Vaulont, Sophie

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 ( USF2 ) knockout mice

Nicolas, G., Bennoun, M., Devaux, I., Beaumont, C., Grandchamp, B., Kahn, A., & Vaulont, S. (2001) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 1,233

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

Nicolas, G., Chauvet, C., Viatte, L., Danan, J. L., Bigard, X., Devaux, I., Beaumont, C., Kahn, A., & Vaulont, S. (2002) · Journal of Clinical Investigation

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 1,214

Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

Nicolas, G., Bennoun, M., Porteu, A., Mativet, S., Beaumont, C., Grandchamp, B., Sirito, M., Sawadogo, M., Kahn, A., & Vaulont, S. (2002) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersTrace Elements in Health

Cited by 880

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)

Peyssonnaux, C., Zinkernagel, A. S., Schuepbach, R. A., Rankin, E., Vaulont, S., Haase, V. H., Nizet, V., & Johnson, R. S. (2007) · Journal of Clinical Investigation

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 639

Knockout of the α2 but Not α1 5′-AMP-activated Protein Kinase Isoform Abolishes 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranosidebut Not Contraction-induced Glucose Uptake in Skeletal Muscle

Jørgensen, S. B., Viollet, B., Andreelli, F., Frøsig, C., Birk, J. B., Schjerling, P., Vaulont, S., Richter, E. A., & Wojtaszewski, J. F. P. (2004) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 553

HIF-2α, but not HIF-1α, promotes iron absorption in mice

Mastrogiannaki, M., Matak, P., Keith, B., Simon, M. C., Vaulont, S., & Peyssonnaux, C. (2009) · Journal of Clinical Investigation

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 502

The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity

Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Geloen, A., Flamez, D., Mu, J., Lenzner, C., Baud, O., Bennoun, M., et al. (2003) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 499

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

Kautz, L., Meynard, D., Monnier, A., Darnaud, V., Bouvet, R., Wang, R.-H., Deng, C., Vaulont, S., Mosser, J., Coppin, H., et al. (2008) · Blood

Iron Metabolism and DisordersTGF-β signaling in diseases

Cited by 437

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

Nicolas, G., Viatte, L., Lou, D.-Q., Bennoun, M., Beaumont, C., Kahn, A., Andrews, N. C., & Vaulont, S. (2003) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 311

Effects of α‐AMPK knockout on exercise‐induced gene activation in mouse skeletal muscle

Jørgensen, S. B., Wojtaszewski, J. F. P., Viollet, B., Andreelli, F., Birk, J. B., Hellsten, Y., Schjerling, P., Vaulont, S., Neufer, P. D., Richter, E. A., et al. (2005) · The FASEB Journal

Metabolism, Diabetes, and CancerCardiovascular and exercise physiology

Cited by 274

Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis

Lesbordes-Brion, J.-C., Viatte, L., Bennoun, M., Lou, D.-Q., Ramey, G., Houbron, C., Hamard, G., Kahn, A., & Vaulont, S. (2006) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 257

Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models

Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Flamez, D., Mu, J., Wojtaszewski, J. F. P., Schuit, F. C., Birnbaum, M., Richter, E., et al. (2003) · Biochemical Society Transactions

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 241

The α2–5′AMP-Activated Protein Kinase Is a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and Is Responsive to Glucose Loading

Jørgensen, S. B., Nielsen, J. N., Birk, J. B., Olsen, G. S., Viollet, B., Andreelli, F., Schjerling, P., Vaulont, S., Hardie, D. G., Hansen, B. F., et al. (2004) · Diabetes

Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus

Cited by 241

The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

Tong, W.-H., Sourbier, C., Kovtunovych, G., Jeong, S. Y., Vira, M., Ghosh, M., Romero, V. V., Sougrat, R., Vaulont, S., Viollet, B., et al. (2011) · Cancer Cell

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 212

Transcriptional and post-transcriptional regulation of L-type pyruvate kinase gene expression in rat liver.

Vaulont, S., Munnich, A., Decaux, J. F., & Kahn, A. (1986) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus

Cited by 147

Dendritic cell–derived hepcidin sequesters iron from the microbiota to promote mucosal healing

Bessman, N. J., Mathieu, J. R. R., Renassia, C., Zhou, L., Fung, T. C., Fernandez, K. C., Austin, C., Moeller, J. B., Zumerle, S., Louis, S., et al. (2020) · Science

Iron Metabolism and DisordersInflammatory Bowel Disease

Cited by 145

Functional differences between hepcidin 1 and 2 in transgenic mice

Lou, D.-Q., Nicolas, G., Lesbordes, J.-C., Viatte, L., Grimber, G., Szajnert, M.-F., Kahn, A., & Vaulont, S. (2004) · Blood

Iron Metabolism and DisordersHemoglobin structure and function

Cited by 123

The Microbiota Shifts the Iron Sensing of Intestinal Cells

Deschemin, J., Noordine, M., Remot, A., Willemetz, A., Afif, C., Canonne‐Hergaux, F., Langella, P., Karim, Z., Vaulont, S., Thomas, M., et al. (2016) · The FASEB Journal

Gut microbiota and healthIron Metabolism and Disorders

Cited by 108

Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia

Michels, K. R., Zhang, Z., Bettina, A. M., Cagnina, R. E., Stefanova, D., Burdick, M. D., Vaulont, S., Nemeth, E., Ganz, T., & Mehrad, B. (2017) · JCI Insight

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 93

Role of Hepcidin in the Setting of Hypoferremia during Acute Inflammation

Deschemin, J.-C., & Vaulont, S. (2013) · PLoS ONE

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 89

Targeted disruption of hepcidin in the liver recapitulates the hemochromatotic phenotype

Zumerle, S., Mathieu, J. R. R., Delga, S., Heinis, M., Viatte, L., Vaulont, S., & Peyssonnaux, C. (2014) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 87

Iron regulator hepcidin impairs macrophage-dependent cardiac repair after injury

Zlatanova, I., Pinto, C., Bonnin, P., Mathieu, J. R. R., Bakker, W., Vilar, J., Lemitre, M., Voehringer, D., Vaulont, S., Peyssonnaux, C., et al. (2019) · Circulation

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 81

Iron‐ and inflammation‐induced hepcidin gene expression in mice is not mediated by Kupffer cells in vivo†

Lou, D., Lesbordes, J., Nicolas, G., Viatte, L., Bennoun, M., Van Rooijen, N., Kahn, A., Renia, L., & Vaulont, S. (2005) · Hepatology

Iron Metabolism and DisordersTrace Elements in Health

Cited by 62

Deletion of HIF-2α in the enterocytes decreases the severity of tissue iron loading in hepcidin knockout mice

Mastrogiannaki, M., Matak, P., Delga, S., Deschemin, J.-C., Vaulont, S., & Peyssonnaux, C. (2012) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 57