Mali, Prashant

RNA-Guided Human Genome Engineering via Cas9

Mali, P., Yang, L., Esvelt, K. M., Aach, J., Guell, M., DiCarlo, J. E., Norville, J. E., & Church, G. M. (2013) · Science

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 9,210

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

Mali, P., Aach, J., Stranges, P. B., Esvelt, K. M., Moosburner, M., Kosuri, S., Yang, L., & Church, G. M. (2013) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,752

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

DiCarlo, J. E., Norville, J. E., Mali, P., Rios, X., Aach, J., & Church, G. M. (2013) · Nucleic Acids Research

CRISPR and Genetic EngineeringFungal and yeast genetics research

Cited by 1,566

Cas9 as a versatile tool for engineering biology

Mali, P., Esvelt, K. M., & Church, G. M. (2013) · Nature Methods

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,197

Highly Multiplexed Subcellular RNA Sequencing in Situ

Lee, J. H., Daugharthy, E. R., Scheiman, J., Kalhor, R., Yang, J. L., Ferrante, T. C., Terry, R., Jeanty, S. S. F., Li, C., Amamoto, R., et al. (2014) · Science

Single-cell and spatial transcriptomicsRNA Research and Splicing

Cited by 973

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

Esvelt, K. M., Mali, P., Braff, J. L., Moosburner, M., Yaung, S. J., & Church, G. M. (2013) · Nature Methods

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 786

A Multifunctional AAV-CRISPR-Cas9 and Its Host Response

Chew, W. L., Tabebordbar, M., Cheng, J. K. W., Mali, P., Wu, E. Y., Ng, A. H. M., Zhu, K., Wagers, A. J., & Church, G. M. (2016) · Nature Methods

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 617

Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.

Mali, P., Chou, B.-K., Yen, J., Ye, Z., Zou, J., Dowey, S., Brodsky, R. A., Ohm, J. E., Yu, W., Baylin, S. B., et al. (2010) · Stem Cells

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 417

Developmental barcoding of whole mouse via homing CRISPR

Kalhor, R., Kalhor, K., Mejia, L., Leeper, K., Graveline, A., Mali, P., & Church, G. M. (2018) · Science

CRISPR and Genetic EngineeringDevelopmental Biology and Gene Regulation

Cited by 363

Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions

Shen, J. P., Zhao, D., Sasik, R., Luebeck, J., Birmingham, A., Bojorquez-Gomez, A., Licon, K., Klepper, K., Pekin, D., Beckett, A. N., et al. (2017) · Nature Methods

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 359

Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts

Mali, P., Ye, Z., Hommond, H. H., Yu, X., Lin, J., Chen, G., Zou, J., & Cheng, L. (2008) · Stem Cells

Pluripotent Stem Cells ResearchMesenchymal stem cell research

Cited by 291

RNA editing: Expanding the potential of RNA therapeutics

Booth, B. J., Nourreddine, S., Katrekar, D., Savva, Y., Bose, D., Long, T. J., Huss, D. J., & Mali, P. (2023) · Molecular Therapy

RNA regulation and diseaseRNA modifications and cancer

Cited by 171

In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation

Moreno, A. M., Fu, X., Zhu, J., Katrekar, D., Shih, Y.-R. V., Marlett, J., Cabotaje, J., Tat, J., Naughton, J., Lisowski, L., et al. (2018) · Molecular Therapy

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 159

Oligonucleotide conjugated multi-functional adeno-associated viruses

Katrekar, D., Moreno, A. M., Chen, G., Worlikar, A., & Mali, P. (2018) · Scientific Reports

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 57