Takayanagi, Hiroshi

Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

Takayanagi, H. (2007) · Nature Reviews Immunology

Bone Metabolism and DiseasesOsteomyelitis and Bone Disorders Research

Cited by 1,878

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

Sato, K., Suematsu, A., Okamoto, K., Yamaguchi, A., Morishita, Y., Kadono, Y., Tanaka, S., Kodama, T., Akira, S., Iwakura, Y., et al. (2006) · The Journal of Experimental Medicine

Bone Metabolism and DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 1,554

The molecular understanding of osteoclast differentiation

Asagiri, M., & Takayanagi, H. (2007) · Bone

Bone Metabolism and DiseasesSignaling Pathways in Disease

Cited by 1,363

Estrogen Prevents Bone Loss via Estrogen Receptor α and Induction of Fas Ligand in Osteoclasts

Nakamura, T., Imai, Y., Matsumoto, T., Sato, S., Takeuchi, K., Igarashi, K., Harada, Y., Azuma, Y., Krust, A., Yamamoto, Y., et al. (2007) · Cell

Bone Metabolism and DiseasesEstrogen and related hormone effects

Cited by 1,013

Autoamplification of NFATc1 expression determines its essential role in bone homeostasis

Asagiri, M., Sato, K., Usami, T., Ochi, S., Nishina, H., Yoshida, H., Morita, I., Wagner, E. F., Mak, T. W., Serfling, E., et al. (2005) · The Journal of Experimental Medicine

Bone Metabolism and DiseasesSignaling Pathways in Disease

Cited by 849

Suppression of bone formation by osteoclastic expression of semaphorin 4D

Negishi-Koga, T., Shinohara, M., Komatsu, N., Bito, H., Kodama, T., Friedel, R. H., & Takayanagi, H. (2011) · Nature Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 498

Essential Role of p38 Mitogen-activated Protein Kinase in Cathepsin K Gene Expression during Osteoclastogenesis through Association of NFATc1 and PU.1

Matsumoto, M., Kogawa, M., Wada, S., Takayanagi, H., Tsujimoto, M., Katayama, S., Hisatake, K., & Nogi, Y. (2004) · Journal of Biological Chemistry

Bone Metabolism and DiseasesSignaling Pathways in Disease

Cited by 436

Ca 2+ ‐NFATc1 signaling is an essential axis of osteoclast differentiation

Negishi‐Koga, T., & Takayanagi, H. (2009) · Immunological Reviews

Bone Metabolism and DiseasesSignaling Pathways in Disease

Cited by 415

Mechanistic insight into osteoclast differentiation in osteoimmunology

Takayanagi, H. (2005) · Journal of Molecular Medicine

Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies

Cited by 413

Novel osteoclast signaling mechanisms

Shinohara, M., & Takayanagi, H. (2007) · Current Osteoporosis Reports

Bone Metabolism and DiseasesSignaling Pathways in Disease

Cited by 72