Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer’s disease

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Untitled work

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TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

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Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

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Canonical Wnt Signaling Regulates Organ-Specific Assembly and Differentiation of CNS Vasculature

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Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2

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Rapid Activity-Dependent Modifications in Synaptic Structure and Function Require Bidirectional Wnt Signaling

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Gpr124 Controls CNS Angiogenesis and Blood-Brain Barrier Integrity by Promoting Ligand-Specific Canonical Wnt Signaling

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The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway rescue in PC12 cells

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Canonical Wnt Signaling is Necessary for Object Recognition Memory Consolidation

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SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis

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Presenilin Deficiency or Lysosomal Inhibition Enhances Wnt Signaling through Relocalization of GSK3 to the Late-Endosomal Compartment

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Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

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Simvastatin Promotes Adult Hippocampal Neurogenesis by Enhancing Wnt/β-Catenin Signaling

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Chemical-Genetic Screen Identifies Riluzole as an Enhancer of Wnt/β-catenin Signaling in Melanoma

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Wnt pathway regulation by long-term moderate exercise in rat hippocampus

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Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer’s Disease

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Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism

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Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling

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Simvastatin Promotes Osteogenic Differentiation of Mouse Embryonic Stem Cells Via Canonical Wnt/β-Catenin Signaling

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Simvastatin Reverses High Glucose-Induced Apoptosis of Mesangial Cells via Modulation of Wnt Signaling Pathway

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High-Throughput Genetic Screen for Synaptogenic Factors: Identification of LRP6 as Critical for Excitatory Synapse Development

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Misregulation of Wnt Signaling Pathways at the Plasma Membrane in Brain and Metabolic Diseases

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Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response

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Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer’s Disease

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Mind Gaps and Bone Snaps: Exploring the Connection Between Alzheimer’s Disease and Osteoporosis

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Icariin ameliorates glycolytic dysfunction in Alzheimer's disease models by activating the Wnt/β‐catenin signaling pathway

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Resveratrol ameliorates learning and memory impairments induced by bilateral hippocampal injection of streptozotocin in mice

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Neurotrophic factor-secreting cells restored endogenous hippocampal neurogenesis through the Wnt/β-catenin signaling pathway in AD model mice

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Lipid Emulsion Improves Functional Recovery in an Animal Model of Stroke

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Neurovascular unit pathology is observed very early in disease progression in the mutant SOD1G93A mouse model of amyotrophic lateral sclerosis

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Notoginsenoside R2 reduces A β 25-35-induced neuronal apoptosis and inflammation via miR-27a/SOX8/ β -catenin axis

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Molecular explanation of Wnt/βcatenin antagonist pyrvinium mediated calcium equilibrium changes in aging cardiovascular disorders

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Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer’s disease at CPT1A locus

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Attenuative Effects of Fluoxetine and Triticum aestivum against Aluminum-Induced Alzheimer’s Disease in Rats: The Possible Consequences on Hepatotoxicity and Nephrotoxicity

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The efficacy and mechanism of berberine in improving aging-related cognitive dysfunction: A study based on network pharmacology

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Multiomic prediction of therapeutic targets for human diseases associated with protein phase separation

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Enhancing α-secretase Processing for Alzheimer’s Disease—A View on SFRP1

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Medicinal Herbs and Their Derived Ingredients Protect against Cognitive Decline in In Vivo Models of Alzheimer’s Disease

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Vitamin D and rosuvastatin alleviate type-II diabetes-induced cognitive dysfunction by modulating neuroinflammation and canonical/noncanonical Wnt/β-catenin signaling

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Identification of a novel pathway in sporadic Amyotrophic Lateral Sclerosis mediated by the long non-coding RNA ZEB1-AS1

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Infliximab and/or MESNA alleviate doxorubicin-induced Alzheimer's disease-like pathology in rats: A new insight into TNF-α/Wnt/β-catenin signaling pathway

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Boswellic acids ameliorate neurodegeneration induced by AlCl3: the implication of Wnt/β-catenin pathway

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FoxO1 and Wnt/β-catenin signaling pathway: Molecular targets of human amniotic mesenchymal stem cells-derived conditioned medium (hAMSC-CM) in protection against cerebral ischemia/reperfusion injury

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Crosstalk between Adult Hippocampal Neurogenesis and Its Role in Alzheimer’s Disease

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Therapeutic potential of targeting wingless-integrated/β-catenin/(Wnt/β-catenin) signaling pathway in Alzheimer's disease

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Targeting Wnt signaling in Alzheimer’s disease: mechanisms and therapeutic opportunities

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Role of Wnt/β-Catenin pathway in the Pathophysiology of Alzheimer’s Disease

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Molecular Insights to the Wnt Signaling During Alzheimer’s Disorder: a Potential Target for Therapeutic Interventions

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The association of the Wnt/β-catenin signaling pathway with Alzheimer's disease

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