Mullenders, Leon H. F.

Transcription-coupled nucleotide excision repair in mammalian cells: Molecular mechanisms and biological effects

Fousteri, M., & Mullenders, L. H. (2008) · Cell Research

DNA Repair MechanismsNuclear Structure and Function

Cited by 487

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

Ogi, T., Limsirichaikul, S., Overmeer, R. M., Volker, M., Takenaka, K., Cloney, R., Nakazawa, Y., Niimi, A., Miki, Y., Jaspers, N. G., et al. (2010) · Molecular Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 392

RETRACTED: Cockayne Syndrome A and B Proteins Differentially Regulate Recruitment of Chromatin Remodeling and Repair Factors to Stalled RNA Polymerase II In Vivo

Fousteri, M., Vermeulen, W., van Zeeland, A. A., & Mullenders, L. H. F. (2006) · Molecular Cell

DNA Repair MechanismsChromatin Remodeling and Cancer

Cited by 387

Heterochromatin protein 1 is recruited to various types of DNA damage

Luijsterburg, M. S., Dinant, C., Lans, H., Stap, J., Wiernasz, E., Lagerwerf, S., Warmerdam, D. O., Lindh, M., Brink, M. C., Dobrucki, J. W., et al. (2009) · Journal of Cell Biology

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 264

RETRACTED: Sealing of Chromosomal DNA Nicks during Nucleotide Excision Repair Requires XRCC1 and DNA Ligase IIIα in a Cell-Cycle-Specific Manner

Moser, J., Kool, H., Giakzidis, I., Caldecott, K., Mullenders, L. H. F., & Fousteri, M. I. (2007) · Molecular Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 261

The core spliceosome as target and effector of non-canonical ATM signalling

Tresini, M., Warmerdam, D. O., Kolovos, P., Snijder, L., Vrouwe, M. G., Demmers, J. A. A., van IJcken, W. F. J., Grosveld, F. G., Medema, R. H., Hoeijmakers, J. H. J., et al. (2015) · Nature

RNA Research and SplicingDNA Repair Mechanisms

Cited by 252

The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions

Moser, J., Volker, M., Kool, H., Alekseev, S., Vrieling, H., Yasui, A., van Zeeland, A. A., & Mullenders, L. H. F. (2005) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

Cited by 182

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

Garinis, G. A., Uittenboogaard, L. M., Stachelscheid, H., Fousteri, M., van Ijcken, W., Breit, T. M., van Steeg, H., Mullenders, L. H. F., van der Horst, G. T. J., Brüning, J. C., et al. (2009) · Nature Cell Biology

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 138

Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC

Luijsterburg, M. S., Goedhart, J., Moser, J., Kool, H., Geverts, B., Houtsmuller, A. B., Mullenders, L. H. F., Vermeulen, W., & van Driel, R. (2007) · Journal of Cell Science

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 105

UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways

Vrouwe, M. G., Pines, A., Overmeer, R. M., Hanada, K., & Mullenders, L. H. F. (2011) · Journal of Cell Science

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 100

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells

Jansen, J. G., Tsaalbi-Shtylik, A., Hendriks, G., Gali, H., Hendel, A., Johansson, F., Erixon, K., Livneh, Z., Mullenders, L. H. F., Haracska, L., et al. (2009) · Molecular and Cellular Biology

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 99

Differential role of transcription-coupled repair in UVB-induced G 2 arrest and apoptosis in mouse epidermis

van Oosten, M., Rebel, H., Friedberg, E. C., van Steeg, H., van der Horst, G. T. J., van Kranen, H. J., Westerman, A., van Zeeland, A. A., Mullenders, L. H. F., & de Gruijl, F. R. (2000) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsSkin Protection and Aging

Cited by 82

Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation

Alekseev, S., Kool, H., Rebel, H., Fousteri, M., Moser, J., Backendorf, C., de Gruijl, F. R., Vrieling, H., & Mullenders, L. H. F. (2005) · Cancer Research

DNA Repair MechanismsSkin Protection and Aging

Cited by 77

Differential repair of the two major UV-induced photolesions in trichothiodystrophy fibroblasts

Riou, L., Eveno, E., van Hoffen, A., van Zeeland, A. A., Sarasin, A., & Mullenders, L. H. F. (2004) · Cancer Research

DNA Repair MechanismsNuclear Structure and Function

Cited by 46

Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency

Nijhof, J. G. W., van Pelt, C., Mulder, A. A., Mitchell, D. L., Mullenders, L. H. F., & de Gruijl, F. R. (2006) · Carcinogenesis

DNA Repair MechanismsSkin Protection and Aging

Cited by 44

Transcription-Dependent Cytosine Deamination Is a Novel Mechanism in Ultraviolet Light-Induced Mutagenesis

Hendriks, G., Calléja, F., Besaratinia, A., Vrieling, H., Pfeifer, G. P., Mullenders, L. H. F., Jansen, J. G., & de Wind, N. (2010) · Current Biology

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 39

Cellular Concentrations of DDB2 Regulate Dynamic Binding of DDB1 at UV-Induced DNA Damage

Alekseev, S., Luijsterburg, M. S., Pines, A., Geverts, B., Mari, P.-O., Giglia-Mari, G., Lans, H., Houtsmuller, A. B., Mullenders, L. H. F., Hoeijmakers, J. H. J., et al. (2008) · Molecular and Cellular Biology

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 38

Induction of Nevi and Skin Tumors in Ink4a/Arf Xpa Knockout Mice by Neonatal, Intermittent, or Chronic UVB Exposures

van Schanke, A., van Venrooij, G. M. C. A. L., Jongsma, M. J., Banus, H. A., Mullenders, L. H. F., van Kranen, H. J., & de Gruijl, F. R. (2006) · Cancer Research

Skin Protection and Agingmelanin and skin pigmentation

Cited by 38

Persistently stalled replication forks inhibit nucleotide excision repair in trans by sequestering Replication protein A

Tsaalbi-Shtylik, A., Moser, J., Mullenders, L. H. F., Jansen, J. G., & de Wind, N. (2014) · Nucleic Acids Research

DNA Repair MechanismsNuclear Structure and Function

Cited by 28