Cholesterol Efflux and Atheroprotection: Advancing the Concept of Reverse Cholesterol Transport

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

Cholesterol Treatment Trialists' (CTT) Collaboration (2010) · The Lancet · doi:10.1016/s0140-6736(10)61350-5 · Cited by 6,550 · see citing works

Biological, clinical and population relevance of 95 loci for blood lipids

Teslovich, T. M., Musunuru, K., Smith, A. V., Edmondson, A. C., Stylianou, I. M., Koseki, M., Pirruccello, J. P., Ripatti, S., Chasman, D. I., Willer, C. J., et al. (2010) · Nature · doi:10.1038/nature09270 · Cited by 3,487 · see citing works

Major lipids, apolipoproteins, and risk of vascular disease

The Emerging Risk Factors Collaboration* (2009) · JAMA · doi:10.1001/jama.2009.1619 · Cited by 2,731 · see citing works

The plasma lecithin:cholesterol acyltransferase reaction

Glomset, J. A. (1968) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43114-1 · Cited by 2,409 · see citing works

Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor

Acton, S. L., Rigotti, A., Landschulz, K. T., Xu, S., Hobbs, H. H., & Krieger, M. (1996) · Science · doi:10.1126/science.271.5248.518 · Cited by 2,347 · see citing works

Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis

Khera, A. V., Cuchel, M., de la Llera-Moya, M., Rodrigues, A., Burke, M. F., Jafri, K., French, B. C., Phillips, J. A., Mucksavage, M. L., Wilensky, R. L., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1001689 · Cited by 1,943 · see citing works

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Janowski, B. A., Willy, P. J., Devi, T. R., Falck, J. R., & Mangelsdorf, D. J. (1996) · Nature · doi:10.1038/383728a0 · Cited by 1,754 · see citing works

Effect of Recombinant ApoA-I Milano on Coronary Atherosclerosis in Patients With Acute Coronary Syndromes: A Randomized Controlled Trial

Nissen, S. E., Tsunoda, T., Tuzcu, E. M., Schoenhagen, P., Cooper, C. J., Yasin, M., Eaton, G. M., Lauer, M. A., Sheldon, W. S., Grines, C. L., et al. (2003) · JAMA · doi:10.1001/jama.290.17.2292 · Cited by 1,707 · see citing works

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

Rayner, K. J., Suárez, Y., Dávalos, A., Parathath, S., Fitzgerald, M. L., Tamehiro, N., Fisher, E. A., Moore, K. J., & Fernández-Hernando, C. (2010) · Science · doi:10.1126/science.1189862 · Cited by 1,260 · see citing works

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

Wang, N., Lan, D., Chen, W., Matsuura, F., & Tall, A. R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403506101 · Cited by 1,059 · see citing works

Sterol-dependent Transactivation of theABC1 Promoter by the Liver X Receptor/Retinoid X Receptor

Costet, P., Luo, Y., Wang, N., & Tall, A. R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003337200 · Cited by 981 · see citing works

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

Najafi-Shoushtari, S. H., Kristo, F., Li, Y., Shioda, T., Cohen, D. E., Gerszten, R. E., & Näär, A. M. (2010) · Science · doi:10.1126/science.1189123 · Cited by 957 · see citing works

Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

Vaisar, T., Pennathur, S., Green, P. S., Gharib, S. A., Hoofnagle, A. N., Cheung, M. C., Byun, J., Vuletic, S., Kassim, S., Singh, P., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci26206 · Cited by 942 · see citing works

Cholesteryl Ester Transfer Protein

Barter, P. J., Brewer, H. B., Chapman, M. J., Hennekens, C. H., Rader, D. J., & Tall, A. R. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000054658.91146.64 · Cited by 868 · see citing works

Increased High-Density Lipoprotein Levels Caused by a Common Cholesteryl-Ester Transfer Protein Gene Mutation

Inazu, A., Brown, M. L., Hesler, C. B., Agellon, L. B., Koizumi, J., Takata, K., Maruhama, Y., Mabuchi, H., & Tall, A. R. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011013231803 · Cited by 862 · see citing works

Functionally Defective High-Density Lipoprotein: A New Therapeutic Target at the Crossroads of Dyslipidemia, Inflammation, and Atherosclerosis

Kontush, A., & Chapman, M. J. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.1 · Cited by 752 · see citing works

A protein cofactor of lecithin:Cholesterol acyltransferase

Fielding, C. J., Shore, V. G., & Fielding, P. E. (1972) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(72)90776-0 · Cited by 728 · see citing works

Effects of Reconstituted High-Density Lipoprotein Infusions on Coronary Atherosclerosis A Randomized Controlled Trial

Tardif, J. (2007) · JAMA · doi:10.1001/jama.297.15.jpc70004 · Cited by 724 · see citing works

Scavenger Receptor BI Promotes High Density Lipoprotein-mediated Cellular Cholesterol Efflux

Ji, Y. I., Jian, B., Wang, N., Sun, Y., Moya, M. D. L. L., Phillips, M. C., Rothblat, G. H., Swaney, J. B., & Tall, A. R. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.34.20982 · Cited by 694 · see citing works

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

Rayner, K. J., Sheedy, F. J., Esau, C. C., Hussain, F. N., Temel, R. E., Parathath, S., van Gils, J. M., Rayner, A. J., Chang, A. N., Suarez, Y., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci57275 · Cited by 690 · cited 1× · see citing works

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

Laffitte, B. A., Repa, J. J., Joseph, S. B., Wilpitz, D. C., Kast, H. R., Mangelsdorf, D. J., & Tontonoz, P. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.507 · Cited by 683 · see citing works

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

Rader, D. J., Alexander, E. T., Weibel, G. L., Billheimer, J. T., & Rothblat, G. H. (2008) · Journal of Lipid Research · doi:10.1194/jlr.r800088-jlr200 · Cited by 597 · see citing works

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo

Wang, X., Collins, H. L., Ranalletta, M., Fuki, I. V., Billheimer, J. T., Rothblat, G. H., Tall, A. R., & Rader, D. J. (2007) · Journal of Clinical Investigation · doi:10.1172/jci32057 · Cited by 593 · see citing works

miR-33 links SREBP-2 induction to repression of sterol transporters

Marquart, T. J., Allen, R. M., Ory, D. S., & Baldán, Á. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005191107 · Cited by 562 · see citing works

A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum.

