Li, Yonghe

Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer’s disease

Jia, L., Piña-Crespo, J., & Li, Y. (2019) · Molecular Brain

Alzheimer's disease research and treatmentsWnt/β-catenin signaling in development and cancer

Cited by 288

Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

Lu, W., Lin, C., Roberts, M. J., Waud, W. R., Piazza, G. A., & Li, Y. (2011) · PLoS ONE

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 230

Inhibition of Wnt/β-catenin pathway by niclosamide: A therapeutic target for ovarian cancer

Arend, R. C., Londoño-Joshi, A. I., Samant, R. S., Li, Y., Conner, M., Hidalgo, B., Alvarez, R. D., Landen, C. N., Straughn, J. M., & Buchsbaum, D. J. (2014) · Gynecologic Oncology

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

Cited by 161

LRP1 is a neuronal receptor for α-synuclein uptake and spread

Chen, K., Martens, Y. A., Meneses, A., Ryu, D. H., Lu, W., Raulin, A. C., Li, F., Zhao, J., Chen, Y., Jin, Y., et al. (2022) · Molecular Neurodegeneration

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 115

APOE3 -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia

Liu, C.-C., Murray, M. E., Li, X., Zhao, N., Wang, N., Heckman, M. G., Shue, F., Martens, Y., Li, Y., Raulin, A.-C., et al. (2021) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 108

Effect of Niclosamide on Basal-like Breast Cancers

Londoño-Joshi, A. I., Arend, R. C., Aristizabal, L., Lu, W., Samant, R. S., Metge, B. J., Hidalgo, B., Grizzle, W. E., Conner, M., Forero-Torres, A., et al. (2014) · Molecular Cancer Therapeutics

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

Cited by 97

ApoE4 reduction: An emerging and promising therapeutic strategy for Alzheimer's disease

Li, Y., Macyczko, J. R., Liu, C.-C., & Bu, G. (2022) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 61

Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding

Li, Y., Chen, J., Lu, W., McCormick, L. M., Wang, J., & Bu, G. (2005) · Journal of Cell Science

Wnt/β-catenin signaling in development and cancerCholesterol and Lipid Metabolism

Cited by 53

Sex specific molecular networks and key drivers of Alzheimer’s disease

Guo, L., Cao, J., Hou, J., Li, Y., Huang, M., Zhu, L., Zhang, L., Lee, Y., Duarte, M. L., Zhou, X., et al. (2023) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 49

APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

Zhao, J., Ikezu, T. C., Lu, W., Macyczko, J. R., Li, Y., Lewis-Tuffin, L. J., Martens, Y. A., Ren, Y., Zhu, Y., Asmann, Y. W., et al. (2023) · Stem Cell Research & Therapy

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 25

Modulation of LRP6‐mediated Wnt signaling by molecular chaperone Mesd

Li, Y., Lu, W., He, X., & Bu, G. (2006) · FEBS Letters

Wnt/β-catenin signaling in development and cancerHeat shock proteins research

Cited by 25

CI-994 is a dual modulator of class I HDACs and Wnt/β-catenin signaling for the treatment of Alzheimer's disease

Lu, W., Kawatani, K., Ren, Y., Nambara, T., Jia, L., Jeevaratnam, S., Lee, E., Martinez, P. R., Izhar, T., Wang, N., et al. (2026) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsHistone Deacetylase Inhibitors Research

Cited by 4