Ota, Tsuguhito

A liver-derived secretory protein, selenoprotein P, causes insulin resistance

Misu, H., Takamura, T., Takayama, H., Hayashi, H., Matsuzawa-Nagata, N., Kurita, S., Ishikura, K., Ando, H., Takeshita, Y., Ota, T., et al. (2010) · Cell Metabolism

Adipokines, Inflammation, and Metabolic DiseasesSelenium in Biological Systems

Cited by 583

Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria.

Nakamura, S., Takamura, T., Matsuzawa-Nagata, N., Takayama, H., Misu, H., Noda, H., Nabemoto, S., Kurita, S., Ota, T., Ando, H., et al. (2009) · Journal of Biological Chemistry

Liver Disease Diagnosis and TreatmentMetabolism, Diabetes, and Cancer

Cited by 426

LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance

Lan, F., Misu, H., Chikamoto, K., Takayama, H., Kikuchi, A., Mohri, K., Takata, N., Hayashi, H., Matsuzawa-Nagata, N., Takeshita, Y., et al. (2014) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesLiver Disease Diagnosis and Treatment

Cited by 158

Emerging roles of SGLT2 inhibitors in obesity and insulin resistance: Focus on fat browning and macrophage polarization

Xu, L., & Ota, T. (2017) · Adipocyte

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 134

Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes

Misu, H., Ishikura, K., Kurita, S., Takeshita, Y., Ota, T., Saito, Y., Takahashi, K., Kaneko, S., & Takamura, T. (2012) · PLoS ONE

Adipokines, Inflammation, and Metabolic DiseasesSelenium in Biological Systems

Cited by 105

Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes

Misu, H., Takamura, T., Matsuzawa, N., Shimizu, A., Ota, T., Sakurai, M., Ando, H., Arai, K., Yamashita, T., Honda, M., et al. (2007) · Diabetologia

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 102

Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients

Takamura, T., Misu, H., Matsuzawa‐Nagata, N., Sakurai, M., Ota, T., Shimizu, A., Kurita, S., Takeshita, Y., Ando, H., Honda, M., et al. (2008) · Obesity

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 96

CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status

Ni, Y., Zhuge, F., Ni, L., Nagata, N., Yamashita, T., Mukaida, N., Kaneko, S., Ota, T., & Nagashimada, M. (2022) · Metabolism

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 86

Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor

Kimura, K., Tanida, M., Nagata, N., Inaba, Y., Watanabe, H., Nagashimada, M., Ota, T., Asahara, S.-I., Kido, Y., Matsumoto, M., et al. (2016) · Cell Reports

Vagus Nerve Stimulation ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 84

Prevention of NAFLD/NASH by Astaxanthin and β-Cryptoxanthin

Ota, T. (2021) · Advances in Experimental Medicine and Biology

Liver Disease Diagnosis and TreatmentAntioxidant Activity and Oxidative Stress

Cited by 10