Chapman, M. J., Goldstein, S., Lagrange, D., & Laplaud, P. M. (1981) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)35376-1 · Cited by 553 · see citing works

Mechanisms and consequences of cellular cholesterol exchange and transfer

Phillips, M. C., Johnson, W. J., & Rothblat, G. H. (1987) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(87)90013-x · Cited by 541 · see citing works

HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis

Tall, A. R., Yvan-Charvet, L., Terasaka, N., Pagler, T., & Wang, N. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.03.001 · Cited by 540 · see citing works

Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial

Fayad, Z. A., Mani, V., Woodward, M., Kallend, D. G., Abt, M., Burgess, T., Fuster, V., Ballantyne, C. M., Stein, E. A., Tardif, J., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)61383-4 · Cited by 536 · see citing works

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

Yvan-Charvet, L., Ranalletta, M., Wang, N., Han, S., Terasaka, N., Li, R., Welch, C., & Tall, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci33372 · Cited by 536 · see citing works

A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits

Okamoto, H., Yonemori, F., Wakitani, K., Minowa, T., Maeda, K., & Shinkai, H. (2000) · Nature · doi:10.1038/35018119 · Cited by 532 · see citing works

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

Brunham, L. R. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27352 · Cited by 519 · see citing works

Charting the Fate of the “Good Cholesterol”: Identification and Characterization of the High-Density Lipoprotein Receptor SR-BI

Krieger, M. (1999) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.68.1.523 · Cited by 517 · see citing works

HDL Measures, Particle Heterogeneity, Proposed Nomenclature, and Relation to Atherosclerotic Cardiovascular Events

Rosenson, R. S., Brewer, H. B., Chapman, M. J., Fazio, S., Hussain, M. M., Kontush, A., Krauss, R. M., Otvos, J. D., Remaley, A. T., & Schaefer, E. J. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.155333 · Cited by 511 · see citing works

Apolipoprotein L-I is the trypanosome lytic factor of human serum

Vanhamme, L., Paturiaux-Hanocq, F., Poelvoorde, P., Nolan, D. P., Lins, L., Abbeele, J. V. D., Pays, A., Tebabi, P., Xong, H. V., Jacquet, A., et al. (2003) · Nature · doi:10.1038/nature01461 · Cited by 501 · see citing works

A novel endothelial-derived lipase that modulates HDL metabolism

Jaye, M., Lynch, K. J., Krawiec, J. A., Marchadier, D. H. L., Maugeais, C., Doan, K. N., South, V., Amin, D., Perrone, M. H., & Rader, D. J. (1999) · Nature Genetics · doi:10.1038/7766 · Cited by 499 · see citing works

Dissociation of tissue uptake of cholesterol ester from that of apoprotein A-I of rat plasma high density lipoprotein: selective delivery of cholesterol ester to liver, adrenal, and gonad.

Glass, C. K., Pittman, R. C., Weinstein, D. B., & Steinberg, D. H. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.17.5435 · Cited by 491 · see citing works

Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins

Brown, M. L., Inazu, A., Hesler, C. B., Agellon, L. B., Mann, C., Whitlock, M. E., Marcel, Y. L., Milne, R. W., Koizumi, J., Mabuchi, H., et al. (1989) · Nature · doi:10.1038/342448a0 · Cited by 467 · see citing works

Increased Inflammatory Gene Expression in ABC Transporter–Deficient Macrophages

Yvan‐Charvet, L., Welch, C. L., Pagler, T. A., Ranalletta, M., Lamkanfi, M., Han, S., Ishibashi, M., Li, R., Wang, N., & Tall, A. R. (2008) · Circulation · doi:10.1161/circulationaha.108.793869 · Cited by 456 · see citing works

Efficacy and Safety of a Novel Cholesteryl Ester Transfer Protein Inhibitor, JTT-705, in Humans

de Grooth, G. J., Kuivenhoven, J. A., Stalenhoef, A. F. H., Graaf, J. D., Zwinderman, A. H., Posma, J. L., van Tol, A., & Kastelein, J. J. P. (2002) · Circulation · doi:10.1161/01.cir.0000015857.31889.7b · Cited by 454 · see citing works

Small, Dense HDL Particles Exert Potent Protection of Atherogenic LDL Against Oxidative Stress

Kontush, A., Chantepie, S., & Chapman, M. J. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000091338.93223.e8 · Cited by 452 · see citing works

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

Timmins, J. M., Lee, J.-Y., Boudyguina, E., Kluckman, K. D., Brunham, L. R., Mulya, A., Gebre, A. K., Coutinho, J. M., Colvin, P. L., Smith, T. L., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23915 · Cited by 447 · see citing works

Overexpression of Apolipoprotein A-I Promotes Reverse Transport of Cholesterol From Macrophages to Feces In Vivo

Zhang, Y., Zanotti, I., Reilly, M. P., Glick, J. M., Rothblat, G. H., & Rader, D. J. (2003) · Circulation · doi:10.1161/01.cir.0000086981.09834.e0 · Cited by 435 · see citing works

Proteomic Analysis of Defined HDL Subpopulations Reveals Particle-Specific Protein Clusters: Relevance to Antioxidative Function

Davidson, W. S., Silva, R. A. G. D., Chantepie, S., Lagor, W. R., Chapman, M. J., & Kontush, A. (2009) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.109.186031 · Cited by 415 · see citing works

Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels

Jiang, X., Bruce, C., Mar, J., Lin, M., Ji, Y. I., Francone, O. L., & Tall, A. R. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5578 · Cited by 393 · see citing works

The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages

de la Llera-Moya, M., Drazul‐Schrader, D., Asztalos, B. F., Cuchel, M., Rader, D. J., & Rothblat, G. H. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.199158 · Cited by 385 · see citing works

MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 ( <i>Srebp2</i> ) regulates HDL in vivo

Horie, T., Ono, K., Horiguchi, M., Nishi, H., Nakamura, T., Nagao, K., Kinoshita, M., Kuwabara, Y., Marusawa, H., Iwanaga, Y., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1008499107 · Cited by 384 · see citing works

Raising High-Density Lipoprotein in Humans Through Inhibition of Cholesteryl Ester Transfer Protein

Clark, R. W., Sutfin, T. A., Ruggeri, R. B., Willauer, A. T., Sugarman, E. D., Magnus-Aryitey, G., Cosgrove, P. G., Sand, T. M., Wester, R. T., Williams, J. A., et al. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000118278.21719.17 · Cited by 370 · see citing works

High-density lipoprotein heterogeneity and function in reverse cholesterol transport

Rothblat, G. H., & Phillips, M. C. (2010) · Current Opinion in Lipidology · doi:10.1097/mol.0b013e328338472d · Cited by 341 · see citing works

