Brewer, H. Bryan

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

Rust, S., Rosier, M., Funke, H., Real, J., Amoura, Z., Piette, J.-C., Deleuze, J.-F., Brewer, H. B., Duverger, N., Denèfle, P., et al. (1999) · Nature Genetics

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 1,433

Cholesterol Efflux and Atheroprotection: Advancing the Concept of Reverse Cholesterol Transport

Rosenson, R. S., Brewer, H. B., Davidson, W. S., Fayad, Z. A., Fuster, V., Goldstein, J., Hellerstein, M., Jiang, X.-C., Phillips, M. C., Rader, D. J., et al. (2012) · Circulation

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 953

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

Ma, J., Yee, A., Brewer, H. B., Das, S., & Potter, H. (1994) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 871

Dysfunctional HDL and atherosclerotic cardiovascular disease

Rosenson, R. S., Brewer, H. B., Ansell, B. J., Barter, P., Chapman, M. J., Heinecke, J. W., Kontush, A., Tall, A. R., & Webb, N. R. (2016) · Nature Reviews Cardiology

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 822

Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial

Nicholls, S. J., Brewer, H. B., Kastelein, J. J. P., Krueger, K. A., Wang, M.-D., Shao, M., Hu, B., McErlean, E., & Nissen, S. E. (2011) · JAMA

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 410

Abnormal in vivo metabolism of apolipoprotein E4 in humans.

Gregg, R. E., Zech, L. A., Schaefer, E. J., Stark, D., Wilson, D., & Brewer, H. B. (1986) · Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 345

Familial apolipoprotein E deficiency.

Schaefer, E. J., Gregg, R. E., Ghiselli, G., Forte, T. M., Ordovas, J. M., Zech, L. A., & Brewer, H. B. (1986) · Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 313

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

Guo, G. L., Lambert, G., Negishi, M., Ward, J. M., Brewer, H. B., Kliewer, S. A., Gonzalez, F. J., & Sinal, C. J. (2003) · Journal of Biological Chemistry

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 312

The impact of proprotein convertase subtilisin-kexin type 9 serine protease inhibitors on lipid levels and outcomes in patients with primary hypercholesterolaemia: a network meta-analysis

Lipinski, M. J., Benedetto, U., Escarcega, R. O., Biondi-Zoccai, G., Lhermusier, T., Baker, N. C., Torguson, R., Brewer, H. B., & Waksman, R. (2016) · European Heart Journal

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 256

Type III Hyperlipoproteinemia: Diagnosis, Molecular Defects, Pathology, and Treatment

BREWER, H. B., ZECH, L. A., GREGG, R. E., SCHWARTZ, D., & SCHAEFER, E. J. (1983) · Annals of Internal Medicine

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 226

Alzheimer Aβ neurotoxicity: Promotion by antichymotrypsin, ApoE4; inhibition by Aβ-related peptides

Ma, J., Brewer, H. B., & Potter, H. (1996) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 108

Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells

Lalanne, F., Lambert, G., Amar, M. J. A., Chétiveaux, M., Zaïr, Y., Jarnoux, A.-L., Ouguerram, K., Friburg, J., Seidah, N. G., Brewer, H. B., et al. (2005) · Journal of Lipid Research

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 104

Apolipoprotein E metabolism in normolipoproteinemic human subjects.

Gregg, R., Zech, L., Schaefer, E., & Brewer, H. (1984) · Journal of Lipid Research

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 90

Impact of Low High-Density Lipoproteins on In-Hospital Events and One-Year Clinical Outcomes in Patients With Non–ST-Elevation Myocardial Infarction Acute Coronary Syndrome Treated With Drug-Eluting Stent Implantation

Wolfram, R. M., Brewer, H. B., Xue, Z., Satler, L. F., Pichard, A. D., Kent, K. M., & Waksman, R. (2006) · The American Journal of Cardiology

Coronary Interventions and DiagnosticsLipoproteins and Cardiovascular Health

Cited by 86

Apolipoprotein E-1Harrisburg: a new variant of apolipoprotein E dominantly associated with type III hyperlipoproteinemia.

Mann, W. A., Gregg, R. E., Sprecher, D. L., & Brewer, H. B. (1989) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 75

Metabolism of high density lipoprotein subfractions and constituents in Tangier disease following the infusion of high density lipoproteins.

Schaefer, E. J., Anderson, D. W., Zech, L. A., Lindgren, F. T., Bronzert, T. B., Rubalcaba, E. A., & Brewer, H. B. (1981) · Journal of Lipid Research

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 74

Apolipoprotein E-4Philadelphia (Glu13—-Lys,Arg145—-Cys). Homozygosity for two rare point mutations in the apolipoprotein E gene combined with severe type III hyperlipoproteinemia

Lohse, P., Mann, W. A., Stein, E. A., & Brewer, H. B. (1991) · Journal of Biological Chemistry

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

Cited by 54

Dominant expression of type III hyperlipoproteinemia. Pathophysiological insights derived from the structural and kinetic characteristics of ApoE-1 (Lys146-->Glu).

Mann, W. A., Lohse, P., Gregg, R. E., Ronan, R., Hoeg, J. M., Zech, L. A., & Brewer, H. B. (1995) · Journal of Clinical Investigation

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 28

High-Density Lipoprotein Metabolism

Brewer, H. B. (2009) · Clinical Lipidology

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 3