Mitchell, James B.

Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

Wink, D. A., & Mitchell, J. B. (1998) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 1,606

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues

Chen, Q., Espey, M. G., Krishna, M. C., Mitchell, J. B., Corpe, C. P., Buettner, G. R., Shacter, E., & Levine, M. (2005) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchCancer and biochemical research

Cited by 1,075

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

Li, F., Jiang, C., Krausz, K. W., Li, Y., Albert, I., Hao, H., Fabre, K. M., Mitchell, J. B., Patterson, A. D., & Gonzalez, F. J. (2013) · Nature Communications

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 705

Radioprotectors and mitigators of radiation-induced normal tissue injury

Citrin, D., Cotrim, A. P., Hyodo, F., Baum, B. J., Krishna, M. C., & Mitchell, J. B. (2010) · The Oncologist

Effects of Radiation ExposureRadiation Therapy and Dosimetry

Cited by 482

mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis

Iglesias-Bartolome, R., Patel, V., Cotrim, A., Leelahavanichkul, K., Molinolo, A. A., Mitchell, J. B., & Gutkind, J. S. (2012) · Cell Stem Cell

Oral health in cancer treatmentTelomeres, Telomerase, and Senescence

Cited by 284

Interference with Transforming Growth Factor-β/ Smad3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin

Flanders, K. C., Major, C. D., Arabshahi, A., Aburime, E. E., Okada, M. H., Fujii, M., Blalock, T. D., Schultz, G. S., Sowers, A., Anzano, M. A., et al. (2003) · The American Journal of Pathology

Wound Healing and TreatmentsTGF-β signaling in diseases

Cited by 167

PX‐478, an inhibitor of hypoxia‐inducible factor‐1α, enhances radiosensitivity of prostate carcinoma cells

Palayoor, S. T., Mitchell, J. B., Cerna, D., DeGraff, W., John‐Aryankalayil, M., & Coleman, C. N. (2008) · International Journal of Cancer

Cancer, Hypoxia, and MetabolismRadiation Therapy and Dosimetry

Cited by 132

Superoxide fluxes limit nitric oxide-induced signaling

Thomas, D. D., Ridnour, L. A., Espey, M. G., Donzelli, S., Ambs, S., Hussain, S. P., Harris, C. C., DeGraff, W., Roberts, D. D., Mitchell, J. B., et al. (2006) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 121

The catecholic metal sequestering agent 1,2-dihydroxybenzene-3,5-disulfonate confers protection against oxidative cell damage

Krishna, C. M., Liebmann, J. E., Kaufman, D., DeGraff, W., Hahn, S. M., McMurry, T., Mitchell, J. B., & Russo, A. (1992) · Archives of Biochemistry and Biophysics

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 110

Neuroprotection by the stable nitroxide tempol during reperfusion in a rat model of transient focal ischemia

Rak, R., Chao, D. L., Pluta, R. M., Mitchell, J. B., Oldfield, E. H., & Watson, J. C. (2000) · Journal of Neurosurgery

Neuroprotection in Cerebral IschemiaAcute Ischemic Stroke Management

Cited by 106

Absolute oxygen tension (pO2) in murine fatty and muscle tissue as determined by EPR

Matsumoto, A., Matsumoto, S., Sowers, A. L., Koscielniak, J. W., Trigg, N. J., Kuppusamy, P., Mitchell, J. B., Subramanian, S., Krishna, M. C., & Matsumoto, K. (2005) · Magnetic Resonance in Medicine

Electron Spin Resonance StudiesAdvanced MRI Techniques and Applications

Cited by 92

Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice

Kishimoto, S., Brender, J. R., Crooks, D. R., Matsumoto, S., Seki, T., Oshima, N., Merkle, H., Lin, P., Reed, G., Chen, A. P., et al. (2019) · eLife

Advanced NMR Techniques and ApplicationsCancer, Hypoxia, and Metabolism

Cited by 41

Molecular imaging of the tumor microenvironment reveals the relationship between tumor oxygenation, glucose uptake, and glycolysis in pancreatic ductal adenocarcinoma

Yamamoto, K., Brender, J. R., Seki, T., Kishimoto, S., Oshima, N., Choudhuri, R., Adler, S. S., Jagoda, E. M., Saito, K., Devasahayam, N., et al. (2020) · Cancer Research

Cancer, Hypoxia, and MetabolismMedical Imaging Techniques and Applications

Cited by 37

Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and no donors: insights into listeriocidal activity of oxidative and nitrosative stress

Ogawa, R., Pacelli, R., Espey, M. G., Miranda, K. M., Friedman, N., Kim, S., Cox, G., Mitchell, J. B., Wink, D. A., & Russo, A. (2001) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 35

Stable Isotope- and Mass Spectrometry-based Metabolomics as Tools in Drug Metabolism: A Study Expanding Tempol Pharmacology

Li, F., Pang, X., Krausz, K. W., Jiang, C., Chen, C., Cook, J. A., Krishna, M. C., Mitchell, J. B., Gonzalez, F. J., & Patterson, A. D. (2013) · Journal of Proteome Research

Metabolomics and Mass Spectrometry StudiesPharmacogenetics and Drug Metabolism

Cited by 31

Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches—Meeting Viewpoint

Ahmed, M. M., Coleman, C. N., Mendonca, M., Bentzen, S., Vikram, B., Seltzer, S. M., Goodhead, D., Obcemea, C., Mohan, R., Prise, K. M., et al. (2018) · Cancer Research

Radiation Therapy and DosimetryAdvanced Radiotherapy Techniques

Cited by 27