Mechanism of ATP-binding Cassette Transporter A1-mediated Cellular Lipid Efflux to Apolipoprotein A-I and Formation of High Density Lipoprotein Particles

Vedhachalam, C., Duong, P. T., Nickel, M., Nguyen, D., Dhanasekaran, P., Saito, H., Rothblat, G. H., Lund‐Katz, S., & Phillips, M. C. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704590200 · Cited by 337 · see citing works

The roles of different pathways in the release of cholesterol from macrophages

Adorni, M. P., Zimetti, F., Billheimer, J. T., Wang, N., Rader, D. J., Phillips, M. C., & Rothblat, G. H. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700274-jlr200 · Cited by 332 · see citing works

Cellular Localization and Trafficking of the Human ABCA1 Transporter

Neufeld, E. B., Remaley, A. T., Demosky, S. J., Stonik, J. A., Cooney, A. M., Comly, M., Dwyer, N. K., Zhang, M., Blanchette‐Mackie, J., Santamarina-Fojo, S., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103264200 · Cited by 331 · see citing works

Genetic Variant of the Scavenger Receptor BI in Humans

Vergeer, M., Korporaal, S. J. A., Franssen, R., Meurs, I., Out, R., Hovingh, G. K., Hoekstra, M., Sierts, J. A., Dallinga-Thie, G. M., Motazacker, M. M., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa0907687 · Cited by 317 · see citing works

Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

Zhang, Y. (2005) · Journal of Clinical Investigation · doi:10.1172/jci25327 · Cited by 307 · see citing works

Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I

Rye, K., & Barter, P. J. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000104029.74961.f5 · Cited by 307 · see citing works

Some properties of a cholesterol esterifying enzyme in human plasma

Glomset, J. A., & Wright, J. L. (1964) · Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects · doi:10.1016/0926-6569(64)90215-9 · Cited by 299 · see citing works

HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway

Matsuura, F. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27602 · Cited by 293 · see citing works

Scavenger Receptor Class B Type I as a Mediator of Cellular Cholesterol Efflux to Lipoproteins and Phospholipid Acceptors

Jian, B., de la Llera-Moya, M., Ji, Y. I., Wang, N., Phillips, M. C., Swaney, J. B., Tall, A. R., & Rothblat, G. H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.10.5599 · Cited by 288 · see citing works

Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies

Krishna, R., Anderson, M. S., Bergman, A. J., Jin, B., Fallon, M. S., Côté, J., Rosko, K., Chavez-Eng, C. M., Lutz, R., Bloomfield, D. M., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61813-3 · Cited by 275 · see citing works

The Failure of Torcetrapib

Tall, A. R., Yvan‐Charvet, L., & Wang, N. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000256728.60226.77 · Cited by 268 · see citing works

ABCG1 Redistributes Cell Cholesterol to Domains Removable by High Density Lipoprotein but Not by Lipid-depleted Apolipoproteins

Vaughan, A. M., & Oram, J. F. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m505368200 · Cited by 266 · see citing works

Monocyte/macrophage expression of ABCA1 has minimal contribution to plasma HDL levels

Haghpassand, M., Bourassa, P.-A. K., Francone, O. L., & Aiello, R. J. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200112810 · Cited by 257 · see citing works

Characterization of the Human ABCG1 Gene

Kennedy, M. A., Venkateswaran, A., Tarr, P. T., Xénarios, I., Kudoh, J., Shimizu, N., & Edwards, P. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105863200 · Cited by 253 · see citing works

Lipoprotein cholesteryl ester production, transfer, and output in vivo in humans

Schwartz, C. C., VandenBroek, J. M., & Cooper, P. S. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m300511-jlr200 · Cited by 250 · see citing works

Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma

Huang, R., Silva, R. A. G. D., Jerome, W. G., Kontush, A., Chapman, M. J., Curtiss, L. K., Hodges, T. J., & Davidson, W. S. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2028 · Cited by 246 · see citing works

Genetic cholesteryl ester transfer protein deficiency caused by two prevalent mutations as a major determinant of increased levels of high density lipoprotein cholesterol.

Inazu, A., Jiang, X., Haraki, T., Yagi, K., KAMON, N., Koizumi, J., Mabuchi, H., Takeda, R., Takata, K., & Moriyama, Y. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117537 · Cited by 246 · see citing works

Lipoproteomics II: Mapping of proteins in high‐density lipoprotein using two‐dimensional gel electrophoresis and mass spectrometry

Karlsson, H., Leanderson, P., Tagesson, C., & Lindahl, M. G. (2005) · PROTEOMICS · doi:10.1002/pmic.200401010 · Cited by 240 · see citing works

ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice

Vaisman, B. L., Lambert, G. C., Amar, M. J., Joyce, C. W., Ito, T., Shamburek, R. D., Cain, W. J., Fruchart‐Najib, J., Neufeld, E. D., Remaley, A. T., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12517 · Cited by 240 · see citing works

Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics.

Hegele, R. A., Little, J. A., Vézina, C., Maguire, G. F., Tu, L., Wolever, T. S., Jenkins, D. J., & Connelly, P. W. (1993) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.13.5.720 · Cited by 239 · see citing works

Cholesterol Efflux Potential and Antiinflammatory Properties of High-Density Lipoprotein After Treatment With Niacin or Anacetrapib

Yvan‐Charvet, L., Kling, J., Pagler, T. A., Li, H., Hubbard, B. K., Fisher, T., Sparrow, C. P., Taggart, A. K. P., & Tall, A. R. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.207142 · Cited by 238 · see citing works

Overexpression of lecithin:cholesterol acyltransferase in transgenic rabbits prevents diet-induced atherosclerosis.

