Danos, Olivier

Nucleotide sequence of the AIDS virus, LAV

Wain-Hobson, S., Sonigo, P., Danos, O., Cole, S., & Alizon, M. (1985) · Cell

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 1,202

Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation

Douar, A.-M., Poulard, K., Stockholm, D., & Danos, O. (2001) · Journal of Virology

Virus-based gene therapy researchCellular transport and secretion

Cited by 282

Intracerebral Administration of Adeno-Associated Viral Vector Serotype rh.10 Carrying Human SGSH and SUMF1 cDNAs in Children with Mucopolysaccharidosis Type IIIA Disease: Results of a Phase I/II Trial

Tardieu, M., Zérah, M., Husson, B., de Bournonville, S., Deiva, K., Adamsbaum, C., Vincent, F., Hocquemiller, M., Broissand, C., Furlan, V., et al. (2014) · Human Gene Therapy

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 261

Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice

Rivière, C., Danos, O., & Douar, A. M. (2006) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 192

FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia

Raslova, H., Komura, E., Le Couédic, J. P., Larbret, F., Debili, N., Feunteun, J., Danos, O., Albagli, O., Vainchenker, W., & Favier, R. (2004) · Journal of Clinical Investigation

Platelet Disorders and TreatmentsAcute Myeloid Leukemia Research

Cited by 174

Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34 + Hematopoietic Stem and Progenitor Cells

Chang, K.-H., Smith, S. E., Sullivan, T., Chen, K., Zhou, Q., West, J. A., Liu, M., Liu, Y., Vieira, B. F., Sun, C., et al. (2017) · Molecular Therapy - Methods & Clinical Development

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 155

AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expression

Ding, K., Shen, J., Hafiz, Z., Hackett, S. F., Silva, R. L. E., Khan, M., Lorenc, V. E., Chen, D., Chadha, R., Zhang, M., et al. (2019) · Journal of Clinical Investigation

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 141

Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts.

Cartier, N., Lopez, J., Moullier, P., Rocchiccioli, F., Rolland, M. O., Jorge, P., Mosser, J., Mandel, J. L., Bougnères, P. F., & Danos, O. (1995) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchMetabolism and Genetic Disorders

Cited by 105

Characterization of AAV-mediated dorsal root ganglionopathy

Buss, N., Lanigan, L., Zeller, J., Cissell, D., Metea, M., Adams, E., Higgins, M., Kim, K. H., Budzynski, E., Yang, L., et al. (2022) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchPain Mechanisms and Treatments

Cited by 81

Transient Immunomodulation Allows Repeated Injections of AAV1 and Correction of Muscular Dystrophy in Multiple Muscles

Lorain, S., Gross, D.-A., Goyenvalle, A., Danos, O., Davoust, J., & Garcia, L. (2008) · Molecular Therapy

Virus-based gene therapy researchNeurogenetic and Muscular Disorders Research

Cited by 62

HLA-A*0201-restricted cytolytic responses to the rtTA transactivator dominant and cryptic epitopes compromise transgene expression induced by the tetracycline on system

Ginhoux, F., Turbant, S., Gross, D. A., Poupiot, J., Marais, T., Lone, Y., Lemonnier, F. A., Firat, H., Perez, N., Danos, O., et al. (2004) · Molecular Therapy

Immunotherapy and Immune Responsesvaccines and immunoinformatics approaches

Cited by 49

Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors

Hollidge, B. S., Carroll, H. B., Qian, R., Fuller, M. L., Giles, A. R., Mercer, A. C., Danos, O., Liu, Y., Bruder, J. T., & Smith, J. B. (2022) · Frontiers in Neurology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 45

CD4+ CD25+ regulatory T cells inhibit immune-mediated transgene rejection

Gross, D.-A., Leboeuf, M., Gjata, B., Danos, O., & Davoust, J. (2003) · Blood

Virus-based gene therapy researchT-cell and B-cell Immunology

Cited by 45

Sex Difference Leads to Differential Gene Expression Patterns and Therapeutic Efficacy in Mucopolysaccharidosis IVA Murine Model Receiving AAV8 Gene Therapy

Piechnik, M., Amendum, P. C., Sawamoto, K., Stapleton, M., Khan, S., Fnu, N., Álvarez, V., Pachon, A. M. H., Danos, O., Bruder, J. T., et al. (2022) · International Journal of Molecular Sciences

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 28

Deleterious effect of peptide insertions in a permissive site of the AAV2 capsid

Douar, A. M., Poulard, K., & Danos, O. (2003) · Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 17

The Cellular Processing Capacity Limits the Amounts of Chimeric U7 snRNA Available for Antisense Delivery

Eckenfelder, A., Tordo, J., Babbs, A., Davies, K. E., Goyenvalle, A., & Danos, O. (2012) · Molecular Therapy - Nucleic Acids

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 17

RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction

Julien, L., Chassagne, J., Peccate, C., Lorain, S., Piétri-Rouxel, F., Danos, O., & Benkhelifa-Ziyyat, S. (2018) · Scientific Reports

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 13

The presence of CpGs in AAV gene therapy vectors induces a plasmacytoid dendritic cell-like population very early after administration

Glenn, J. D., Negash, H., Henry, W., Qian, R., Liu, Y., Danos, O., Bruder, J. T., & Karumuthil-Melethil, S. (2024) · Cellular Immunology

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 6