Cai, Fang

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

Sun, X., He, G., Qing, H., Zhou, W., Dobie, F., Cai, F., Staufenbiel, M., Huang, L. E., & Song, W. (2006) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 605

Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes

Ly, P. T. T., Wu, Y., Zou, H., Wang, R., Zhou, W., Kinoshita, A., Zhang, M., Yang, Y., Cai, F., Woodgett, J., et al. (2013) · Journal of Clinical Investigation

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 442

Increased NF-Κb Signalling Up-Regulates BACE1 Expression and its Therapeutic Potential in Alzheimer's Disease

Chen, C.-H., Zhou, W., Liu, S., Deng, Y., Cai, F., Tone, M., Tone, Y., Tong, Y., & Song, W. (2012) · The International Journal of Neuropsychopharmacology

Alzheimer's disease research and treatmentsNF-κB Signaling Pathways

Cited by 433

Amyloid‐β protein (Aβ) Glu11 is the major β‐secretase site of β‐site amyloid‐β precursor protein‐cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis

Deng, Y., Wang, Z., Wang, R., Zhang, X., Zhang, S., Wu, Y., Staufenbiel, M., Cai, F., & Song, W. (2013) · European Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 108

Upregulation of MIF as a defense mechanism and a biomarker of Alzheimer’s disease

Zhang, S., Zhao, J., Zhang, Y., Zhang, Y., Cai, F., Wang, L., & Song, W. (2019) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 73

A presenilin-1 mutation causes Alzheimer disease without affecting Notch signaling

Zhang, S., Cai, F., Wu, Y., Bozorgmehr, T., Wang, Z., Zhang, S., Huang, D., Guo, J., Shen, L., Rankin, C., et al. (2020) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 66