Hoeg, J. M., Santamarina-Fojo, S., Bérard, A. M., Cornhill, J. F., Herderick, E. E., Feldman, S. H., Haudenschild, C. C., Vaisman, B. L., Hoyt, R. F., Demosky, S. J., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11448 · Cited by 230 · see citing works

Effects of Cholesteryl Ester Transfer Protein Inhibition on High-Density Lipoprotein Subspecies, Apolipoprotein A-I Metabolism, and Fecal Sterol Excretion

Brousseau, M. E., Diffenderfer, M. R., Millar, J. S., Nartsupha, C., Asztalos, B. F., Welty, F. K., Wolfe, M. L., Rudling, M. J., Björkhem, I., Angelin, B., et al. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000161928.16334.dd · Cited by 229 · see citing works

Stimulation of Fecal Steroid Excretion After Infusion of Recombinant Proapolipoprotein A-I

Eriksson, M., Carlson, L. A., Miettinen, T. A., & Angelin, B. (1999) · Circulation · doi:10.1161/01.cir.100.6.594 · Cited by 227 · see citing works

A First-in-Man, Randomized, Placebo-Controlled Study to Evaluate the Safety and Feasibility of Autologous Delipidated High-Density Lipoprotein Plasma Infusions in Patients With Acute Coronary Syndrome

Waksman, R., Torguson, R., Kent, K. M., Pichard, A. D., Suddath, W. O., Satler, L. F., Martin, B. D., Perlman, T. J., Maltais, J. B., Weissman, N. J., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.12.067 · Cited by 225 · see citing works

Scavenger Receptor Class B Type I–Mediated Protection Against Atherosclerosis in LDL Receptor–Negative Mice Involves Its Expression in Bone Marrow–Derived Cells

Covey, S. D., Krieger, M., Wang, W., Penman, M., & Trigatti, B. L. (2003) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000083343.19940.a0 · Cited by 221 · see citing works

Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo

Jin, W., Millar, J. S., Broedl, U. C., Glick, J. M., & Rader, D. J. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16146 · Cited by 217 · see citing works

Lecithin-cholesterol acyltransferase in the metabolism of high-density lipoproteins

Jonas, A. (1991) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(91)90062-m · Cited by 216 · see citing works

Cholesteryl Ester Transfer Protein Inhibition, High-Density Lipoprotein Raising, and Progression of Coronary Atherosclerosis

Nicholls, S. J., Tuzcu, E. M., Brennan, D. M., Tardif, J., & Nissen, S. E. (2008) · Circulation · doi:10.1161/circulationaha.108.790733 · Cited by 213 · see citing works

Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes

Silva, R. A. G. D., Huang, R., Morris, J. C., Fang, J., Gracheva, E. O., Ren, G., Kontush, A., Jerome, W. G., Rye, K., & Davidson, W. S. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803626105 · Cited by 206 · see citing works

ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice

Vaisman, B. L., Lambert, G. C., Amar, M. J., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200112517 · Cited by 206 · see citing works

Human Plasma Phospholipid Transfer Protein Increases the Antiatherogenic Potential of High Density Lipoproteins in Transgenic Mice

van Haperen, R., van Tol, A., Vermeulen, P. S., Jauhiainen, M., van Gent, T., van den Berg, P., Ehnholm, S., Grosveld, F. G., van der Kamp, A., & de Crom, R. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.4.1082 · Cited by 204 · see citing works

Stimulation of Cholesterol Efflux by LXR Agonists in Cholesterol-Loaded Human Macrophages Is ABCA1-Dependent but ABCG1-Independent

Larrède, S., Quinn, C. M., Jessup, W., Frisdal, É., Olivier, M., Hsieh, V., Kim, M., Eck, M. V., Couvert, P., Carrié, A., et al. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.194548 · Cited by 202 · see citing works

Anti-inflammatory apoA-I-mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I

Lenten, B. J. V., Wagner, A. C., Jung, C., Ruchala, P. P., Waring, A. J., Lehrer, R. I., Watson, A. D., Hama, S. Y., Navab, M., Anantharamaiah, G. M., et al. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800075-jlr200 · Cited by 194 · see citing works

Characterization of nascent HDL particles and microparticles formed by ABCA1-mediated efflux of cellular lipids to apoA-I

Duong, P. T., Collins, H. L., Nickel, M., Lund‐Katz, S., Rothblat, G. H., & Phillips, M. C. (2006) · Journal of Lipid Research · doi:10.1194/jlr.m500531-jlr200 · Cited by 189 · see citing works

Phospholipid Transfer Protein Is Regulated by Liver X Receptors in Vivo

Cao, G., Beyer, T. P., Yang, X. P., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207187200 · Cited by 189 · see citing works

Myeloperoxidase: An Oxidative Pathway for Generating Dysfunctional High-Density Lipoprotein

Shao, B., Oda, M. N., Oram, J. F., & Heinecke, J. W. (2009) · Chemical Research in Toxicology · doi:10.1021/tx9003775 · Cited by 185 · see citing works

Imaging the Vulnerable Plaque

Vancraeynest, D., Pasquet, A., Roelants, V., Gerber, B. L., & Vanoverschelde, J. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.02.018 · Cited by 174 · see citing works

Proteomic analysis of high‐density lipoprotein

Rezaee, F., Casetta, B., Levels, J. H. M., Speijer, D., & Meijers, J. C. M. (2006) · PROTEOMICS · doi:10.1002/pmic.200500191 · Cited by 174 · see citing works

Putting cholesterol in its place: apoE and reverse cholesterol transport

Mahley, R. W. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28632 · Cited by 173 · see citing works

Endothelial Lipase Concentrations Are Increased in Metabolic Syndrome and Associated with Coronary Atherosclerosis

Badellino, K. O., Wolfe, M. L., Reilly, M. P., & Rader, D. J. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0030022 · Cited by 173 · see citing works

Increased Atherosclerosis in Mice Lacking Apolipoprotein A-I Attributable to Both Impaired Reverse Cholesterol Transport and Increased Inflammation

Moore, R. E., Navab, M., Millar, J. S., Zimetti, F., Hama, S. Y., Rothblat, G. H., & Rader, D. J. (2005) · Circulation Research · doi:10.1161/01.res.0000185320.82962.f7 · Cited by 173 · see citing works

Dual Role for Scavenger Receptor Class B, Type I on Bone Marrow-Derived Cells in Atherosclerotic Lesion Development

Eck, M. V., Bos, I. S. T., Hildebrand, R. B., Rij, B. T. V., & van Berkel, T. J. C. (2004) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63341-x · Cited by 172 · see citing works

Compromised LCAT Function Is Associated With Increased Atherosclerosis

Hovingh, G. K., Hutten, B. A., Holleboom, A. G., Petersen, W., Rol, P., Stalenhoef, A. F. H., Zwinderman, A. H., de Groot, E., Kastelein, J. J. P., & Kuivenhoven, J. A. (2005) · Circulation · doi:10.1161/circulationaha.105.540427 · Cited by 165 · see citing works

Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux

Sankaranarayanan, S., Oram, J. F., Asztalos, B. F., et al. (2008) · Journal of Lipid Research · doi:10.1194/jlr.m800362-jlr200 · Cited by 163 · see citing works

Dynamics of reverse cholesterol transport: protection against atherosclerosis

Sviridov, D., & Nestel, P. J. (2002) · Atherosclerosis · doi:10.1016/s0021-9150(01)00677-3 · Cited by 161 · see citing works

Impact of Short-Term Administration of High-Density Lipoproteins and Atorvastatin on Atherosclerosis in Rabbits

Nicholls, S. J., Cutri, B., Worthley, S. G., Kee, P. H., Rye, K.-A., Bao, S., & Barter, P. J. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000184760.95957.d6 · Cited by 154 · see citing works

Imaging of Atherosclerosis

Owen, D. R., Lindsay, A. C., Choudhury, R. P., & Fayad, Z. A. (2010) · Annual Review of Medicine · doi:10.1146/annurev-med-041709-133809 · Cited by 154 · see citing works

Lipoprotein metabolism in hepatic lipase deficiency: studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein.

