Krishna, Murali C.

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues

Chen, Q., Espey, M. G., Krishna, M. C., Mitchell, J. B., Corpe, C. P., Buettner, G. R., Shacter, E., & Levine, M. (2005) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchCancer and biochemical research

Cited by 1,075

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

Chen, Q., Espey, M. G., Sun, A. Y., Pooput, C., Kirk, K. L., Krishna, M. C., Khosh, D. B., Drisko, J., & Levine, M. (2008) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchCancer and biochemical research

Cited by 854

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

Chen, Q., Espey, M. G., Sun, A. Y., Lee, J.-H., Krishna, M. C., Shacter, E., Choyke, P. L., Pooput, C., Kirk, K. L., Buettner, G. R., et al. (2007) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchRedox biology and oxidative stress

Cited by 676

Radioprotectors and mitigators of radiation-induced normal tissue injury

Citrin, D., Cotrim, A. P., Hyodo, F., Baum, B. J., Krishna, M. C., & Mitchell, J. B. (2010) · The Oncologist

Effects of Radiation ExposureRadiation Therapy and Dosimetry

Cited by 482

Absolute oxygen tension (pO2) in murine fatty and muscle tissue as determined by EPR

Matsumoto, A., Matsumoto, S., Sowers, A. L., Koscielniak, J. W., Trigg, N. J., Kuppusamy, P., Mitchell, J. B., Subramanian, S., Krishna, M. C., & Matsumoto, K. (2005) · Magnetic Resonance in Medicine

Electron Spin Resonance StudiesAdvanced MRI Techniques and Applications

Cited by 92

Imaging of glucose metabolism by 13C-MRI distinguishes pancreatic cancer subtypes in mice

Kishimoto, S., Brender, J. R., Crooks, D. R., Matsumoto, S., Seki, T., Oshima, N., Merkle, H., Lin, P., Reed, G., Chen, A. P., et al. (2019) · eLife

Advanced NMR Techniques and ApplicationsCancer, Hypoxia, and Metabolism

Cited by 41

Molecular imaging of the tumor microenvironment reveals the relationship between tumor oxygenation, glucose uptake, and glycolysis in pancreatic ductal adenocarcinoma

Yamamoto, K., Brender, J. R., Seki, T., Kishimoto, S., Oshima, N., Choudhuri, R., Adler, S. S., Jagoda, E. M., Saito, K., Devasahayam, N., et al. (2020) · Cancer Research

Cancer, Hypoxia, and MetabolismMedical Imaging Techniques and Applications

Cited by 37

Stable Isotope- and Mass Spectrometry-based Metabolomics as Tools in Drug Metabolism: A Study Expanding Tempol Pharmacology

Li, F., Pang, X., Krausz, K. W., Jiang, C., Chen, C., Cook, J. A., Krishna, M. C., Mitchell, J. B., Gonzalez, F. J., & Patterson, A. D. (2013) · Journal of Proteome Research

Metabolomics and Mass Spectrometry StudiesPharmacogenetics and Drug Metabolism

Cited by 31

In Vivo Measurement of Tissue Oxygen Using Electron Paramagnetic Resonance Spectroscopy with Oxygen-Sensitive Paramagnetic Particle, Lithium Phthalocyanine

Hyodo, F., Matsumoto, S., Hyodo, E., Matsumoto, A., Matsumoto, K., & Krishna, M. C. (2010) · Methods in molecular biology

Electron Spin Resonance StudiesAnalytical Chemistry and Sensors

Cited by 5