Gastric Inhibitory Polypeptide as an Endogenous Factor Promoting New Bone Formation after Food Ingestion

Tsukiyama, K., Yamada, Y., Yamada, C., Harada, N., Kawasaki, Y., Ogura, M., Bessho, K., Li, M., Amizuka, N., Sato, M., et al. (2006) · Molecular Endocrinology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 198

Safety and efficacy of once‐weekly semaglutide vs additional oral antidiabetic drugs in Japanese people with inadequately controlled type 2 diabetes: A randomized trial

Kaku, K., Yamada, Y., Watada, H., Abiko, A., Nishida, T., Zacho, J., & Kiyosue, A. (2018) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 132

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis

Pamir, N., Lynn, F. C., Buchan, A. M. J., Ehses, J., Hinke, S. A., Pospisilik, J. A., Miyawaki, K., Yamada, Y., Seino, Y., McIntosh, C. H. S., et al. (2003) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 126

Antioxidant α‐tocopherol ameliorates glycemic control of GK rats, a model of type 2 diabetes

Ihara, Y., Yamada, Y., Toyokuni, S., Miyawaki, K., Ban, N., Adachi, T., Kuroe, A., Iwakura, T., Kubota, A., Hiai, H., et al. (2000) · FEBS Letters

Antioxidant Activity and Oxidative StressNatural Antidiabetic Agents Studies

Cited by 124

Case of ketoacidosis by a sodium-glucose cotransporter 2 inhibitor in a diabetic patient with a low-carbohydrate diet

Hayami, T., Kato, Y., Kamiya, H., Kondo, M., Naito, E., Sugiura, Y., Kojima, C., Sato, S., Yamada, Y., Kasagi, R., et al. (2015) · Journal of Diabetes Investigation

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 115

Glucose-dependent insulinotropic polypeptide receptor therapies for the treatment of obesity, do agonists=antagonists?

Killion, E. A., Lu, S.-C., Fort, M., Yamada, Y., Véniant, M. M., & Lloyd, D. J. (2020) · Endocrine Reviews

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 94

Effects of thorough mastication on postprandial plasma glucose concentrations in nonobese Japanese subjects

Suzuki, H., Fukushima, M., Okamoto, S., Takahashi, O., Shimbo, T., Kurose, T., Yamada, Y., Inagaki, N., Seino, Y., & Fukui, T. (2005) · Metabolism

Food composition and propertiesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 84

Effects of GLP-1 receptor agonist on changes in the gut bacterium and the underlying mechanisms

Kato, S., Sato, T., Fujita, H., Kawatani, M., & Yamada, Y. (2021) · Scientific Reports

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 59

Glucagon-like peptide-1 (GLP-1) action in the mouse area postrema neurons

Kawatani, M., Yamada, Y., & Kawatani, M. (2018) · Peptides

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 32

GLP-1 Receptor Signaling Differentially Modifies the Outcomes of Sterile vs Viral Pulmonary Inflammation in Male Mice

Sato, T., Shimizu, T., Fujita, H., Imai, Y., Drucker, D. J., Seino, Y., & Yamada, Y. (2020) · Endocrinology

Diabetes Treatment and ManagementNeuropeptides and Animal Physiology

Cited by 29

Glucose-Dependent Insulinotropic Polypeptide Receptor Deficiency Leads to Impaired Bone Marrow Hematopoiesis

Mantelmacher, F. D., Fishman, S., Cohen, K., Pasmanik Chor, M., Yamada, Y., Zvibel, I., & Varol, C. (2017) · The Journal of Immunology

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 27

Efficacy and safety of oral semaglutide in Japanese patients with type 2 diabetes: A subgroup analysis by baseline variables in the PIONEER 9 and PIONEER 10 trials

Yabe, D., Deenadayalan, S., Horio, H., Kaneto, H., Jensen, T. B., Terauchi, Y., Yamada, Y., & Inagaki, N. (2022) · Journal of Diabetes Investigation

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 23

Efficacy and safety of oral semaglutide by baseline age in Japanese patients with type 2 diabetes: A subgroup analysis of the PIONEER 9 and 10 Japan trials

Yamada, Y., Yabe, D., Hertz, C. L., Horio, H., Nakamura, J., Nielsen, A. M., & Seino, Y. (2022) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 21

The Insulin Response to Oral Glucose in GIP and GLP-1 Receptor Knockout Mice: Review of the Literature and Stepwise Glucose Dose Response Studies in Female Mice

Ahrén, B., Yamada, Y., & Seino, Y. (2021) · Frontiers in Endocrinology

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 15