Demant, T., Carlson, L. A., Holmquist, L., Karpe, F., Nilsson‐Ehle, P., Packard, C. J., & Shepherd, J. (1988) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38410-8 · Cited by 151 · see citing works

Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport

Niesor, E. J., Magg, C., Ogawa, N., Okamoto, H., von der Mark, E., Matile, H., Schmid, G., Clerc, R. G., Chaput, E., Blum‐Kaelin, D., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m008706 · Cited by 151 · see citing works

Phospholipid Transfer Protein Interacts with and Stabilizes ATP-binding Cassette Transporter A1 and Enhances Cholesterol Efflux from Cells

Oram, J. F., Wolfbauer, G., Vaughan, A. M., Tang, C., & Albers, J. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m310695200 · Cited by 148 · see citing works

The BioImage Study: Novel approaches to risk assessment in the primary prevention of atherosclerotic cardiovascular disease—study design and objectives

Muntendam, P., McCall, C. J., Sanz, J., Falk, E., & Fuster, V. (2010) · American Heart Journal · doi:10.1016/j.ahj.2010.02.021 · Cited by 146 · see citing works

Dose-Dependent Acceleration of High-Density Lipoprotein Catabolism by Endothelial Lipase

Maugeais, C., Tietge, U. J. F., Broedl, U. C., Marchadier, D. H. L., Cain, W. J., McCoy, M. G., Lund‐Katz, S., Glick, J. M., & Rader, D. J. (2003) · Circulation · doi:10.1161/01.cir.0000092889.24713.dc · Cited by 132 · see citing works

Analysis of Glomerulosclerosis and Atherosclerosis in Lecithin Cholesterol Acyltransferase-deficient Mice

Lambert, G. C., Sakai, N., Vaisman, B. L., Neufeld, E. B., Marteyn, B., Chan, C., Paigen, B. J., Lupia, E., Thomas, A., Striker, L. J., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008466200 · Cited by 131 · see citing works

The role of hepatic lipase in lipoprotein metabolism

Connelly, P. W. (1999) · Clinica Chimica Acta · doi:10.1016/s0009-8981(99)00105-9 · Cited by 130 · see citing works

Functional Lecithin: Cholesterol Acyltransferase Is Not Required for Efficient Atheroprotection in Humans

Calabresi, L., Baldassarre, D., Castelnuovo, S., Conca, P., Bocchi, L., Candini, C., Frigerio, B., Amato, M., Sirtori, C. R., Alessandrini, P., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.818143 · Cited by 130 · see citing works

Role of Hepatic Lipase and Endothelial Lipase in High-Density Lipoprotein—Mediated Reverse Cholesterol Transport

Annema, W., & Tietge, U. J. F. (2011) · Current Atherosclerosis Reports · doi:10.1007/s11883-011-0175-2 · Cited by 130 · see citing works

Effects of Acceptor Particle Size on the Efflux of Cellular Free Cholesterol

Davidson, W. S., Rodrigueza, W. V., Lund‐Katz, S., et al. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.29.17106 · Cited by 130 · see citing works

Functional Lecithin: Cholesterol Acyltransferase Is Not Required for Efficient Atheroprotection in Humans

Calabresi, L., Baldassarre, D., Castelnuovo, S., Conca, P., Bocchi, L., Candini, C., Frigerio, B., Amato, M., Sirtori, C. R., Alessandrini, P., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.848143 · Cited by 130 · see citing works

Regulation of Cellular Cholesterol Efflux by Lecithin:Cholesterol Acyltransferase Reaction through Nonspecific Lipid Exchange

Czarnecka, H., & Yokoyama, S. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.4.2023 · Cited by 124 · see citing works

D-4F, an Apolipoprotein A-I Mimetic Peptide, Inhibits the Inflammatory Response Induced by Influenza A Infection of Human Type II Pneumocytes

Lenten, B. J. V., Wagner, A. C., Navab, M., Anantharamaiah, G. M., Hui, E. K., Nayak, D. P., & Fogelman, A. M. (2004) · Circulation · doi:10.1161/01.cir.0000147232.75456.b3 · Cited by 116 · see citing works

5A Apolipoprotein Mimetic Peptide Promotes Cholesterol Efflux and Reduces Atherosclerosis in Mice

Amar, M. J., D’Souza, W., Turner, S., Demosky, S. J., Sviridov, D. O., Stonik, J. A., Luchoomun, J., Voogt, J. N., Hellerstein, M. K., Sviridov, D., et al. (2010) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.110.167890 · Cited by 114 · see citing works

Minimal Lipidation of Pre-β HDL by ABCA1 Results in Reduced Ability to Interact with ABCA1

Mulya, A., Lee, J., Gebre, A. K., Thomas, M. J., Colvin, P. L., & Parks, J. S. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.142455 · Cited by 113 · see citing works

Sphingomyelin Inhibits the Lecithin-Cholesterol Acyltransferase Reaction with Reconstituted High Density Lipoproteins by Decreasing Enzyme Binding

Bolin, D. J., & Jonas, A. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.32.19152 · Cited by 110 · see citing works

Role of sphingomyelin in the regulation of cholesterol esterification in the plasma lipoproteins. Inhibition of lecithin-cholesterol acyltransferase reaction.

