Simpson, Evan R.

Effect of testosterone and estradiol in a man with aromatase deficiency

Carani, C., Qin, K., Simoni, M., Faustini-Fustini, M., Serpente, S., Boyd, J., Korach, K. S., & Simpson, E. R. (1997) · New England Journal of Medicine

Sexual Differentiation and DisordersEstrogen and related hormone effects

Cited by 1,151

Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene

Fisher, C. R., Graves, K. H., Parlow, A. F., & Simpson, E. R. (1998) · Proceedings of the National Academy of Sciences

Estrogen and related hormone effectsSexual Differentiation and Disorders

Cited by 867

Aromatase—a brief overview

Simpson, E. R., Clyne, C., Rubin, G., Boon, W. C., Robertson, K., Britt, K., Speed, C., & Jones, M. (2002) · Annual Review of Physiology

Estrogen and related hormone effectsPhytoestrogen effects and research

Cited by 773

Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity

Jones, M. E. E., Thorburn, A. W., Britt, K. L., Hewitt, K. N., Wreford, N. G., Proietto, J., Oz, O. K., Leury, B. J., Robertson, K. M., Yao, S., et al. (2000) · Proceedings of the National Academy of Sciences

Estrogen and related hormone effectsRegulation of Appetite and Obesity

Cited by 729

Control of mammary stem cell function by steroid hormone signalling

Asselin-Labat, M.-L., Vaillant, F., Sheridan, J. M., Pal, B., Wu, D., Simpson, E. R., Yasuda, H., Smyth, G. K., Martin, T. J., Lindeman, G. J., et al. (2010) · Nature

Estrogen and related hormone effectsCancer Cells and Metastasis

Cited by 693

Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH

Simpson, E. R., & Waterman, M. R. (1988) · Annual Review of Physiology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 506

Female androgen insufficiency: the princeton consensus statement on definition, classification, and assessment

Bachmann, G., Bancroft, J., Braunstein, G., Burger, H., Davis, S., Dennerstein, L., Goldstein, I., Guay, A., Leiblum, S., Lobo, R., et al. (2002) · Fertility and Sterility

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 444

17α-Hydroxylase/17,20 lyase deficiency: from clinical investigation to molecular definition

YANASE, T., SIMPSON, E. R., & WATERMAN, M. R. (1991) · Endocrine Reviews

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 390

Expression of Bovine 17α-Hydroxylase Cytochrome P-450 cDNA in Nonsteroidogenic (COS 1) Cells

Zuber, M. X., Simpson, E. R., & Waterman, M. R. (1986) · Science

Steroid Chemistry and BiochemistryAdrenal Hormones and Disorders

Cited by 388

The role of local estrogen Biosynthesis in males and females

Simpson, E., Rubin, G., Clyne, C., Robertson, K., O’Donnell, L., Jones, M., & Davis, S. (2000) · Trends in Endocrinology & Metabolism

Estrogen and related hormone effectsHormonal and reproductive studies

Cited by 249

Of mice and men: the evolving phenotype of aromatase deficiency

Jones, M. E. E., Chin Boon, W., Proietto, J., & Simpson, E. R. (2006) · Trends in Endocrinology & Metabolism

Sexual Differentiation and DisordersEstrogen and related hormone effects

Cited by 193

Aromatase: biologic relevance of tissue-specific expression

Simpson, E. R. (2004) · Seminars in Reproductive Medicine

Estrogen and related hormone effectsPhytoestrogen effects and research

Cited by 190

Aromatase-deficient (ArKO) mice accumulate excess adipose tissue

Jones, M. E. E., Thorburn, A. W., Britt, K. L., Hewitt, K. N., Misso, M. L., Wreford, N. G., Proietto, J., Oz, O. K., Leury, B. J., Robertson, K. M., et al. (2001) · The Journal of Steroid Biochemistry and Molecular Biology

Estrogen and related hormone effectsRegulation of Appetite and Obesity

Cited by 141

Genetic or enzymatic disruption of aromatase inhibits the growth of ectopic uterine tissue

Fang, Z., Yang, S., Gurates, B., Tamura, M., Simpson, E., Evans, D., & Bulun, S. E. (2002) · The Journal of Clinical Endocrinology & Metabolism

Endometriosis Research and TreatmentEstrogen and related hormone effects

Cited by 91

Aromatase activity of membrane fractions of human adipose tissue stromal cells and adipocytes

CLELAND, W. H., MENDELSON, C. R., & SIMPSON, E. R. (1983) · Endocrinology

Estrogen and related hormone effectsLipid metabolism and biosynthesis

Cited by 86

Bovine steroid 21-hydroxylase: regulation of biosynthesis

John, M. E., Okamura, T., Dee, A., Adler, B., John, M. C., White, P. C., Simpson, E. R., & Waterman, M. R. (1986) · Biochemistry

Adrenal Hormones and DisordersHormonal Regulation and Hypertension

Cited by 61

Molecular basis of apparent isolated 17,20-lyase deficiency: compound heterozygous mutations in the C-terminal region (Arg(496) → Cys, Gln(461) → Stop) actually cause combined 17α-hydroxylase/17,20-lyase deficiency

Yanase, T., Waterman, M. R., Zachmann, M., Winter, J. S. D., Simpson, E. R., & Kagimoto, M. (1992) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 50

Hepatic Glucose Intolerance Precedes Hepatic Steatosis in the Male Aromatase Knockout (ArKO) Mouse

Van Sinderen, M. L., Steinberg, G. R., Jørgensen, S. B., To, S. Q., Knower, K. C., Clyne, C. D., Honeyman, J., Chow, J. D., Herridge, K. A., Jones, M. E. E., et al. (2014) · PLoS ONE

Estrogen and related hormone effectsDiet, Metabolism, and Disease

Cited by 26