Novotny, Mark

Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons

Krishnaswami, S. R., Grindberg, R. V., Novotny, M., Venepally, P., Lacar, B., Bhutani, K., Linker, S. B., Pham, S., Erwin, J. A., Miller, J. A., et al. (2016) · Nature Protocols

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 445

RNA-sequencing from single nuclei

Grindberg, R. V., Yee-Greenbaum, J. L., McConnell, M. J., Novotny, M., O’Shaughnessy, A. L., Lambert, G. M., Araúzo-Bravo, M. J., Lee, J., Fishman, M., Robbins, G. E., et al. (2013) · Proceedings of the National Academy of Sciences

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 422

Nuclear RNA-seq of single neurons reveals molecular signatures of activation

Lacar, B., Linker, S. B., Jaeger, B. N., Krishnaswami, S. R., Barron, J. J., Kelder, M. J. E., Parylak, S. L., Paquola, A. C. M., Venepally, P., Novotny, M., et al. (2016) · Nature Communications

Single-cell and spatial transcriptomicsMemory and Neural Mechanisms

Cited by 405

Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

Boldog, E., Bakken, T. E., Hodge, R. D., Novotny, M., Aevermann, B. D., Baka, J., Bordé, S., Close, J. L., Diez-Fuertes, F., Ding, S.-L., et al. (2018) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchSingle-cell and spatial transcriptomics

Cited by 291

L1-associated genomic regions are deleted in somatic cells of the healthy human brain

Erwin, J. A., Paquola, A. C. M., Singer, T., Gallina, I., Novotny, M., Quayle, C., Bedrosian, T. A., Alves, F. I. A., Butcher, C. R., Herdy, J. R., et al. (2016) · Nature Neuroscience

Genomic variations and chromosomal abnormalitiesChromosomal and Genetic Variations

Cited by 195

Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis

Kang, J., Lienhard, M., Pastor, W. A., Chawla, A., Novotny, M., Tsagaratou, A., Lasken, R. S., Thompson, E. C., Surani, M. A., Koralov, S. B., et al. (2015) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 126

Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells

Brown, D. M., Hixon, A. M., Oldfield, L. M., Zhang, Y., Novotny, M., Wang, W., Das, S. R., Shabman, R. S., Tyler, K. L., & Scheuermann, R. H. (2018) · mBio

Viral Infections and Immunology ResearchInfectious Encephalopathies and Encephalitis

Cited by 105

Cell type discovery and representation in the era of high-content single cell phenotyping

Bakken, T., Cowell, L., Aevermann, B. D., Novotny, M., Hodge, R., Miller, J. A., Lee, A., Chang, I., McCorrison, J., Pulendran, B., et al. (2017) · BMC Bioinformatics

Single-cell and spatial transcriptomicsBiomedical Text Mining and Ontologies

Cited by 55