Kahn, C. Ronald

Insulin signalling and the regulation of glucose and lipid metabolism

Saltiel, A. R., & Kahn, C. R. (2001) · Nature

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 5,326

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

Sun, X. J., Rothenberg, P., Kahn, C. R., Backer, J. M., Araki, E., Wilden, P. A., Cahill, D. A., Goldstein, B. J., & White, M. F. (1991) · Nature

Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling

Cited by 1,574

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

Cusi, K., Maezono, K., Osman, A., Pendergrass, M., Patti, M. E., Pratipanawatr, T., DeFronzo, R. A., Kahn, C. R., & Mandarino, L. J. (2000) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,139

Insulin Action, Diabetogenes, and the Cause of Type II Diabetes

Kahn, C. R. (1994) · Diabetes

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 916

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

Softic, S., Cohen, D. E., & Kahn, C. R. (2016) · Digestive Diseases and Sciences

Diet, Metabolism, and DiseaseLiver Disease Diagnosis and Treatment

Cited by 709

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

Wang, J., Wilhelmsson, H., Graff, C., Li, H., Oldfors, A., Rustin, P., Brüning, J. C., Kahn, C. R., Clayton, D. A., Barsh, G. S., et al. (1999) · Nature Genetics

Mitochondrial Function and PathologyCardiac electrophysiology and arrhythmias

Cited by 435

Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats.

Saad, M. J., Folli, F., Kahn, J. A., & Kahn, C. R. (1993) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 349

Expression and function of IRS-1 in insulin signal transmission.

Sun, X. J., Miralpeix, M., Myers, M. G., Glasheen, E. M., Backer, J. M., Kahn, C. R., & White, M. F. (1992) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling

Cited by 326

Decreased Muscle Glucose-Transport Phosphorylation Is an Early Defect in the Pathogenesis of Non-Insulin-Dependent Diabetes-Mellitus

Rothman, D. L., Magnusson, I., Cline, G., Gerard, D., Kahn, C. R., Shulman, R. G., & Shulman, G. I. (1995) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 325

Selective Insulin Signaling through A and B Insulin Receptors Regulates Transcription of Insulin and Glucokinase Genes in Pancreatic β Cells

Leibiger, B., Leibiger, I. B., Moede, T., Kemper, S., Kulkarni, R. N., Kahn, C. R., de Vargas, L. M., & Berggren, P.-O. (2001) · Molecular Cell

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 267

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance

Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., et al. (2012) · Cell Metabolism

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 245

Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

Kim, J. K., Zisman, A., Fillmore, J. J., Peroni, O. D., Kotani, K., Perret, P., Zong, H., Dong, J., Kahn, C. R., Kahn, B. B., et al. (2001) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 202

Essential Role of Insulin Receptor Substrate-2 in Insulin Stimulation of Glut4 Translocation and Glucose Uptake in Brown Adipocytes

Fasshauer, M., Klein, J., Ueki, K., Kriauciunas, K. M., Benito, M., White, M. F., & Kahn, C. R. (2000) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 176

Essential Role of Insulin and Insulin-Like Growth Factor 1 Receptor Signaling in Cardiac Development and Function

Laustsen, P. G., Russell, S. J., Cui, L., Entingh-Pearsall, A., Holzenberger, M., Liao, R., & Kahn, C. R. (2007) · Molecular and Cellular Biology

Growth Hormone and Insulin-like Growth FactorsCardiovascular Function and Risk Factors

Cited by 173

Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice

Yechoor, V. K., Patti, M.-E., Saccone, R., & Kahn, C. R. (2002) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 156

ATP induces a conformational change of the 90-kDa heat shock protein (hsp90).

Csermely, P., Kajtár, J., Hollósi, M., Jalsovszky, G., Holly, S., Kahn, C. R., Gergely, P., Söti, C., Mihály, K., & Somogyi, J. (1993) · Journal of Biological Chemistry

Heat shock proteins researchProtein Structure and Dynamics

Cited by 133

Absence of Insulin Receptor Substrate-1 Expression Does Not Alter GLUT1 or GLUT4 Abundance or Contraction-Stimulated Glucose Uptake by Mouse Skeletal Muscle

Dumke, C. L., Wetter, A. C., Arias, E. B., Kahn, C. R., & Cartee, G. D. (2001) · Hormone and Metabolic Research

Metabolism, Diabetes, and CancerMuscle Physiology and Disorders

Cited by 7