Subbaiah, P. V., & Liu, M. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)80707-8 · Cited by 106 · see citing works

Distribution of phospholipid transfer protein in human plasma: presence of two forms of phospholipid transfer protein, one catalytically active and the other inactive

Oka, T., Kujiraoka, T., Ito, M., Egashira, T., Takahashi, S., Nanjee, M. N., Miller, N. E., Metso, J., Olkkonen, V. M., Ehnholm, C., et al. (2000) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31998-2 · Cited by 106 · see citing works

Deletion of ABCA1 and ABCG1 Impairs Macrophage Migration Because of Increased Rac1 Signaling

Pagler, T. A., Wang, M., Mondal, M., Murphy, A. J., Westerterp, M., Moore, K. J., Maxfield, F. R., & Tall, A. R. (2011) · Circulation Research · doi:10.1161/circresaha.110.228619 · Cited by 105 · see citing works

Lecithin Cholesterol Acyltransferase: An Anti- or Pro-atherogenic Factor?

Rousset, X., Shamburek, R. D., Vaisman, B. L., Amar, M. J., & Remaley, A. T. (2011) · Current Atherosclerosis Reports · doi:10.1007/s11883-011-0171-6 · Cited by 105 · see citing works

Phospholipid Transfer Protein Deficiency Impairs Apolipoprotein-B Secretion from Hepatocytes by Stimulating a Proteolytic Pathway through a Relative Deficiency of Vitamin E and an Increase in Intracellular Oxidants

Jiang, X.-C., Li, Z., Liu, R., Yang, X. P., Pan, M., Lagrost, L., Fisher, E. A., & Williams, K. J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500007200 · Cited by 102 · see citing works

Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1

Wellington, C. L., Brunham, L. R., Zhou, S., Singaraja, R. R., Visscher, H., Gelfer, A., Ross, C. J., James, E. R., Liu, G., Huber, M. T., et al. (2003) · Journal of Lipid Research · doi:10.1194/jlr.m300110-jlr200 · Cited by 100 · see citing works

Lipases and HDL metabolism

Jin, W., Marchadier, D. H. L., & Rader, D. J. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(02)00589-1 · Cited by 99 · see citing works

Biochemical characterization of cholesteryl ester transfer protein inhibitors

Ranalletta, M., Bierilo, K. K., Chen, Y., Milot, D. P., Chen, Q., Tung, E. C., Houde, C., Elowe, N. H., Garcia-Calvo, M. M., Porter, G., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m007468 · Cited by 97 · see citing works

Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo

Sacks, F. M., Rudel, L. L., Conner, A. P., Akeefe, H., Kostner, G. M., Baki, T. T., Rothblat, G. H., de la Llera-Moya, M., Asztalos, B. F., Perlman, T. J., et al. (2009) · Journal of Lipid Research · doi:10.1194/jlr.m800622-jlr200 · Cited by 96 · see citing works

Lecithin:Cholesterol Acyltransferase Deficiency Increases Atherosclerosis in the Low Density Lipoprotein Receptor and Apolipoprotein E Knockout Mice

Furbee, J. W., Sawyer, J. K., & Parks, J. S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109883200 · Cited by 91 · see citing works

Structure of Spheroidal HDL Particles Revealed by Combined Atomistic and Coarse-Grained Simulations

Catte, A., Patterson, J. C., Bashtovyy, D., et al. (2007) · Biophysical Journal · doi:10.1529/biophysj.107.115857 · Cited by 87 · see citing works

Impact of Combined Deficiency of Hepatic Lipase and Endothelial Lipase on the Metabolism of Both High-Density Lipoproteins and Apolipoprotein B–Containing Lipoproteins

Brown, R., Lagor, W. R., Sankaranaravanan, S., Yasuda, T., Quertermous, T., Rothblat, G. H., & Rader, D. J. (2010) · Circulation Research · doi:10.1161/circresaha.110.219188 · Cited by 86 · see citing works

The implications of the structure of the bactericidal/permeability-increasing protein on the lipid-transfer function of the cholesteryl ester transfer protein

Bruce, C., Beamer, L. J., & Tall, A. R. (1998) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(98)80118-8 · Cited by 86 · see citing works

Effect of Up-regulating Individual Steps in the Reverse Cholesterol Transport Pathway on Reverse Cholesterol Transport in Normolipidemic Mice

Alam, M. K., Meidell, R. S., & Spady, D. K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010230200 · Cited by 85 · see citing works

Mass spectrometry‐based analytical tools for the molecular protein characterization of human plasma lipoproteins

Heller, M., Stalder, D., Schlappritzi, E., Hayn, G., Matter, U., & Haeberli, A. (2005) · PROTEOMICS · doi:10.1002/pmic.200401233 · Cited by 83 · see citing works

The concept of apolipoprotein-defined lipoprotein families and its clinical significance

Alaupovic, P. (2003) · Current Atherosclerosis Reports · doi:10.1007/s11883-003-0036-8 · Cited by 81 · see citing works

Scavenger receptor BI modulates platelet reactivity and thrombosis in dyslipidemia

Ma, Y., Ashraf, M. Z., & Podrez, E. A. (2010) · Blood · doi:10.1182/blood-2010-02-268508 · Cited by 72 · see citing works

Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice

Nong, Z., Navarro, H. G., Amar, M. J., Freeman, L. A., Knapper, C. L., Neufeld, E. B., Paigen, B. J., Hoyt, R. F., Fruchart‐Najib, J., & Santamarina-Fojo, S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci16484 · Cited by 59 · see citing works

Overexpression of human lecithin:cholesterol acyltransferase in cholesterol-fed rabbits: LDL metabolism and HDL metabolism are affected in a gene dose-dependent manner

Brousseau, M., Santamarina-Fojo, S., Vaisman, B. L., Applebaum-Bowden, D. M., Bérard, A. M., Talley, G. D., Brewer, H. B., & Hoeg, J. M. (1997) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)30038-9 · Cited by 55 · see citing works

Cholesterol Efflux from Macrophage Foam Cells Is Enhanced by Active Phospholipid Transfer Protein through Generation of Two Types of Acceptor Particles

Vikstedt, R., Metso, J., Hakala, J. K., Olkkonen, V. M., Ehnholm, C., & Jauhiainen, M. (2007) · Biochemistry · doi:10.1021/bi700833h · Cited by 54 · see citing works

SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL

Yvan‐Charvet, L., Pagler, T. A., Wang, N., Senokuchi, T., Brundert, M., Li, H., Rinninger, F., & Tall, A. R. (2007) · Journal of Lipid Research · doi:10.1194/jlr.m700200-jlr200 · Cited by 54 · see citing works

Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal liver cells

Fluiter, K., & van Berkel, T. J. C. (1997) · Biochemical Journal · doi:10.1042/bj3260515 · Cited by 51 · see citing works

Cholesteryl Ester Transfer Protein Expression Partially Attenuates the Adverse Effects of SR-BI Receptor Deficiency on Cholesterol Metabolism and Atherosclerosis

