Coleman, Michael P.

Axon degeneration mechanisms: Commonality amid diversity

Coleman, M. (2005) · Nature reviews. Neuroscience

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 819

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene

Mack, T. G. A., Reiner, M., Beirowski, B., Mi, W., Emanuelli, M., Wagner, D., Thomson, D., Gillingwater, T., Court, F., Conforti, L., et al. (2001) · Nature Neuroscience

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 611

Wallerian Degeneration, WldS, and Nmnat

Coleman, M. P., & Freeman, M. R. (2010) · Annual Review of Neuroscience

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 473

Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons

Gilley, J., & Coleman, M. P. (2010) · PLoS Biology

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 472

A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration ( Wld S ) mouse

Conforti, L., Tarlton, A., Mack, T. G. A., Mi, W., Buckmaster, E. A., Wagner, D., Perry, V. H., & Coleman, M. P. (2000) · Proceedings of the National Academy of Sciences

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 251

A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

Di Stefano, M., Nascimento-Ferreira, I., Orsomando, G., Mori, V, Gilley, J., Brown, R., Janeckova, L., Vargas, M. E., Worrell, L. A., Loreto, A., et al. (2015) · Cell Death & Differentiation

Nerve injury and regenerationSirtuins and Resveratrol in Medicine

Cited by 246

Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease

Ferri, A., Sanes, J. R., Coleman, M. P., Cunningham, J. M., & Kato, A. C. (2003) · Current Biology

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 221

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies

Adalbert, R., Nogradi, A., Babetto, E., Janeckova, L., Walker, S. A., Kerschensteiner, M., Misgeld, T., & Coleman, M. P. (2009) · Brain

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 177

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

Dembny, P., Newman, A. G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., et al. (2020) · JCI Insight

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 134

Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability

Gasparini, L., Anthony Crowther, R., Martin, K. R., Berg, N., Coleman, M., Goedert, M., & Spillantini, M. G. (2011) · Neurobiology of Aging

Alzheimer's disease research and treatmentsGlaucoma and retinal disorders

Cited by 133

Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration

Loreto, A., Hill, C. S., Hewitt, V. L., Orsomando, G., Angeletti, C., Gilley, J., Lucci, C., Sanchez-Martinez, A., Whitworth, A. J., Conforti, L., et al. (2020) · Neurobiology of Disease

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 131

Mechanisms of Axonal Spheroid Formation in Central Nervous System Wallerian Degeneration

Beirowski, B., Nógrádi, A., Babetto, E., Garcia-Alias, G., & Coleman, M. P. (2010) · Journal of Neuropathology & Experimental Neurology

Nerve injury and regenerationGlaucoma and retinal disorders

Cited by 104

Low levels of NMNAT2 compromise axon development and survival

Gilley, J., Mayer, P. R., Yu, G., & Coleman, M. P. (2019) · Human Molecular Genetics

Nerve injury and regenerationHereditary Neurological Disorders

Cited by 62

Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects

Groh, J., Abdelwahab, T., Kattimani, Y., Hörner, M., Loserth, S., Gudi, V., Adalbert, R., Imdahl, F., Saliba, A.-E., Coleman, M., et al. (2023) · Nature Communications

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 39

Axon Biology in ALS: Mechanisms of Axon Degeneration and Prospects for Therapy

Coleman, M. P. (2022) · Neurotherapeutics

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 33