Fersht, Alan R.

Awakening guardian angels: drugging the p53 pathway

Brown, C. J., Lain, S., Verma, C. S., Fersht, A. R., & Lane, D. P. (2009) · Nature Reviews Cancer

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 881

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

Lambert, J. M. R., Gorzov, P., Veprintsev, D. B., Söderqvist, M., Segerbäck, D., Bergman, J., Fersht, A. R., Hainaut, P., Wiman, K. G., & Bykov, V. J. N. (2009) · Cancer Cell

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 592

Nucleation mechanisms in protein folding

Fersht, A. R. (1997) · Current Opinion in Structural Biology

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 545

Core domain interactions in full-length p53 in solution

Veprintsev, D. B., Freund, S. M. V., Andreeva, A., Rutledge, S. E., Tidow, H., Cañadillas, J. M. P., Blair, C. M., & Fersht, A. R. (2006) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsCancer-related Molecular Pathways

Cited by 95