Bouhassani, M. E., Gilibert, S., Moreau, M., Saint-Charles, F., Tréguier, M., Potì, F., Chapman, M. J., Goff, W. L., Lesnik, P., & Huby, T. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.220483 · Cited by 49 · see citing works

Selective uptake of HDL cholesteryl esters and cholesterol efflux from mouse peritoneal macrophages independent of SR-BI

Brundert, M., Heeren, J., Bahar-Bayansar, M., Ewert, A., Moore, K. J., & Rinninger, F. (2006) · Journal of Lipid Research · doi:10.1194/jlr.m600136-jlr200 · Cited by 47 · see citing works

LCAT Modulates Atherogenic Plasma Lipoproteins and the Extent of Atherosclerosis Only in the Presence of Normal LDL Receptors in Transgenic Rabbits

Brousseau, M. E., Kauffman, R. D., Herderick, E. E., Demosky, S. J., Evans, W., Marcovina, S. M., Santamarina-Fojo, S., Brewer, H. B., & Hoeg, J. M. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.2.450 · Cited by 47 · see citing works

Worsening of Diet-Induced Atherosclerosis in a New Model of Transgenic Rabbit Expressing the Human Plasma Phospholipid Transfer Protein

Masson, D., Deckert, V., Gautier, T., Klein, A., Desrumaux, C. M., Viglietta, C., de Barros, J.-P. P., Guern, N. L., Grober, J., Labbé, J., et al. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.215756 · Cited by 44 · see citing works

Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice

Nong, Z., Navarro, H. G., Amar, M. J., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200316484 · Cited by 44 · see citing works

Elevation of systemic PLTP, but not macrophage-PLTP, impairs macrophage reverse cholesterol transport in transgenic mice

Samyn, H., Moerland, M., van Gent, T., van Haperen, R., Grosveld, F. G., van Tol, A., & de Crom, R. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.10.020 · Cited by 41 · see citing works

Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism

Ruel, I. L., Couture, P., Cohn, J. S., Bensadoun, A., Marcil, M., & Lamarche, B. (2004) · Journal of Lipid Research · doi:10.1194/jlr.m400090-jlr200 · Cited by 41 · see citing works

Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein

Amar, M. J., Shamburek, R. D., Vaisman, B. L., Knapper, C. L., Föger, B., Hoyt, R. F., Santamarina-Fojo, S., Brewer, H. B., & Remaley, A. T. (2009) · Metabolism · doi:10.1016/j.metabol.2008.11.019 · Cited by 40 · see citing works

Effects of sphingomyelin on apolipoprotein E- and lipoprotein lipase-mediated cell uptake of lipid particles

Morita, S. (2003) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(02)00365-7 · Cited by 37 · see citing works

Quantitation of the active and low-active forms of human plasma phospholipid transfer protein by ELISA

Siggins, S., Kärkkäinen, M., Tenhunen, J., Metso, J., Tahvanainen, E., Olkkonen, V. M., Jauhiainen, M., & Ehnholm, C. (2004) · Journal of Lipid Research · doi:10.1194/jlr.d300023-jlr200 · Cited by 33 · see citing works

Active plasma phospholipid transfer protein is associated with apoA-I- but not apoE-containing lipoproteins

Cheung, M. C., & Albers, J. J. (2006) · Journal of Lipid Research · doi:10.1194/jlr.m600042-jlr200 · Cited by 31 · see citing works

Hepatic lipase: Friend or foe and under what circumstances?

Jansen, H. (2004) · Current Atherosclerosis Reports · doi:10.1007/s11883-004-0044-3 · Cited by 25 · see citing works

Abstract 5920: Lecithin Cholesterol Acyltransferase Promotes Reverse Cholesterol Transport and Attenuates Atherosclerosis Progression in New Zealand White Rabbits

Zhou, M., Sawyer, J. K., Kelley, K. L., et al. (2009) · Circulation · Cited by 15 · see citing works

Different phospholipid transfer protein complexes contribute to the variation in plasma PLTP specific activity

Cheung, M. C., Wolfbauer, G., & Albers, J. J. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.02.001 · Cited by 8 · see citing works

The Year in Intracoronary Imaging

Muller, J. E., Weissman, N. J., & Tuzcu, E. M. (2010) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2010.05.010 · Cited by 5 · see citing works

P216 CARRIERS OF LCAT GENE MUTATIONS HAVE INCREASED ATHEROSCLEROSIS: A 3.0 TESLA MRI STUDY

Holleboom, A. G., Duivenvoorden, R., van den Bogaard, B., et al. (2010) · Atherosclerosis Supplements · doi:10.1016/s1567-5688(10)70283-x · Cited by 2 · see citing works

Mechanisms and regulation of cholesterol homeostasis

Luo, J., Yang, H., & Song, B.-L. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0190-7 · Cited by 1,980 · see citing works

Effects of dalcetrapib in patients with a recent acute coronary syndrome

Schwartz, G. G., Olsson, A. G., Abt, M., Ballantyne, C. M., Barter, P. J., Brumm, J., Chaitman, B. R., Holme, I. M., Kallend, D., Leiter, L. A., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1206797 · Cited by 2,022 · see citing works

Cholesterol, inflammation and innate immunity.

Tall, A. R., & Yvan-Charvet, L. (2015) · Nature Reviews Immunology · doi:10.1038/nri3793 · Cited by 1,479 · see citing works

HDL cholesterol efflux capacity and incident cardiovascular events

Rohatgi, A., Khera, A., Berry, J. D., Givens, E. G., Ayers, C. R., Wedin, K. E., Neeland, I. J., Yuhanna, I. S., Rader, D. R., de Lemos, J. A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1409065 · Cited by 1,390 · see citing works

Dietary fats and cardiovascular disease: a presidential advisory from the American Heart Association

Sacks, F. M., Lichtenstein, A. H., Wu, J. H. Y., Appel, L. J., Creager, M. A., Kris-Etherton, P. M., Miller, M., Rimm, E. B., Rudel, L. L., Robinson, J. G., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000510 · Cited by 1,386 · see citing works

Scavenger receptors in homeostasis and immunity

Canton, J., Neculai, D., & Grinstein, S. (2013) · Nature Reviews Immunology · doi:10.1038/nri3515 · Cited by 838 · see citing works

Dysfunctional HDL and atherosclerotic cardiovascular disease

Rosenson, R. S., Brewer, H. B., Ansell, B. J., Barter, P., Chapman, M. J., Heinecke, J. W., Kontush, A., Tall, A. R., & Webb, N. R. (2016) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.124 · Cited by 822 · see citing works

