Inoue, Haruhisa

Induced pluripotent stem cell technology: a decade of progress.

Shi, Y., Inoue, H., Wu, J. C., & Yamanaka, S. (2017) · Nature Reviews Drug Discovery

Pluripotent Stem Cells ResearchMesenchymal stem cell research

Cited by 1,525

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of parkin

Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y., & Takahashi, R. (2001) · Cell

Parkinson's Disease Mechanisms and TreatmentsEndoplasmic Reticulum Stress and Disease

Cited by 1,050

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

Kondo, T., Asai, M., Tsukita, K., Kutoku, Y., Ohsawa, Y., Sunada, Y., Imamura, K., Egawa, N., Yahata, N., Okita, K., et al. (2013) · Cell Stem Cell

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 741

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model

Kikuchi, T., Morizane, A., Doi, D., Magotani, H., Onoe, H., Hayashi, T., Mizuma, H., Takara, S., Takahashi, R., Inoue, H., et al. (2017) · Nature

Pluripotent Stem Cells ResearchParkinson's Disease Mechanisms and Treatments

Cited by 702

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

Chui, D.-H., Tanahashi, H., Ozawa, K., Ikeda, S., Checler, F., Ueda, O., Suzuki, H., Araki, W., Inoue, H., Shirotani, K., et al. (1999) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 364

P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating

Takeuchi, H., Iba, M., Inoue, H., Higuchi, M., Takao, K., Tsukita, K., Karatsu, Y., Iwamoto, Y., Miyakawa, T., Suhara, T., et al. (2011) · PLoS ONE

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 247

iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer’s Disease

Kondo, T., Imamura, K., Funayama, M., Tsukita, K., Miyake, M., Ohta, A., Woltjen, K., Nakagawa, M., Asada, T., Arai, T., et al. (2017) · Cell Reports

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 221

Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis.

Tashiro, Y., Urushitani, M., Inoue, H., Koike, M., Uchiyama, Y., Komatsu, M., Tanaka, K., Yamazaki, M., Abe, M., Misawa, H., et al. (2012) · Journal of Biological Chemistry

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 194

Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs

Yoshida, M., Kitaoka, S., Egawa, N., Yamane, M., Ikeda, R., Tsukita, K., Amano, N., Watanabe, A., Morimoto, M., Takahashi, J., et al. (2015) · Stem Cell Reports

Neurogenetic and Muscular Disorders ResearchPluripotent Stem Cells Research

Cited by 102

N-cadherin Regulates p38 MAPK Signaling via Association with JNK-associated Leucine Zipper Protein

Ando, K., Uemura, K., Kuzuya, A., Maesako, M., Asada-Utsugi, M., Kubota, M., Aoyagi, N., Yoshioka, K., Okawa, K., Inoue, H., et al. (2011) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 66

microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity

Horie, T., Nakao, T., Miyasaka, Y., Nishino, T., Matsumura, S., Nakazeki, F., Ide, Y., Kimura, M., Tsuji, S., Rodriguez, R. R., et al. (2021) · Nature Communications

Adipose Tissue and MetabolismMicroRNA in disease regulation

Cited by 49

Chemical genomics language model toward reliable and explainable compound-protein interaction exploration

Koyama, T., Tsumura, H., Okita, R., Yamazaki, K., Hasegawa, A., Imamura, K., Kato, T., Iwata, H., Kojima, R., Inoue, H., et al. (2026) · Journal of Cheminformatics

Computational Drug Discovery MethodsMachine Learning in Bioinformatics

Cited by 9