Winkler, James D.
Arvinas (United States)
6 papers on CoChat
Most cited papers
- Verified
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4
Lu, J., Qian, Y., Altieri, M., Dong, H., Wang, J., Raina, K., Hines, J., Winkler, J. D., Crew, A. P., Coleman, K., et al. (2015) · Chemistry & Biology
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 1,140
- Verified
PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer
Raina, K., Lu, J., Qian, Y., Altieri, M., Gordon, D., Rossi, A. M. K., Wang, J., Chen, X., Dong, H., Siu, K., et al. (2016) · Proceedings of the National Academy of Sciences
Protein Degradation and InhibitorsProstate Cancer Treatment and Research
Cited by 852
- Verified
Targeted protein degradation by PROTACs
Neklesa, T. K., Winkler, J. D., & Crews, C. M. (2017) · Pharmacology & Therapeutics
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 599
- Verified
Cloning and Characterization of a Novel Human Class I Histone Deacetylase That Functions as a Transcription Repressor
Hu, E., Chen, Z., Fredrickson, T., Zhu, Y., Kirkpatrick, R., Zhang, G.-F., Johanson, K., Sung, C.-M., Liu, R., & Winkler, J. (2000) · Journal of Biological Chemistry
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 309
- Verified
Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1
Crew, A. P., Raina, K., Dong, H., Qian, Y., Wang, J., Vigil, D., Serebrenik, Y. V., Hamman, B. D., Morgan, A., Ferraro, C., et al. (2018) · Journal of Medicinal Chemistry
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 257
- Verified
Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) α and β messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells
Chen, Z., Clark, S., Birkeland, M., Sung, C.-M., Lago, A., Liu, R., Kirkpatrick, R., Johanson, K., Winkler, J. D., & Hu, E. (2002) · Cancer Letters
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 87
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