Mendelian randomization in cardiometabolic disease: challenges in evaluating causality

Holmes, M. V., Ala-Korpela, M., & Smith, G. D. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.78 · Cited by 679 · see citing works

HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells

Tabet, F., Vickers, K. C., Cuesta Torres, L. F., Wiese, C. B., Shoucri, B. M., Lambert, G., Catherinet, C., Prado-Lourenco, L., Levin, M. G., Thacker, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms4292 · Cited by 428 · see citing works

Angiogenesis in the atherosclerotic plaque

Camaré, C., Pucelle, M., Nègre-Salvayre, A., & Salvayre, R. (2017) · Redox Biology · doi:10.1016/j.redox.2017.01.007 · Cited by 401 · see citing works

HDL-targeted therapies: progress, failures and future

Kingwell, B. A., Chapman, M. J., Kontush, A., & Miller, N. E. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4279 · Cited by 354 · see citing works

High-density lipoproteins: A consensus statement from the National Lipid Association

Toth, P. P., Barter, P. J., Rosenson, R. S., Boden, W. E., Chapman, M. J., Cuchel, M., D'Agostino, R. B., Davidson, M. H., Davidson, W. S., Heinecke, J. W., et al. (2013) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2013.08.001 · Cited by 336 · see citing works

Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks

Li, X.-M., Tang, W. H. W., Mosior, M. K., Huang, Y., Wu, Y., Matter, W., Gao, V., Schmitt, D., DiDonato, J. A., Fisher, E. A., et al. (2013) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.113.301373 · Cited by 301 · see citing works

HDL cholesterol: reappraisal of its clinical relevance

März, W., Kleber, M. E., Scharnagl, H., Speer, T., Zewinger, S., Ritsch, A., Parhofer, K. G., von Eckardstein, A., Landmesser, U., & Laufs, U. (2017) · Clinical Research in Cardiology · doi:10.1007/s00392-017-1106-1 · Cited by 275 · see citing works

ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys

Gusarova, V., Alexa, C. A., Wang, Y., Rafique, A., Kim, J. H., Buckler, D., Mintah, I. J., Shihanian, L. M., Cohen, J. C., Hobbs, H. H., et al. (2015) · Journal of Lipid Research · doi:10.1194/jlr.m054890 · Cited by 210 · see citing works

Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement

Hegele, R. A., Borén, J., Ginsberg, H. N., Arca, M., Averna, M., Binder, C. J., Calabresi, L., Chapman, M. J., Cuchel, M., von Eckardstein, A., et al. (2020) · The Lancet Diabetes &amp; Endocrinology · doi:10.1016/s2213-8587(19)30264-5 · Cited by 204 · see citing works

Macrophage mitochondrial energy status regulates cholesterol efflux and is enhanced by anti-miR33 in atherosclerosis

Karunakaran, D., Thrush, A. B., Nguyen, M.-A., Richards, L., Geoffrion, M., Singaravelu, R., Ramphos, E., Shangari, P., Ouimet, M., Pezacki, J. P., et al. (2015) · Circulation Research · doi:10.1161/circresaha.117.305624 · Cited by 188 · see citing works

Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice

Xu, Y., Li, F., Zalzala, M., Xu, J., Gonzalez, F. J., Adorini, L., Lee, Y., Yin, L., & Zhang, Y. (2016) · Hepatology · doi:10.1002/hep.28712 · Cited by 172 · see citing works

Microdomains, Inflammation, and Atherosclerosis

Sorci-Thomas, M. G., & Thomas, M. J. (2016) · Circulation Research · doi:10.1161/circresaha.115.306246 · Cited by 165 · see citing works

National lipid association annual summary of clinical lipidology 2016

Bays, H. E., Jones, P. H., Orringer, C. E., Brown, W. V., & Jacobson, T. A. (2016) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2015.08.002 · Cited by 128 · see citing works

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

Aho, V., Ollila, H. M., Kronholm, E., Bondia-Pons, I., Soininen, P., Kangas, A. J., Hilvo, M., Seppälä, I., Kettunen, J., Oikonen, M., et al. (2016) · Scientific Reports · doi:10.1038/srep24828 · Cited by 126 · see citing works

Genetic dissection of the impact of miR-33a and miR-33b during the progression of atherosclerosis

Price, N. L., Rotllan, N., Canfrán-Duque, A., Zhang, X., Pati, P., Arias, N., Moen, J., Mayr, M., Ford, D. A., Baldán, Á., et al. (2017) · Cell reports · doi:10.1016/j.celrep.2017.10.023 · Cited by 129 · see citing works

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance

Price, N. L., Singh, A. K., Rotllan, N., Goedeke, L., Wing, A., Canfrán-Duque, A., Diaz-Ruiz, A., Araldi, E., Baldán, Á., Camporez, J.-P., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.01.074 · Cited by 110 · see citing works

Dietary Patterns and Cardiovascular Disease Risk in People with Type 2 Diabetes

Archundia Herrera, M. C., Subhan, F. B., & Chan, C. B. (2017) · Current Obesity Reports · doi:10.1007/s13679-017-0284-5 · Cited by 98 · see citing works

Apolipoprotein A-I Infusion Therapies for Coronary Disease: Two Outs in the Ninth Inning and Swinging for the Fences

Rader, D. J. (2018) · JAMA Cardiology · doi:10.1001/jamacardio.2018.2168 · Cited by 32 · see citing works

RNA-binding proteins in vascular inflammation and atherosclerosis

Sachse, M., Tual-Chalot, S., Ciliberti, G., Amponsah-Offeh, M., Stamatelopoulos, K., Gatsiou, A., & Stellos, K. (2023) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2023.01.008 · Cited by 29 · see citing works

DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION

Mustafa, N. H., Kelesbayev, D., & Alibekova, Z. D. (2018) · The Journal of Economic Research & Business Administration · doi:10.26577/be-2018-2-2141

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

Genentech taps Affimed’s antibodies

Cross, R. (2018) · C&EN Global Enterprise · doi:10.1021/cen-09635-buscon15

KOMPLIKASI REGIONAL ANESTESI PADA PEDIATRIK

Sari, D. (2023) · Jurnal Komplikasi Anestesi · doi:10.22146/jka.v5i1.7322

Enxerto livre de arteria epigastrica inferior: avaliacao hemodinamica e angiografica pre e pos-operatoria

Dib, A., Puig, L. B., Salvadori, D., et al. (1988) · Arquivos Brasileiros de Cardiologia