Lu, Zhike

N6-methyladenosine-dependent regulation of messenger RNA stability

Wang, X., Lu, Z., Gomez, A., Hon, G. C., Yue, Y., Han, D., Fu, Y., Parisien, M., Dai, Q., Jia, G., et al. (2014) · Nature

RNA modifications and cancerRNA Research and Splicing

Cited by 4,558

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

Zheng, G., Dahl, J. A., Niu, Y., Fedorcsak, P., Huang, C.-M., Li, C. J., Vågbø, C. B., Shi, Y., Wang, W.-L., Song, S.-H., et al. (2013) · Molecular Cell

RNA modifications and cancerRNA regulation and disease

Cited by 3,550

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

Wang, X., Zhao, B. S., Roundtree, I. A., Lu, Z., Han, D., Ma, H., Weng, X., Chen, K., Shi, H., & He, C. (2015) · Cell

RNA modifications and cancerRNA and protein synthesis mechanisms

Cited by 3,483

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

Liu, J., Yue, Y., Han, D., Wang, X., Fu, Y., Zhang, L., Jia, G., Yu, M., Lu, Z., Deng, X., et al. (2014) · Nature Chemical Biology

RNA modifications and cancerRNA regulation and disease

Cited by 3,433

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

Tan, M., Luo, H., Lee, S., Jin, F., Yang, J. S., Montellier, E., Buchou, T., Cheng, Z., Rousseaux, S., Rajagopal, N., et al. (2011) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 1,902

YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA

Shi, H., Wang, X., Lu, Z., Zhao, B. S., Ma, H., Hsu, P. J., Liu, C., & He, C. (2017) · Cell Research

RNA modifications and cancerRNA and protein synthesis mechanisms

Cited by 1,815

The diploid genome sequence of an Asian individual

Wang, J., Wang, W., Li, R., Li, Y., Tian, G., Goodman, L., Fan, W., Zhang, J., Li, J., Zhang, J., et al. (2008) · Nature

Genomics and Phylogenetic StudiesForensic and Genetic Research

Cited by 924

The first identification of lysine malonylation substrates and its regulatory enzyme

Peng, C., Lu, Z., Xie, Z., Cheng, Z., Chen, Y., Tan, M., Luo, H., Zhang, Y., He, W., Yang, K., et al. (2011) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsCancer-related gene regulation

Cited by 751

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Huang, H., Weng, H., Zhou, K., Wu, T., Zhao, B. S., Sun, M., Chen, Z., Deng, X., Xiao, G., Auer, F., et al. (2019) · Nature

RNA modifications and cancerEpigenetics and DNA Methylation

Cited by 677

m6A facilitates hippocampus-dependent learning and memory through YTHDF1

Shi, H., Zhang, X., Weng, Y.-L., Lu, Z., Liu, Y., Lu, Z., Li, J., Hao, P., Zhang, Y., Zhang, F., et al. (2018) · Nature

RNA modifications and cancerMemory and Neural Mechanisms

Cited by 546

Direct-seq: programmed gRNA scaffold for streamlined scRNA-seq in CRISPR screen

Song, Q., Ni, K., Liu, M., Li, Y., Wang, L., Wang, Y., Liu, Y., Yu, Z., Qi, Y., Lu, Z., et al. (2020) · Genome Biology

CRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics

Cited by 26

Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing

Li, J., Wu, P., Cao, Z., Huang, G., Lu, Z., Yan, J., Zhang, H., Zhou, Y., Liu, R., Chen, H., et al. (2024) · Cell Reports

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 26